Don't Ask, Don't Tell, but Benzodiazepines Are Still the Leading Treatments for Anxiety Disorder: (Brainstorms)
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Article AbstractModern guidelines for psychopharmacologic treatment of anxiety disorders have evolved from recommending GABAergic (gammaaminobutryic acid) benzodiazepines to recommending serotonergic agents for first-line use. This trend, along with adverse publicity about the dependence potential of benzodiazepines, might lead one to suspect that benzodiazepines, once prominent in the 1980s but now generic and often disparaged, must have significantly declined in use. Not so. In fact, benzodiazepines are still more widely prescribed than antidepressants for the treatment of anxiety disorders (Table 1), and alprazolam is the single most commonly prescribed agent for mood and anxiety disorders(Table 2).
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Benzodiazepines are effective in the treatment of anxiety disorders.
“BZDs are effective in the treatment of anxiety disorders [2,3,4] and insomnia [5,6].”
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- Authors
- Stahl, S. M.
- Corresponding author
- Stahl, Stephen M.
- ORCID
- Stahl, Stephen M.
- Venue
- The Journal of Clinical Psychiatry
- Publisher
- Physicians Postgraduate Press, Inc
- Published
- 2002-09-15
- Volume
- 63
- Issue
- 9
- Pages
- 756-757
- ISSN
- 0160-6689 (ISSN-L)
- OpenAlex
- W101037913
- Cited by
- 88
- References
- 7
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 5 · 2022: 6 · 2021: 3 · 2020: 4 · 2019: 3 · 2018: 6 · 2017: 5 · 2016: 5 · 2015: 2 · 2014: 7 · 2013: 3 · 2012: 2
- FWCI
- 6.72
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Journal of Clinical Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- benzodiazepines, anxiety disorders, alprazolam, antidepressants, psychopharmacologic treatment, prescribing patterns, GABAergic agents, serotonergic agents, benzodiazepine dependence, treatment guidelines
- MeSH terms
- Alprazolam, Antidepressive Agents, Anxiety Disorders, Drug Therapy, Combination, Humans, Practice Patterns, Physicians', Anti-Anxiety Agents, Treatment Outcome, Selective Serotonin Reuptake Inhibitors, Practice Guidelines as Topic, Serotonin Agents, Sertraline
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