The DOI matches its Crossref record.
Thymoma production of T cell growth factor (Interleukin 2).
Abstract
Phorbol-12-myristate-13-acetate stimulates a subline of mouse EL-4 thymoma cells to produce, in vitro, in very high titer, T cell growth factor (Interleukin 2, IL 2). The EL-4-derived IL 2 has the same m.w. (30,000) and isoelectric point heterogeneity (pI 3.8-4.4) as the IL 2 produced by Con A-stimulated spleen cells. In addition, the thymoma-derived IL 2 exhibits the same spectrum of biologic activities as has been reported for spleen cell-derived IL 2.
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Citations
Cited by
Mosmann, T. (1983) · Journal of Immunological Methods · doi:10.1016/0022-1759(83)90303-4 · Cited by 56,104
Truneh, A., Albert, F., Golstein, P., & Schmitt-Verhulst, A.-M. (1985) · Nature · doi:10.1038/313318a0 · Cited by 746
Mazumder, A., & Rosenberg, S. A. (1984) · The Journal of experimental medicine · doi:10.1084/jem.159.2.495 · Cited by 369
Yu, P., Lübben, W., Slomka, H., Gebler, J., Konert, M., Cai, C., Neubrandt, L., Prazeres da Costa, O., Paul, S., Dehnert, S., et al. (2012) · Immunity · doi:10.1016/j.immuni.2012.07.018 · Cited by 192
Arroyo, J., Winchester, E., McLellan, B. S., & Huber, B. T. (1997) · Journal of Virology · doi:10.1128/jvi.71.2.1237-1245.1997 · Cited by 16
Metadata
- Authors
- Farrar, J. J., Fuller-Farrar, J., Simon, P. L., Hilfiker, M. L., Stadler, B. M., & Farrar, W. L.
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 1980-12-01
- Volume
- 125
- Issue
- 6
- Pages
- 2555-2558
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W1576863849
- Cited by
- 481
- References
- 0
- FWCI
- 15.31
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Thymoma production of T cell growth factor (Interleukin 2). https://app.cochat.ai/papers/10.4049/jimmunol.125.6.2555
- The paper
- Farrar, J. J., Fuller-Farrar, J., Simon, P. L., Hilfiker, M. L., Stadler, B. M., & Farrar, W. L. (1980). Thymoma production of T cell growth factor (Interleukin 2). The Journal of Immunology. https://doi.org/10.4049/jimmunol.125.6.2555
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
