A role for mammalian target of rapamycin in regulating T cell activation versus anergy

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Items 201–273 of 273

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   J. Malcolm, Mukanthu H. Nyirenda, Jason L. Brown, A. Adrados Planell, L. Campbell, John P. Butcher, David G. Glass, Krystyna Piela, Carl S. Goodyear, Amanda J. Wright et al. · 2023 · Journal of Autoimmunity
8. Translational initiation regulated by ATM in dendritic cells development
   E.-Y. So, Toru Ouchi · 2014 · Cell Death and Disease
9. IL-21 augments rapamycin in expansion of alpha fetoprotein antigen specific stem-cell-like memory T cells in vitro
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10. The eIF4EBP-eIF4E axis regulates CD4+ T cell differentiation through modulation of T cell activation and metabolism
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12. mTORC1 pathway activity biases cell fate choice
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14. Interplay Between Metabolic Sensors and Immune Cell Signaling
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15. Modulating T Cell Phenotype and Function to Treat Hypertension
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16. Mechanisms of self-inactivation in anergic T cells
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17. Translational Control by 4E-BP1/2 Suppressor Proteins Regulates Mitochondrial Biosynthesis and Function during CD8+ T Cell Proliferation
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18. Kinase Suppressor of Ras 1 Is Not Required for the Generation of Regulatory and Memory T Cells
    Marie Le Borgne, Erin L. Filbert, Andréy S. Shaw · 2013 · PLoS ONE
19. Biochemical heterogeneity of T-lymphocytes
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20. Early expression of stem cell-associated genes within the CD8 compartment after treatment with a tumor vaccine
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21. Mechanisms of Immunosuppressive Drugs
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22. Impact of cellular CD71 (transferrin receptor 1) expression in Egyptian acute leukemia: correlation with clinicopathologic features
    Nadia El‐Menshawy, Sherin M. Abd-Aziz, Mohammed A. Ebrahim, Nader Elmalky · 2016 · Comparative Clinical Pathology
23. Tracking Dye‐Independent Approach to Identify and Isolate In Vitro Expanded T Cells
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24. Global profiling of human blood ILC subtypes reveals that NK cells produce homeostatic cytokine amphiregulin and sheds light on HIV-1 pathogenesis
    Yetao Wang, Lawrence M. Lifshitz, Noah J. Silverstein, Esther Mintzer, Kevin Luk, Pam St. Louis, Michael A. Brehm, Scot A. Wolfe, Steven G. Deeks, Jeremy Luban · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
25. Evaluation of mTOR Activity in COPD Patients with Emphysema
    Özge Oral Tapan, Utku Tapan, Tuba Edgünlü, Emrah Doğan · 2022 · Journal of College of Physicians And Surgeons Pakistan
26. Rapamycin Prevents Expansion of Costimulation Blockade-resistant CD8+ Alloreactive Memory Cells following Depletional Induction in Renal Transplant Recipients
    Shu Li, Qimeng Gao, He Xu, Allan D. Kirk · 2024 · The Journal of Immunology
27. Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation.
    Shaimaa Ali Abdelrahman, Mohammed M. Abdelfatah, Akaber T. Keshta · 2022 · PubMed Central
28. PEGylation-based surface engineering of islets with microparticles co-delivery for enhanced engraftment in streptozocin-induced hyperglycemic murine model
    Prakash Sunder Shrestha, Shiva Pathak, Dinesh Chaudhary, Shobha Regmi, Manju Shrestha, Pawan Kumar Raut, Ju-Yeon Kim, Gorka Orive, Ha Rin Kim, Na Kyeong Lee et al. · 2025 · Chemical Engineering Journal
29. The ionotropic AMPA receptor contributes to autoimmunity via altered regulatory T cell differentiation
    Marisa Mitchell-Flack, Makenzie Higgins, Ying Zheng, Ada J Tam, Hana L. Goldschmidt, Hiroshi Nishio, Bian Liu, Christopher Cherry, Michael Patatanian, Richard L. Blosser et al. · 2025 · iScience
30. Novel Agents Targeting Oncogenic Pathways in Lymphoma
    Anas Younes · 2013 · Humana Press eBooks
31. mTOR and its Physiological Impacts-Part II: Immunological Impact
    Tsemay M. Tse, Ping Kwan · 2013
32. Canonical and novel strategies to delay or reverse aging
    Brian C. Gilmour, Linda Hildegard Bergersen, Evandro Fei Fang · 2022 · Elsevier eBooks
33. The pathogenic role of metabolism in Sjögren's syndrome
    Serena Colafrancesco, Edoardo Simoncelli, Roberta Priori, Michele Bombardieri · 2023 · Clinical and Experimental Rheumatology
34. Transcriptional Regulation of T Cell Metabolism Reprograming
    Jinxia Zhang, Guoyu Bi, Yu Xia, Pingfei Li, Xiaofei Deng, Zhengping Wei, Xiang‐Ping Yang · 2017 · Advances in experimental medicine and biology
35. Tumor-Induced Metabolism and T Cells Located in Tumor Environment
    Sara Iranparast, Sanaz Tayebi, Fatemeh Ahmadpour, Bahman Yousefi · 2020 · Current Cancer Drug Targets
36. In Reply
    Salvatore Di Paolo, Domenica Leogrande, Annalisa Teutonico, Elena Ranieri, Marilisa Saldarelli, Loreto Gesualdo, Paolo F. Schena · 2008 · American Journal of Kidney Diseases
37. Decoding mTOR signalling heterogeneity in the tumour microenvironment using multiplexed imaging and graph convolutional networks
    Razan Zuhair, Mark Eastwood, Megan Jones, Amy Rachael Cross, Joanna Hester, Fadi Issa, Fiona Ginty, Heba Sailem · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
38. Dendritic Cells and Coregulatory Signals: Immune Checkpoint Blockade to Stimulate Immunotherapy
    Drew M. Pardoll · 2007 · Elsevier eBooks
39. Regulation of autophagy and mTOR during Semliki Forest virus infection
    Kai Er Eng · 2012 · Figshare
40. The Role of TIPE2 in the Regulation of Inflammation and Tumorigenesis
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41. Current Pathways for Immune Manipulation
    Jason R. Lees, Agnes M. Azimzadeh, Yaozhong Ding, Jiangnan Xu, Jonathan S. Bromberg · 2014
42. Human memory CD8+ T-cells exhibit an intrinsic metabolic advantage as reflected by increased mitochondrial functionality and high glycolytic potential
    Patrick M. Gubser · 2013 · edoc (University of Basel)
43. Intrinsic Mechanisms that Regulate T Cell Homeostasis and Function
    Thomas O’Brien · 2011 · DukeSpace (Duke University)
44. Regulation of calcium signaling and cellular localization of NFAT in CD8+ anergic T cells.
    Mathangi Srinivasan · 2008 · University Libraries (University of Maryland)
45. In vitro generation of human FOXP3+ regulatory T cells
    Ghusoon Abdulhameed Ebrahim Salman Abdulrasool · 2014 · UPT. Syiah Kuala University Library (Syiah Kuala University)
46. OVERCOMING SELF-REACTIVITY THROUGH IMMUNOLOGICAL AND METABOLIC REDOX MODULATION
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47. ROLES OF CD28, INDUCIBLE COSTIMULATOR, AND THE INTERLEUKIN-2 RECEPTOR IN HELPER T CELL MEMORY FORMATION
    Antonio J. Pagán · 2012 · University of Minnesota Digital Conservancy (University of Minnesota)
48. The developmental regulator Gon4-like functions within the transcriptional networks that control B lymphopoiesis and CD4+ T cell responses
    Isaiah L. Hankel · 2011
49. mTOR: Master regulator of T cell differentiation and function
    Jonathan D. Powell · 2009
50. New Agents for Patients with Hodgkin Lymphoma
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51. Dietary manipulation of natural killer cell biology through refeeding of previously calorically restricted mice
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52. The Role of TRAF1 in Signaling Downstream of 4-1BB on CD8 T Cells
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53. Regulation of NFAT5 by signaling pathways involved in osmotic stress responses and cell growth
    Beatriz Morancho Armisen · 2008 · Repositori digital de la UPF (Universitat Pompeu Fabra)
54. Combination Therapies Targeting the PI3K/AKT/mTOR Pathways
    Aung Naing, Gordon Brent Mills, Funda Meric‐Bernstam · 2016 · Cancer drug discovery and develogment/Cancer drug discovery and development
55. The Role of T Cell Tolerance in the Pathogenesis and Treatment of Autoimmune Diseases
    Kyungho Choi · 2013
56. Papel da resposta celular antígeno-específica na tolerância operacional
    Priscila Carmona · 2016
57. A new alternating regimen in metastatic renal cell carcinoma presented through a clinical case
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58. Engineering Biomaterial Properties for T Cell Immunotherapy
    John W. Hickey · 2019
59. Latte: il Tar del Lazio chiama in causa l'Ue
    L. Martirano · 2000 · Informatore agrario
60. T Lymphocytes
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61. Rapamycin and Filgrastim effect on Regulation of Peripheral and Splenic Tissue B- and T-lymphocytes in TAA-Induced Splenic Injury in Rats
    Akaber T. Keshta, Mohammed M. Abdelfatah, Shaimaa Ali Abdelrahman · 2022 · Biochemistry Letters
62. Metabolic changes of lymphocytes in a rat model of autoimmunity
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64. Identification of Novel Signaling Pathways in T Cells Mediated by Protein Kinase C, Carma1, MALT1 and Bcl10
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65. Modulation par le récepteur neurokinine-1du mécanisme d’action des immunosuppresseurs chez les cellules T
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66. Rôle de l’activation des cellules « Natural Killer » par le « missing self » dans la génération de lésions de rejet vasculaire chronique après transplantation d’organe
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67. Etude du métabolisme des lymphocytes T CD4+ Foxp3+ régulateurs à l’homéostasie et dans un contexte inflammatoire
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68. Targeting the metabolic environment to modulate T cell effector function
    Maria I. Matias · 2019 · theses.fr (ABES)
69. Défauts fonctionnels des cellules NK en contexte de stimulation chronique
    Marie Marotel · 2019
70. Modulation de l'activation des lymphocytes T et des réponses anti-tumorales par le fer
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71. PIM1 kinase–regulated cellular metabolism sustains differentiation and function of effector CD8+ T cells during chronic viral infection
    Ashley Kaye Brown, Hongshen Niu, Jian Shen, Yuqi Zhang, Pedro A S Vaz de Castro, Moujtaba Y. Kasmani, Siying Lin, Paytsar Topchyan, Nikita Lavanya Mani, Peter J. Volberding et al. · 2026 · The Journal of Immunology
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73. Hodgkin Lymphoma: From Molecular Pathogenesis to Targeted Therapy
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