Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response

Panda, Alexander, Qian, Feng, Mohanty, Subhasis, van Duin, David, Newman, Frances K, Zhang, Lin, Chen, Shu, Towle, Virginia +5 more·2010·The Journal of Immunology

DOI 10.4049/jimmunol.0901022

Cited by (552)

Items 301–400 of 552

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Diane Longo, Brent Louie, Jason Ptacek, Greg Friedland, Erik Evensen, Santosh Putta, Michelle B. Atallah, David C. Spellmeyer, Ena Wang, Zoltán Pós et al. · 2014 · Journal of Translational Medicine