Age-Associated Decrease in TLR Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response

Panda, Alexander, Qian, Feng, Mohanty, Subhasis, van Duin, David, Newman, Frances K, Zhang, Lin, Chen, Shu, Towle, Virginia, Belshe, Robert B, Fikrig, Erol, Allore, Heather G, Montgomery, Ruth R, Shaw, Albert C·2010·The Journal of Immunology
DOI 10.4049/jimmunol.0901022

Cited by (552)

Items 501–552 of 552

  1. Identification and characterization of senescence-associated microRNAs in a mouse model of the XFE progeroid syndrome
    Lolita S. Nidadavolu · 2013 · D-Scholarship@Pitt (University of Pittsburgh)
  2. Asthma and Aging
    Nicola Alexander Hanania, Paula Jane Busse · 2015 · Springer eBooks
  3. Autologous human kidney proximal tubule epithelial cells (PTEC) modulate dendritic cell (DC), T cell and B cell responses
    Sandeep Sampangi · 2015 · QUT ePrints (Queensland University of Technology)
  4. The Aging Immune System, Vaccine Efficacy, and the Lung
    Jenna M. Bartley, Laura Haynes · 2015 · WORLD SCIENTIFIC eBooks
  5. LETTERS TO THE EDITOR The Influence of Age on the Clinical Features and Outcomes of Anti-Glomerular Basement Membrane Disease
    Se Jin Park, Ji Hong Kim, Zhao Cui, Minghui Zhao · 2011
  6. Assessment of Toll-Like Receptor Expression and Function by Flow Cytometry
    Subhasis Mohanty, Albert C. Shaw · 2016 · WORLD SCIENTIFIC eBooks
  7. Rationale Antibiotikatherapie bei chronischer Niereninsuffizienz
    Matthias Girndt · 2016 · Der Nephrologe
  8. Influence of Aging on Antigen Uptake and Cytokine Production by Dendritic Cells
    Karen Henriette Pinke, Heliton Gustavo de Lima, Vanessa Soares Lara · 2017 · Springer eBooks
  9. The Triple Immune Argument; Surveillance/Evasion/ Senescence and the Increased Incidence of Acute Myeloid Leukemia Observed with Age
    Manar Mohammad Ismail · 2017 · American Journal of Immunology
  10. Frailty in Old Age is Associated with Altered Cytokine Production in Response to TLR Ligation
    Nathalie Compté, Thierry Pepersack, Stanislas Goriely · 2017 · Springer eBooks
  11. Immune Modulation and Its Role in Antiaging
    Mustafa Erinç Sitar, Elçin Akduman Alaşehir, Belkız Öngen İpek · 2018 · Springer eBooks
  12. Immunomodulation by raw bovine milk and its ingredients: effects in nutritional intervention, oral vaccination and trained immunity
    M. van Splunter · 2018
  13. Altération des réponses vaccinales avec l’âge
    Brigitte Autran · 2019 · Revue des Maladies Respiratoires
  14. Identifying Comorbid Risk Factors of West Nile Neuroinvasive Disease in the Ontario Population, 2002-2012, Using Laboratory and Health Administrative Data
    Jessica Sutinen · 2020 · uO Research (University of Ottawa)
  15. SARS-CoV-2 B cell receptor signatures in at-risk populations
    Andrew I. Flyak · 2020 · Journal of Clinical Investigation
  16. Characteristics of the Immunoresponse in Elderly People and Autoimmunity
    O.V. Moskalets · 2020 · Advances in Gerontology
  17. Modulation of adaptive immunity through acute exercise, metabolism-targeting pharmacological agents, and chronic exercise training
    Jessica Alley · 2021 · Iowa State University Digital Repository (Iowa State University)
  18. Estudio celular de la inmunosenescencia en adultos mayores vacunados y en pacientes con cáncer de mama
    Rodríguez Rodríguez, Ivon Johanna · 2021
  19. Optimizing Response to Vaccination in the Elderly
    Diana Boraschi, Rino Rappuoli, Giuseppe Del Giudice · 2013 · Springer eBooks
  20. Impact of physical activity on immune function and inflammation in the elderly
    David B. Bartlett · 2014 · University of Birmingham Institutional Research Archive (University of Birmingham)
  21. Age-Related Impairment of Innate and Adaptive Immune Responses Following Intranasal Herpes Simplex Infection
    Ruchi Srivastava, Anshu Agrawal, Hawa Vahed, Lbachir BenMohamed · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  22. Nonhuman Primate Models of Immunosenescence
    Andrea Rivera, Maham Rais, Tasha Barr, Nicole D. Arnold, Suhas Sureshchandra, Ilhem Messaoudi · 2017 · Springer eBooks
  23. Aging Immunity and the Impact of Physical Exercise
    Austin B. Bigley, Forrest L. Baker, Guillaume Spielmann, Richard J. Simpson · 2017 · Springer eBooks
  24. Influence of Aging on Antigen Uptake and Cytokine Production by Dendritic Cells
    Karen Henriette Pinke, Heliton Gustavo de Lima, Vanessa Soares Lara · 2019 · Springer eBooks
  25. Immune Senescence
    Kevin P. High · 2014 · Wiley eBooks
  26. Faculty Opinions recommendation of Phylogenetic analysis of the human antibody repertoire reveals quantitative signatures of immune senescence and aging.
    Dario Riccardo Valenzano · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  27. Role of Dendritic Cells in Aging
    Anshu Agrawal, Sudhanshu Agrawal, Sudhir Gupta · 2019 · Springer eBooks
  28. Relation between the number of the older adults patients hospitalized for pneumonia and air particulate matter exposure: a time-stratified case-crossover study in multiple cities
    Chengwei Lin, Wanyanhan Jiang, Gao Xi, Yi He, Jia Li, Chengchao Zhou, Lian Yang · 2022 · Research Square
  29. Innate immune responses in COVID-19
    Etienne D. Jacotot, Laura Talamini, Srinivasa Reddy Bonam, Angelica Thomas Vieira, Véronique Frémeaux‐Bacchi, Marko Z. Radic, Marie‐Agnès Dragon‐Durey, José Manuel Lozano, Rafael Simone Saia, Sylviane Muller · 2023 · Elsevier eBooks
  30. Age-Related Impairment of Innate and Adaptive Immune Responses Exacerbate Respiratory Viral Infection in Older Mice
    Ruchi Srivast, Anshu Agrawal, Hawa Vahed, Lbachir BenMohamed · 2023 · Research Square
  31. Tailoring Vaccines for Older Individuals: Aging of the Immune System and the Impact on Vaccine Efficacy
    Shazia Bashir, Maria Wilson, Diane A.I. Ashiru-Oredope, Sudaxshina Murdan · 2023 · AAPS advances in the pharmaceutical sciences series
  32. Type I Interferon and COVID-19
    Bahman Rahimlou, Mohammad Reza Ghazanfari, Niki Ghambari Mohammadi · 2023 · Immunoregulation
  33. Efeito da suplementação dietética com ácido graxo ômega-3 na resposta imunológica, hepática e muscular de camundongos knockout IL-10
    Daniela Dalpubel Campanari · 2024 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  34. Immunological Properties of Adjuvants
    Malcolm S. Duthie, Steven G. Reed · 2025 · Elsevier eBooks
  35. Additional file 1 of Novel nanoadjuvants balance immune activation with modest inflammation: implications for older adult vaccines
    Kathleen A. Ross, April M Tingle, Sujata Senapati, Kaitlyn G. Holden, Michael J. Wannemuehler, Surya K. Mallapragada, Balaji Narasimhan, Kohut, Marian L. · 2023 · Figshare
  36. Additional file 3 of Altered transcriptional responses in the lungs of aged mice after influenza infection
    Hernandez, Ana M., Jim A. Mossman, Toapanta, Franklin R., Dana M. Previte, Ross, Ted M., Gerard J. Nau · 2022 · Figshare
  37. Additional file 2 of Altered transcriptional responses in the lungs of aged mice after influenza infection
    Hernandez, Ana M., Jim A. Mossman, Franklin R. Toapanta, Dana M. Previte, Ross, Ted M., Gerard J. Nau · 2022 · Figshare
  38. Additional file 1 of Altered transcriptional responses in the lungs of aged mice after influenza infection
    Hernandez, Ana M., Jim A. Mossman, Franklin R. Toapanta, Previte, Dana M., Ross, Ted M., Gerard J. Nau · 2022 · Figshare
  39. Additional file 1 of “Just right” combinations of adjuvants with nanoscale carriers activate aged dendritic cells without overt inflammation
    Ananya Ananya, Kaitlyn G. Holden, Gu, Zhiling, Nettleton, Dan, Surya K. Mallapragada, Michael J. Wannemuehler, Kohut, Marian L., Balaji Narasimhan · 2023 · Figshare
  40. Additional file 1 of Sex differences in the percentage of IRF5 positive B cells are associated with higher production of TNF-α in women in response to TLR9 in humans
    Claudia Beisel, Ana Jordan-Paiz, Sandra Köllmann, Annika Elise Ahrenstorf, Benedetta Padoan, Tanja Barkhausen, Marylyn M. Addo, Marcus A. Altfeld · 2024 · Figshare
  41. Respiratory virus immune response in the aged host
    Olivia Bartlett Parks, Anusha Kalavacharla, John V. Williams · 2026 · Immunity & Ageing
  42. An inflammation-defying adjuvant “micro”manages age-diminished vaccine efficacy
    Guanqun Liu · 2026 · Molecular Therapy — Nucleic Acids
  43. Age‐related differences in mRNA vaccine immunogenicity and adjuvancy
    Shivali Savita Chinni, Gemma S. Trollope, Patrick Leung, Jonathan Luke McQualter, Chee Wah Tan, LinFa Wang, Leonard Lim, Adam K. Wheatley, Jennifer A. Juno, Stephen John Kent et al. · 2026 · Immunology and Cell Biology
  44. Étude des liens physiopathologiques entre la pseudo polyarthrite rhizomélique et l’artérite à cellules géantes.
    André Ramon · 2025 · theses.fr (ABES)
  45. Longitudinal SARS-CoV-2 seroprevalence among learners, parents, and teachers in a South African school community
    Reshmi Dassaye, Terusha Chetty, Brodie B. Daniels, Trisha Ramraj, Samkelisiwe Buthelezi, Khanya Mohlabi, Tarylee Reddy, Isaac L. Singini, Nomonde Gwebushe, Ameena Ebrahim Goga · 2026 · Frontiers in Public Health
  46. Innate Immune System Biomarkers in Asthma in Older Age: A Mini Review
    Fatemeh Zamani, Rasoul Nasiri Kalmarzi, Khaled Fathizadeh, Naseh Sigari, Sabah Hasani, Ramin Lotfi, Abbas Khosravi · 2026 · Archives of Iranian Medicine
  47. How age and sex interaction is associated with immune aging with implications for vaccines and age-related autoimmunity
    Reza Gheitasi, Mahnaz Rezaei, Parvaneh Nafisi Fard, Daniela Roel, Sabine Baumgart, Diana Dudziak, Norman Rose, Simon Michael Petzinna, Thomas Kamradt, Carsten Watzl et al. · 2026 · npj Aging
  48. Remodeling of innate antiviral immunity in aging
    Xu Zhang, Qing Yang · 2026 · Cell Insight
  49. BindingDB Entry 50045319: Human Toll-like receptor 8-selective agonistic activities in 1-alkyl-1H-benzimidazol-2-amines.
    BindingDB · 2016 · UC San Diego
  50. Proteomic signatures
    Ted Ross · 2025 · ImmPort
  51. Toll-like Receptors in Older Adults and Response to Vaccination - Year2
    Albert Shaw · 2023 · ImmPort
  52. Synergistic effects of physical and psychological distress on immunesenescence
    Niharika Arora Duggal · 2014 · University of Birmingham Institutional Research Archive (University of Birmingham)