Cited by 243Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMental Health Treatment and AccessHealth and Well-being Studies

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Anxiety, Depression, and Quality of Life in Primary Care Patients

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Brenes, Gretchen A.·2007·The Primary Care Companion to The Journal of Clinical Psychiatry

DOI 10.4088/pcc.v09n0606PMC PMC2139931

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Abstract

BACKGROUND: Anxiety and depressive disorders have a significant and negative impact on quality of life. However, less is known about the effects of anxiety and depressive symptoms on quality of life. The purpose of this study was to examine the impact of anxiety and depressive symptoms on emotional and physical functioning, the effects of anxiety symptoms on functioning independent of depressive symptoms, and the effects of depressive symptoms on functioning independent of anxiety symptoms. METHOD: Participants included 919 patients, recruited from 2 university-affiliated primary care clinics between May 2004 and September 2006, who completed self-report measures of anxiety symptoms, depressive symptoms, and quality of life. RESULTS: Almost 40% of the sample reported anxiety symptoms and 30% reported depressive symptoms. In both unadjusted and adjusted models, anxiety and depressive symptoms were significantly associated with all domains of quality of life. When anxiety and depressive symptoms were added simultaneously, both remained significant. As the severity of anxiety or depressive symptoms increased, quality of life decreased. Furthermore, patients with moderate to severe anxiety or depressive symptoms had greater impairments in most quality of life domains than patients with acute myocardial infarction, congestive heart failure, or diabetes. CONCLUSION: Detection and treatment of anxiety and depressive symptoms in the primary care setting should be emphasized.

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Authors: Brenes, G. A.
Affiliations: Wake Forest University Health Sciences (US)
Corresponding author: Brenes, Gretchen A.
ORCID: Brenes, Gretchen A.
Venue: The Primary Care Companion to The Journal of Clinical Psychiatry
Publisher: Physicians Postgraduate Press, Inc
Published: 2007-12-14
Volume: 09
Issue: 06
Pages: 437-443
ISSN: 1523-5998 (ISSN-L)
DOI: 10.4088/pcc.v09n0606
PMC: PMC2139931
OpenAlex: W2076461598
Cited by: 243
References: 40
Citations by year: 2026: 8 · 2025: 26 · 2024: 24 · 2023: 35 · 2022: 29 · 2021: 21 · 2020: 13 · 2019: 21 · 2018: 16 · 2017: 10 · 2016: 7 · 2015: 4 · 2014: 8 · 2013: 4 · 2012: 5
FWCI: 3.85
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: The Primary Care Companion to The Journal of Clinical Psychiatry (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Mental Health (K23MH065281)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Social Sciences › Psychology › Clinical Psychology › Health and Well-being Studies
Keywords: anxiety symptoms, depressive symptoms, quality of life, primary care patients, emotional functioning, physical function, comorbidities, symptom severity, acute myocardial infarction, congestive heart failure, diabetes mellitus, mental health screening

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Anxiety, Depression, and Quality of Life in Primary Care Patients

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