The DOI matches its Crossref record; 30 of the 31 references it cites were found in a registry or an index.
Mediterranean-style dietary pattern, reduced risk of metabolic syndrome traits, and incidence in the Framingham Offspring Cohort
Open accessAbstract
Background The benefit of the Mediterranean-style dietary pattern in mitigating metabolic risk factors for type 2 diabetes and cardiovascular disease has not been well investigated among nondiabetic Americans.Objective The aim of this study was to examine the prospective association between the Mediterranean-style dietary pattern and metabolic syndrome.Design The Mediterranean-style dietary pattern score (MSDPS) was used to characterize a Mediterranean-style dietary pattern in the Framingham Heart Study Offspring Cohort. We examined the longitudinal association between MSDPS and metabolic syndrome traits (including homeostasis model assessment-insulin resistance, fasting glucose, waist circumference, triglyceride, HDL cholesterol, and systolic and diastolic blood pressure) among 2730 participants of the Framingham Heart Study Offspring Cohort without type 2 diabetes (baseline median age: 54 y; 55% women), who were followed from the fifth (baseline) to the seventh study examinations (mean follow-up time: 7 y), and metabolic syndrome incidence (according to the National Cholesterol Education Program Adult Treatment Panel III definition) in 1918 participants free of the condition at baseline.Results A higher MSDPS was associated with lower homeostasis model assessment-insulin resistance (P = 0.02), waist circumference (P < 0.001), fasting plasma glucose (P = 0.03), and triglycerides (P < 0.001) and higher HDL cholesterol (P = 0.02) after adjustment for the corresponding baseline values and for several confounding factors associated with type 2 diabetes risk. Participants in the highest quintile category of the MSDPS had a lower incidence of metabolic syndrome than those in the lowest quintile category (38.5% compared with 30.1%; P = 0.01).Conclusion Our study suggests that the consumption of a diet consistent with the principles of the Mediterranean-style diet may protect against metabolic syndrome in Americans.
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“10%-15% reduction in plasma TG levels with Mediterranean diet”
From The Forgotten Lipids: Triglycerides, Remnant Cholesterol, and Atherosclerotic Cardiovascular Disease Risk (2019) · cites this paper as [135]
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“Epidemiological and clinical trial evidence suggests that the Mediterranean-style dietary pattern 398,399 is associated with decreased triglyceride levels.”
From Triglycerides and Cardiovascular Disease: A Scientific Statement From the American Heart Association (2011) · cites this paper as [399]
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Cites
Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502
Toprak, Ö., Kurt, H., Sarı, Y., Şarkış, C., Us, H., & Kırık, A. (2017) · Kidney & Blood Pressure Research · doi:10.1159/000468530 · Cited by 29,772
Grundy, S. M., Cleeman, J. I., Daniels, S. R., Donato, K. A., Eckel, R. H., Franklin, B. A., Gordon, D. J., Krauss, R. M., Savage, P. J., Smith, S. C., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.169404 · Cited by 11,961
Ford, E. S., Giles, W. H., & Dietz, W. H. (2002) · JAMA · doi:10.1001/jama.287.3.356 · Cited by 6,698
Willett, W. C. (1998) · doi:10.1093/acprof:oso/9780195122978.001.0001 · Cited by 4,541
Rosamond, W., Flegal, K., Friday, G., Furie, K., Go, A., Greenlund, K., Haase, N., Ho, M., Howard, V., Kissela, B., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.179918 · Cited by 3,277
Self-citationPredicting basal metabolic rate, new standards and review of previous work.
Wn, S. (1985) · PubMed · Cited by 2,955
Esposito, K., Marfella, R., Ciotola, M., Di Palo, C., Giugliano, F., Giugliano, G., D'Armiento, M., D'Andrea, F., & Giugliano, D. (2004) · JAMA · doi:10.1001/jama.292.12.1440 · Cited by 2,126
Rimm, E. B., Giovannucci, E. L., Stampfer, M. J., Colditz, G. A., Litin, L. B., & Willett, W. C. (1992) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a116211 · Cited by 2,104
Metabolic Syndrome as a Precursor of Cardiovascular Disease and Type 2 Diabetes Mellitus
Wilson, P. W. F., D’Agostino, R. B., Parise, H., SULLIVAN, L. M., & Meigs, J. B. (2005) · Circulation · doi:10.1161/circulationaha.105.539528 · Cited by 2,050
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1 of the 31 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- 1999, Dietary guidelines for adults in Greece., Arch Hellenic Med, 16, 516
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Items 201–246 of 246
Elfassy, T., Juul, F., Mesa, R., Palaniappan, L., Srinivasan, M., & Yi, S. S. (2023) · Research on Aging · doi:10.1177/01640275231222928 · Cited by 1
“…with key cardiometabolic risk factors (obesity, hypertension, high cholesterol, and diabetes) that can result from poor diet (Rakhra et al., 2020; Rumawas et al., 2009; Sacks et al., 2001) and are associated with cardiovascular health (Lloyd-Jones et al., 2022), within older and racial/ ethnic…”
BackgroundYubero‐Serrano, E. M., Gutierrez-Mariscal, F. M., Ojeda‐Rodríguez, A., Pérez‐Martínez, P., & López‐Miranda, J. (2025) · Nutrition and health · doi:10.1007/978-3-031-87441-3_2 · Cited by 1
Diet Quality Assessed with the “Framingham Nutritional Risk Score”
Kimokoti, R. W., & Millen, B. E. (2013) · Springer eBooks · doi:10.1007/978-1-4614-7315-2_22 · Cited by 1
“Whereas the FNRS was associated with abdominal obesity only of the MetS components, mean levels of waist circumference, glucose, and triglycerides were highest and mean HDL-cholesterol level was lowest among adults with a lower MSDPS score [38].”
BackgroundOverweight, Obesity, and Cardiovascular Risk
Blackburn, G. L., Spellman, K., & Wollner, S. B. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-1366-4.00019-6 · Cited by 1
Higher Ca and Na content in the hair of obese people in Poland
Kwiecień, M., Samolińska, W., Puczkowski, S., Waśko, M., & Blicharski, T. (2019) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831/a000557 · Cited by 1
Yubero‐Serrano, E. M., Gutierrez-Mariscal, F. M., Pérez‐Martínez, P., & López‐Miranda, J. (2020) · Springer eBooks · doi:10.1007/978-3-030-30892-6_2 · Cited by 1
Setayeshgar, Z. (2014) · University Library - University of Saskatchewan (University of Saskatchewan) · Cited by 1
Dietary patterns: designs for progress and approaches for health impact
Schwenke, D. C. (2010) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e328339b58c · Cited by 1
A Cross-national Comparison Study of Metabolic Syndrome among Canadian and Korean Older Adults
Song, G. J. (2014) · UWSpace (University of Waterloo) · Cited by 1
Fernández‐Montero, A., & Martínez-González (2013) · Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)
Food and nutrition issues for the future
Tapsell, L. C. (2010) · Nutrition & Dietetics · doi:10.1111/j.1747-0080.2010.01408.x
Therapy and clinical trials: new insights
Pellegatta, F., Grigore, L., & Catapano, A. L. (2010) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e32833c2260
13 trucos para sobrevivir al turno de 12 horas
Kolasa, K. M., & Firnhaber, G. C. (2012) · Nursing (Ed española) · doi:10.1016/s0212-5382(12)70056-0
Pohjoismaisen ruokavalion yhteys lihavuuteen ja sen metabolisiin riskitekijöihin
Kanerva, N. (2014) · STM:n Hallinnonalan avoin julkaisuarkisto (Julkari)
Hellstrand, S. (2015) · Lund University Publications (Lund University)
Park, Y. I., & Joo, N. (2014) · Nutrition Research and Practice · doi:10.4162/nrp.2014.8.4.432
“Several lifestyle factors including a smoking, alcohol consumptions, exercising, and eating habits have been found to influence metabolic syndrome abnormalities [3-7].”
BackgroundMetabolic syndrome: a disease of the brain
Singh, R., Fabien, D. M., & Wilczynska, A. (2010) · Journal of Clinical & Experimental Dermatology Research
Berry, E. M., & Donini, L. M. (2012)
Atherosclerotic Cardiovascular Disease in a Patient With Metabolic Syndrome
Zelig, R. S., Cohen, M. C., Davidson, P., & Ziegler, J. (2014) · Topics in Clinical Nutrition · doi:10.1097/01.tin.0000445901.82770.4d
Impact of Mediterranean Diet on Metabolic Syndrome
Khayef, G., & Sabaté, J. (2016) · Springer eBooks · doi:10.1007/978-3-319-27969-5_9
Triglycerides and Cardiovascular Disease: A Scientific Statement From the American
Lennie, T. A., Levi, M., Mazzone, T., Pennathur, S., Goldberg, A. C., Howard, W. J., Jacobson, M. Z., Stone, N. J., Ballantyne, C. M., Bittner, V., et al. (2013)
The ‘Mediterranean diet’ and weight management
Bes‐Rastrollo, M., & Martínez‐González, M. Á. (2014) · Elsevier eBooks · doi:10.1533/9781782420996.2.109
The Mediterranean Diet Versus a Low-Fat Diet, Cardiovascular Risk Factors, and Obesity
Fernández, M. L. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-407849-9.00033-6
Diet, lifestyle and type 2 diabetes in China
He, Y. (2014) · doi:10.18174/304900
“Low birth weight has also been found to predict diabetes and the metabolic syndrome in Asian adults and children (37, 38, 40), thus lending support to the notion that fetal programming with exposure to poor nutrition in utero or during early childhood can promote a fat preserving or thrifty phenotype.”
BackgroundTreatment of Lipid Metabolism Disturbances in Autoimmune Diseases
Ronda, N., & Meroni, P. L. (2017) · Technical report · doi:10.1016/b978-0-12-803997-7.00007-7
Nada, A. M. (2014) · Zagazig University Medical Journal · doi:10.21608/zumj.2014.4368
Mediterranean Diet as a Potential Strategy to Reduce Cognitive Decline and Dementia in Elderly
Knight, A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811959-4.00012-2
Cardiovascular and Retinal Vascular Changes in Preclinical Alzheimer's Disease
Santos, C. (2018) · Digital Commons - URI (University of Rhode Island) · doi:10.23860/diss-santos-claudia-2018
Association between Maternal Dietary Patterns during Pregnancy and Early Childhood Growth Outcomes
Martin, C. L. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/z74k-6794
Healthy Diet for Older Adults: A Focus on Mediterranean Diet
Newberry, C. A., & Pickett‐Blakely, O. (2020) · Springer eBooks · doi:10.1007/978-3-319-90761-1_28-1
13 tips for surviving the 12-hour shift
Kolasa, K. M., & Firnhaber, G. C. (2012) · Nursing Critical Care · doi:10.1097/01.ccn.0000414160.20939.93
Is the Second Law of Thermodynamics Able to Classify Drugs?
Schwartz, L. H., Benichou, L., Schwartz, J., Pontié, M., & Henry, M. (2022) · Substantia · doi:10.36253/substantia-1364
Foster-Nicholas, L. A., Shavlik, D. J., Heskey, C. E., Dyett, P. A., & Segovia‐Siapco, G. (2022) · Research Square · doi:10.21203/rs.3.rs-1526807/v1
Hoffman, R. M., & Gerber, M. (2011) · Wiley eBooks · doi:10.1002/9781118785027.ch10
Mediterranean Diet and Metabolic Syndrome
Gouveri, E., Drakopanagiotakis, F., & Diamantopoulos, E. J. (2015) · CRC Press eBooks · doi:10.1201/b19099-32
Healthy Diet for Older Adults: A Focus on Mediterranean Diet
Newberry, C. A., & Pickett‐Blakely, O. (2021) · Springer eBooks · doi:10.1007/978-3-030-30192-7_28
The Mediterranean diet and metabolic syndrome
Gouveri, E., Marakomichelakis, G., & Diamantopoulos, E. J. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818649-7.00034-5
Echeverría, G., Berkowitz, L., Love, G. D., Ryff, C. D., & Rigotti, A. (2022) · doi:10.2196/preprints.44245
An Overview of Dietary Approaches to Prevent the Development of Glaucoma
Kapur, P., Ashok, P., Gupta, S., Bhardwaj, M., & Suri, M. (2020) · The Indian Journal of Nutrition and Dietetics · doi:10.21048/ijnd.2020.57.3.23638
Merz, S., Jaehn, P., & Holmberg, C. (2023) · Science as Culture · doi:10.1080/09505431.2023.2255200
“The longest running cohort study, the Framingham Heart Study, started in the late 1940s in the US and is still running today; most publicly available knowledge about ‘ healthy diets ’ or the importance of a ‘ Mediterranean diet ’ are derived from it (Rumawas et al. , 2009).”
BackgroundLongitudinal associations between dietary diversity and serum lipid markers in Japanese workers
Bui, T. T., Nakamoto, M., Yamada, K., Nakamoto, A., HATA, A., Aki, N., Shikama, Y., Bando, Y., Ichihara, T., Minagawa, T., et al. (2024) · European Journal of Clinical Nutrition · doi:10.1038/s41430-024-01540-7
“A cohort study on the bene fi ts of a high Mediterranean-style dietary pattern score showed that a higher score was associated with a lower level of triglycerides and a high level of HDL cholesterol [18].”
Assessment Of Adherence To The Mediterranean Diet In Adults With Metabolic Syndrome
Erdekli, H. A., & Köse, S. (2026) · Journal of Advanced Studies in Health Science and Obesity · doi:10.51271/jashso.55
“Among those following the this dietary pattern, improvements were observed in several MetS components, including abdominal obesity, insulin resistance, and dyslipidemia (10).”
InfluentialAlimentation et asthme dans la cohorte NutriNet-Santé
Andrianasolo, R. M. (2019) · theses.fr (ABES) · doi:10.70675/6ddfd2b5z78e2z4c83zbfa7zc5c30f3d51ee
Pan, Y., Zhang, N., Tong, X., Chen, G., Li, X., Wu, J., Fang, J., Li, D., Wu, L., Peng, S., et al. (2026) · BMJ Public Health · doi:10.1136/bmjph-2026-005263
Nutritional Management of Hypertension: Cost Versus Benefit
Mavrodaris, A., & Stranges, S. (2010) · Humana Press eBooks · doi:10.1007/978-1-60761-308-4_21
“A study conducted among 2,730 participants of the Framingham Heart Study Offspring Cohort without type 2 diabetes analyzed the longitudinal association between Mediterranean dietary pattern and metabolic syndrome traits over a mean follow-up time of 7 years [38].”
Method
Metadata
- Authors
- Rumawas, M. E., Meigs, J. B., Dwyer, J. T., McKeown, N. M., & Jacques, P. F.
- Affiliations
- Tufts University (US)
- Corresponding author
- Jacques, Paul F
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 2009-12
- Volume
- 90
- Issue
- 6
- Pages
- 1608-1614
- ISSN
- 0002-9165 (ISSN-L)
- PMC
- PMC3152203
- OpenAlex
- W2135320605
- Cited by
- 246
- References
- 31
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 10 · 2023: 8 · 2022: 10 · 2021: 15 · 2020: 13 · 2019: 12 · 2018: 11 · 2017: 10 · 2016: 20 · 2015: 22 · 2014: 27 · 2013: 18 · 2012: 26
- FWCI
- 21.75
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- American Journal of Clinical Nutrition (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- USDA (58-1950-7-707)
- NIH (NO1-HC-25195)
- National Institute of Diabetes and Digestive and Kidney Diseases (K24 DK080140)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Nutrition, Genetics, and Disease
- Keywords
- Mediterranean diet, metabolic syndrome, metabolic syndrome incidence, insulin resistance, waist circumference, fasting blood glucose, triglycerides, HDL cholesterol, blood pressure, Framingham Offspring cohort, type 2 diabetes risk
- MeSH terms
- Female, Humans, Insulin Resistance, Male, Middle Aged, Prospective Studies, Risk, Cohort Studies, Incidence, Metabolic Syndrome, Diet, Mediterranean
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