Myocarditis mimicking acute coronary syndrome following influenza B virus infection: a case report
Open accessAbstract
We present a notable case of a 15-year-old male infected with influenza B virus who showed the clinical manifestations of myocardial ischemia. He was admitted to our hospital with sudden chest pain. He had febrile illness for the past 2 days. Rapid antigen test for influenza revealed positive influenza B virus antigen. The initial electrocardiogram showed elevation of the ST-segments in leads II, II, aVF and reciprocal depression in leads V1 and V2. Serum test showed elevation of creatine kinase and troponin T. Gadlinium-enchanced magnetic resonance imaging, Tl-201 and I-123 beta-methyl-p-iodephenyl-pentadecanoic acid scintigram, coronary angiography revealed no abnormality. Follow-up electrocardiogram showed ST-segment change improvement over the course. Myocarditis associated with influenza B virus seemed to be caused by endothelial impairment and disturbance of microcirculation rather than direct injury to cardiac myocytes.
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There are a few reports of sudden unexpected cardiac arrest or rapidly developing manifestations suggestive of myocardial ischemia in previously healthy children infected with influenza B virus.
“there are a few reports of sudden unexpected cardiac arrest or rapidly developing manifestations suggestive of myocardial ischemia in previously healthy children infected with influenza B virus [38,39]”
From Myocardial Injury and Bacterial Pneumonia Contribute to the Pathogenesis of Fatal Influenza B Virus Infection (2012) · cites this paper as [39]
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- Authors
- Muneuchi, J., Kanaya, Y., Takimoto, T., Hoshina, T., Kusuhara, K., & Hara, T.
- Affiliations
- Kyushu University (JP)
- Corresponding author
- Muneuchi, Jun
- Venue
- Cases Journal
- Published
- 2009
- Volume
- 2
- Issue
- 1
- Pages
- 6809
- ISSN
- 1757-1626 (ISSN-L)
- PMC
- PMC2740055
- OpenAlex
- W2169067064
- Cited by
- 15
- References
- 15
- Citations by year
- 2026: 2 · 2024: 1 · 2022: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 2 · 2013: 2 · 2012: 1
- FWCI
- 0.87
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- Cases Journal (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Viral Infections and Immunology Research
- Health Sciences › Medicine › Epidemiology › Influenza Virus Research Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Takotsubo Cardiomyopathy and Associated Phenomena
- Keywords
- influenza B, myocarditis, acute coronary syndrome mimic, myocardial ischemia, ST-segment elevation, troponin T, creatine kinase, gadolinium-enhanced MRI, coronary angiography, endothelial dysfunction, microcirculation, adolescents
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