The DOI matches its Crossref record.
Coassociation of CD26 (dipeptidyl peptidase IV) with CD45 on the surface of human T lymphocytes
Abstract
In the present report, we demonstrated that modulation of CD26 from T cell surface induced by antiCD26 (1F7) led to enhanced phosphorylation of CD3 zeta tyrosine residues and increased CD4 associated p56lck tyrosine kinase activity. We further showed that CD26 was comodulated on the T cell surface with CD45, a known membrane-linked protein tyrosine phosphatase and that anti-CD26 was capable of precipitating CD45 from T cell lysates. These findings strongly suggest that CD26 may be closely associated with the CD45 protein tyrosine phosphatase on T cell surface and further support the notion that the interaction of CD26 with CD45 results in enhanced tyrosine kinase activity, zeta chain phosphorylation, and T cell activation.
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Citations
Cited by
Lambeir, A.-M., Durinx, C., Scharpé, S., & De Meester, I. (2003) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/713609354 · Cited by 955
Direct Association of Adenosine Deaminase with a T Cell Activation Antigen, CD26
Kameoka, J., Tanaka, T., Nojima, Y., Schlossman, S. F., & Morimoto, C. (1993) · Science · doi:10.1126/science.8101391 · Cited by 507
Self-citationChu, H., Zhou, J., Wong, B. H.-Y., Li, C., Chan, J. F.-W., Cheng, Z.-S., Yang, D., Wang, D., Lee, A. C.-Y., Li, C., et al. (2016) · Journal of Infectious Diseases · doi:10.1093/infdis/jiv380 · Cited by 448
CD45 in human physiology and clinical medicine
Rheinländer, A., Schraven, B., & Bommhardt, U. (2018) · Immunology Letters · doi:10.1016/j.imlet.2018.01.009 · Cited by 294
Pereira, D. A., Gomes, L., El-Cheikh, M. C., & Borojevic, R. (2003) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2003000500003 · Cited by 21
Metadata
- Authors
- Torimoto, Y., Dang, N. H., Vivier, E., Tanaka, T., Schlossman, S. F., & Morimoto, C.
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 1991-10
- Volume
- 147
- Issue
- 8
- Pages
- 2514-2517
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W2098511235
- Cited by
- 206
- References
- 0
- FWCI
- 3.55
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Coassociation of CD26 (dipeptidyl peptidase IV) with CD45 on the surface of human T lymphocytes. https://app.cochat.ai/papers/10.4049/jimmunol.147.8.2514
- The paper
- Torimoto, Y., Dang, N. H., Vivier, E., Tanaka, T., Schlossman, S. F., & Morimoto, C. (1991). Coassociation of CD26 (dipeptidyl peptidase IV) with CD45 on the surface of human T lymphocytes. The Journal of Immunology. https://doi.org/10.4049/jimmunol.147.8.2514
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.