Cited by 216Obsessive-Compulsive Spectrum DisordersAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychoanalysis and Psychopathology Research

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Treatment Response, Symptom Remission, and Wellness in Obsessive-Compulsive Disorder

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Farris, Samantha G., McLean, Carmen P., Van Meter, Page E., Simpson, Helen Blair, Foa, Edna B.·2013·The Journal of Clinical Psychiatry

DOI 10.4088/jcp.12m07789PMC PMC3959901

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Abstract

BACKGROUND: Obsessive-compulsive disorder (OCD) is defined both by intrusive, unwanted thoughts, images, or impulses and by repetitive behavioral or mental acts that are often performed to try to alleviate anxiety. The ultimate goal of treatment for OCD is to reduce the symptoms as well as help patients achieve "wellness." Currently, however, there are no widely accepted, empirically supported criteria for determining wellness in OCD. METHOD: Building on previous research, the current study examined the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score that most reliably identified patients who responded to treatment, those who achieved symptom remission, and those who achieved wellness. The current study pooled data from 4 randomized controlled OCD treatment trials (N = 288), which took place between 1990 and 2011 at 2 academic sites. Participants (mean age = 36.8 years) had a primary diagnosis of DSM-IV-TR OCD (mean Y-BOCS score = 25.9). RESULTS: Signal detection analyses showed that a pretreatment-to-posttreatment reduction of ≥ 35% on the Y-BOCS was most predictive of treatment response as defined by the Clinical Global Impressions (CGI)-Improvement scale. A posttreatment Y-BOCS score of ≤ 14 was the best predictor of symptom remission, whereas a score of ≤ 12 was the best predictor of wellness, as defined by symptom remission (defined by the CGI-Severity scale), good quality of life (as measured by the Quality of Life Enjoyment and Satisfaction Questionnaire), and a high level of adaptive functioning (as assessed by the Social Adjustment Scale-Self-Report). Because efficiency (0.86) and specificity (0.88) were highest at the cutoff of ≤ 12, this cutoff score was determined to be the best indicator of wellness. CONCLUSIONS: The present findings support the convergent validity of the Y-BOCS with other measures of well-being (quality of life, adaptive functioning) and highlight the utility of a Y-BOCS score ≤ 12 as a solo indicator of wellness in outcome studies. The use of empirically supported criteria for defining wellness in OCD is recommended to facilitate comparisons across treatment outcome studies and to inform clinical treatment planning. TRIAL REGISTRATION: Pooled data analyzed in this study were from 4 clinical trials, 3 of which are registered at ClinicalTrials.gov (identifiers: NCT00045903, NCT00389493, NCT00316316).

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The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability
Goodman, W. K. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810110048007 · Cited by 7,712
Untitled work
(2005) · PubMed · Cited by 7,011
The Yale-Brown Obsessive Compulsive Scale: II. Validity
Goodman, W. K. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810110054008 · Cited by 2,799
The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication
Ruscio, A. M., Stein, D. J., Chiu, W. T., & Kessler, R. C. (2010) · Molecular Psychiatry · doi:10.1038/mp.2008.94 · Cited by 2,771
Untitled work
(1993) · PubMed · Cited by 1,900
Assessment of social adjustment by patient self report.
Weissman, M. M. (1976) · Archives of General Psychiatry · doi:10.1001/archpsyc.1976.01770090101010 · Cited by 1,782
Randomized, placebo-controlled trial of exposure and ritual prevention, clomipramine, and their combination in the treatment of obsessive–compulsive disorder
Foa, E. B., Liebowitz, M. R., Kozak, M. J., Davies, S., Campeas, R., Franklin, M. E., Huppert, J. D., Kjernisted, K., Rowan, V., Schmidt, A. B., et al. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.1.151 · Cited by 1,048
Self-citation
Quality-of-Life Impairment in Depressive and Anxiety Disorders
Rapaport, M. H., Clary, C., Fayyad, R., & Endicott, J. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.6.1171 · Cited by 914
Methods for defining and determining the clinical significance of treatment effects: Description, application, and alternatives.
Jacobson, N. S., Roberts, L. J., Berns, S. B., & McGlinchey, J. B. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.67.3.300 · Cited by 853
Methods for defining and determining the clinical significance of treatment effects: description, application and alternatives
Jacobson, N. S., Roberts, L. J., Berns, S. B., & McGlinchey, J. B. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.67.3.300 · Cited by 853

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[33]Fischer J Corcoran K Measures for Clinical Practice 2 NY Free Press 1994

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Rickelt, J. (2022) · Research Publications (Maastricht University) · doi:10.26481/dis.20221215jr
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Kayser, R. R., & Simpson, H. B. (2024) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615375523.as52 · Cited by 1
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Authors: Farris, S. G., McLean, C. P., Van Meter, P. E., Simpson, H. B., & Foa, E. B.
Affiliations: University of Pennsylvania (US)
New York State Psychiatric Institute (US)
Corresponding author: Farris, Samantha G.
ORCID: Farris, Samantha G.
McLean, Carmen P.
Simpson, Helen Blair
Foa, Edna B.
Venue: The Journal of Clinical Psychiatry
Publisher: Physicians Postgraduate Press, Inc
Published: 2013-07-15
Volume: 74
Issue: 07
Pages: 685-690
ISSN: 0160-6689 (ISSN-L)
DOI: 10.4088/jcp.12m07789
PMC: PMC3959901
OpenAlex: W1979431943
Cited by: 216
References: 33
Citations by year: 2026: 17 · 2025: 16 · 2024: 19 · 2023: 10 · 2022: 20 · 2021: 23 · 2020: 21 · 2019: 21 · 2018: 11 · 2017: 10 · 2016: 22 · 2015: 16 · 2014: 9 · 2013: 1
FWCI: 17.80
Type: journal article
Language: en
Open access: green
europepmc.org
Locations: The Journal of Clinical Psychiatry (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Mental Health (MH-04504-19, K24MH091555, R01MH045404, R34MH071570, K23MH001907, K23 MH-01907, MH-04504-05A2, R01MH045436, MH-04504-10A1, R01MH-45436)
Topics: Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
Keywords: obsessive-compulsive disorder, treatment response, symptom remission, wellness, Yale-Brown Obsessive Compulsive Scale, cut-off values, quality of life, adaptive behavior, convergent validity, treatment outcome measures, signal detection analysis, Clinical Global Impression Scale, treatment planning
MeSH terms: Adaptation, Psychological, Adult, Female, Health Status Indicators, Humans, Male, Obsessive-Compulsive Disorder, Psychiatric Status Rating Scales, Psychotropic Drugs, Quality of Life, Remission Induction, Research Design, Sensitivity and Specificity, Reproducibility of Results, Cognitive Behavioral Therapy, Treatment Outcome, Diagnostic and Statistical Manual of Mental Disorders

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Treatment Response, Symptom Remission, and Wellness in Obsessive-Compulsive Disorder

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