The DOI matches its Crossref record.
Characterization of a human B lymphocyte-specific antigen.
Abstract
A human B lymphocyte-specific antigen (B1) was identified and characterized by the use of a monoclonal antibody. By indirect immunofluorescence, cytotoxicity, and quantitative absorption, B1 was present on approximately 9% of the peripheral blood mononuclear cell fraction and >95% of B cells from blood and lymphoid organs in all individuals tested. Monocytes, resting and activated T cells, null cells, and tumors of T cell and myeloid origin were B1 negative. B1 was distinct from standard B cell phenotypic markers, including Ig and Ia antigen. Removal of the B1 positive population in peripheral blood eliminated all B cells capable or responding to pokeweed mitogen by maturation to Ig-producing cells.
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Metadata
- Authors
- Stashenko, P., Nadler, L. M., Hardy, R., & Schlossman, S. F.
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 1980-10-01
- Volume
- 125
- Issue
- 4
- Pages
- 1678-1685
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W1484629663
- Cited by
- 1,076
- References
- 0
- FWCI
- 14.21
- Type
- journal article
- Language
- en
- Open access
- closed
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- Stashenko, P., Nadler, L. M., Hardy, R., & Schlossman, S. F. (1980). Characterization of a human B lymphocyte-specific antigen. The Journal of Immunology. https://doi.org/10.4049/jimmunol.125.4.1678
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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