The DOI matches its Crossref record.
The Formation of Circulating Antibody in the Splenec Tomized Human Being Following Intravenous Injection of Heterologous Erythrocytes
Abstract
Summary: Sixteen control and fourteen splenectomized patients were given a single intravenous injection of 1.0 ml of a 2.0 per cent suspension of washed sheep erythrocytes. All controls responded with a significant rise in antibody titer between nine to fourteen days after the injection. Thirteen out of fourteen splenectomized patients failed to respond with a significant rise in antibody titer during this same time interval. Splenectomy had been performed eight days to forty months prior to immunization. The possible significance of these findings is discussed in terms of three syndromes: acquired hemolytic anemia, idiopathic thrombocytopenia, and erythroblastosis foetalis.
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Citations
Cited by
Functional Asplenia in Sickle-Cell Anemia
Pearson, H. A., Spencer, R. P., & Cornelius, E. A. (1969) · New England Journal of Medicine · doi:10.1056/nejm196910232811703 · Cited by 425
Postsplenectomy Sepsis and Mortality in Adults
Schwartz, P. E. (1982) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1982.03330180039029 · Cited by 296
Host Defense Against Streptococcus pneumoniae: The Role of the Spleen
Wara, D. W. (1981) · Clinical Infectious Diseases · doi:10.1093/clinids/3.2.299 · Cited by 84
Metadata
- Authors
- Rowley, D. A.
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 1950-11-01
- Volume
- 65
- Issue
- 5
- Pages
- 515-521
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W1602112706
- Cited by
- 199
- References
- 0
- FWCI
- 3.85
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The Formation of Circulating Antibody in the Splenec Tomized Human Being Following Intravenous Injection of Heterologous Erythrocytes. https://app.cochat.ai/papers/10.4049/jimmunol.65.5.515
- The paper
- Rowley, D. A. (1950). The Formation of Circulating Antibody in the Splenec Tomized Human Being Following Intravenous Injection of Heterologous Erythrocytes. The Journal of Immunology. https://doi.org/10.4049/jimmunol.65.5.515
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
