The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Neutrophils Promote Mononuclear Cell Infiltration During Viral-Induced Encephalitis
Abstract
Neutrophils are the first infiltrating cell population to appear within the CNS during infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV). To determine whether neutrophils play a role in limiting acute JHMV infection, mice were depleted of neutrophils. Infection of neutropenic animals resulted in increased levels of virus replication and mortality compared with control mice. Furthermore, neutropenia resulted in significantly reduced mononuclear leukocyte infiltration possibly due to reduced loss of blood brain barrier integrity during acute JHMV infection. These data suggest that infiltrating neutrophils are crucial for limiting virus replication during acute JHMV infection, contribute to the loss of blood brain barrier integrity and play a role in shaping adaptive immunity within the CNS.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Asahi, M., Wang, X., Mori, T., Sumii, T., Jung, J.-C., Moskowitz, M. A., Fini, M. E., & Lo, E. H. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-19-07724.2001 · Cited by 1,004
Cited by
COVID-19: ICU delirium management during SARS-CoV-2 pandemic
Kotfis, K., Williams Roberson, S., Wilson, J. E., Dabrowski, W., Pun, B. T., & Ely, E. W. (2020) · Critical Care · doi:10.1186/s13054-020-02882-x · Cited by 506
Partners in crime: neutrophils and monocytes/macrophages in inflammation and disease
Prame Kumar, K., Nicholls, A. J., & Wong, C. H. Y. (2018) · Cell and Tissue Research · doi:10.1007/s00441-017-2753-2 · Cited by 417
Coronavirus infection of the central nervous system: host–virus stand-off
Bergmann, C. C., Lane, T. E., & Stohlman, S. A. (2006) · Nature Reviews Microbiology · doi:10.1038/nrmicro1343 · Cited by 398
Self-citationThe choroid plexus—a multi-role player during infectious diseases of the CNS
Schwerk, C., Tenenbaum, T., Kim, K. S., & Schroten, H. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00080 · Cited by 147
Mouse Adenovirus Type 1-Induced Breakdown of the Blood-Brain Barrier
Gralinski, L. E., Ashley, S. L., Dixon, S. D., & Spindler, K. R. (2009) · Journal of Virology · doi:10.1128/jvi.00954-09 · Cited by 70
Metadata
- Authors
- Zhou, J., Stohlman, S. A., Hinton, D. R., & Marten, N. W.
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-03
- Volume
- 170
- Issue
- 6
- Pages
- 3331-3336
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W1571502459
- Cited by
- 161
- References
- 1
- FWCI
- 3.17
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Neutrophils Promote Mononuclear Cell Infiltration During Viral-Induced Encephalitis. https://app.cochat.ai/papers/10.4049/jimmunol.170.6.3331
- The paper
- Zhou, J., Stohlman, S. A., Hinton, D. R., & Marten, N. W. (2003). Neutrophils Promote Mononuclear Cell Infiltration During Viral-Induced Encephalitis. The Journal of Immunology. https://doi.org/10.4049/jimmunol.170.6.3331
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
