A role for mammalian target of rapamycin in regulating T cell activation versus anergy

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Akt Maintains Cell Size and Survival by Increasing mTOR-dependent Nutrient Uptake

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IL-7 Enhances the Survival and Maintains the Size of Naive T Cells

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Prevention of T Cell Anergy by Signaling Through the γ c Chain of the IL-2 Receptor

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The CD28 and CTLA-4 Receptors Associate with the Serine/Threonine Phosphatase PP2A

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Inhibition of Cell Cycle Progression by Rapamycin Induces T Cell Clonal Anergy Even in the Presence of Costimulation

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mTOR integrates amino acid- and energy-sensing pathways

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TOR Signaling

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p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes

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Distinct Signaling Events Downstream of mTOR Cooperate To Mediate the Effects of Amino Acids and Insulin on Initiation Factor 4E-Binding Proteins

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Rapamycin is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling

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Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone

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T Cell Effector Function and Anergy Avoidance Are Quantitatively Linked to Cell Division

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Antagonistic Roles for CTLA-4 and the Mammalian Target of Rapamycin in the Regulation of Clonal Anergy: Enhanced Cell Cycle Progression Promotes Recall Antigen Responsiveness

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Clonal Anergy Is Maintained Independently of T Cell Proliferation1

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Opposing Roles for the Cyclin-Dependent Kinase Inhibitor p27 kip1 in the Control of CD4+ T Cell Proliferation and Effector Function

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Induction of Anergy in Th1 Cells Associated with Increased Levels of Cyclin-Dependent Kinase Inhibitors p21Cip1 and p27Kip1 1

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The Novel Cyclophilin Binding Compound, Sanglifehrin A, Disassociates G1 Cell Cycle Arrest from Tolerance Induction

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Novel Regulatory Mechanisms of mTOR Signaling

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Low-Dose Radiation Plus Rapamycin Promotes Long-Term Bone Marrow Chimerism

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The cyclin‐dependent kinase inhibitors p27Kip1 and p21Cip1 are not essential in T cell anergy

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Untitled work

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mTOR Signaling in Growth, Metabolism, and Disease

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SUnSET, a nonradioactive method to monitor protein synthesis

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mTOR differentially regulates effector and regulatory T cell lineage commitment

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Metabolic Regulation of T Lymphocytes

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Inflammatory T Cell Responses Rely on Amino Acid Transporter ASCT2 Facilitation of Glutamine Uptake and mTORC1 Kinase Activation

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Keeping It All Going—Complement Meets Metabolism

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The mTOR Kinase Determines Effector versus Memory CD8+ T Cell Fate by Regulating the Expression of Transcription Factors T-bet and Eomesodermin

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Changes in Nutritional Status Impact Immune Cell Metabolism and Function

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Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase

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Biologically Inspired Design of Nanoparticle Artificial Antigen-Presenting Cells for Immunomodulation

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Regulation of T Helper Cell Fate by TCR Signal Strength

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Tolerogenic Nanoparticles Induce Antigen-Specific Regulatory T Cells and Provide Therapeutic Efficacy and Transferrable Tolerance against Experimental Autoimmune Encephalomyelitis

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Nutrient Sensing via mTOR in T Cells Maintains a Tolerogenic Microenvironment

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mTOR at the crossroads of T cell proliferation and tolerance

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microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells

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