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Anxiety, Depression, and Quality of Life in Primary Care Patients
Open accessAbstract
BACKGROUND: Anxiety and depressive disorders have a significant and negative impact on quality of life. However, less is known about the effects of anxiety and depressive symptoms on quality of life. The purpose of this study was to examine the impact of anxiety and depressive symptoms on emotional and physical functioning, the effects of anxiety symptoms on functioning independent of depressive symptoms, and the effects of depressive symptoms on functioning independent of anxiety symptoms. METHOD: Participants included 919 patients, recruited from 2 university-affiliated primary care clinics between May 2004 and September 2006, who completed self-report measures of anxiety symptoms, depressive symptoms, and quality of life. RESULTS: Almost 40% of the sample reported anxiety symptoms and 30% reported depressive symptoms. In both unadjusted and adjusted models, anxiety and depressive symptoms were significantly associated with all domains of quality of life. When anxiety and depressive symptoms were added simultaneously, both remained significant. As the severity of anxiety or depressive symptoms increased, quality of life decreased. Furthermore, patients with moderate to severe anxiety or depressive symptoms had greater impairments in most quality of life domains than patients with acute myocardial infarction, congestive heart failure, or diabetes. CONCLUSION: Detection and treatment of anxiety and depressive symptoms in the primary care setting should be emphasized.
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“Delaying treatment can lead to negative consequences for those with anxiety and depression (Brenes, 2007; Hawton and van Heeringen, 2009).”
From Translating the Intention to Seek Treatment into Action: Does Symptom Monitoring Make a Difference? Results from a Randomized Controlled Trial (2019) · cites this paper as Brenes, 2007
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Cites
An inventory for measuring clinical anxiety: Psychometric properties.
Beck, A. T., Epstein, N., Brown, G., & Steer, R. A. (1988) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.56.6.893 · Cited by 14,407
Kessler, R. C., Chiu, W. T., Demler, O., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.617 · Cited by 12,052
Cognitive Therapy for Depression
(2012) · PsycEXTRA Dataset · doi:10.1037/e675542012-001 · Cited by 9,678
Cognitive Therapy of Depression
HOLLON, S. D., & BECK, A. T. (1979) · Cognitive-Behavioral Interventions · doi:10.1016/b978-0-12-404480-7.50012-5 · Cited by 4,685
The functioning and well-being of depressed patients. Results from the Medical Outcomes Study
Wells, K. B. (1989) · JAMA · doi:10.1001/jama.262.7.914 · Cited by 2,826
Prevalence and Treatment of Mental Disorders, 1990 to 2003
Kessler, R. C., Demler, O., Frank, R. G., Olfson, M., Pincus, H. A., Walters, E. E., Wang, P., Wells, K. B., & Zaslavsky, A. M. (2005) · New England Journal of Medicine · doi:10.1056/nejmsa043266 · Cited by 1,910
Quality of Life in Individuals With Anxiety Disorders
Mendlowicz, M. V., & Stein, M. B. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.5.669 · Cited by 955
The impact of psychiatric disorders on work loss days
Kessler, R. C., & Frank, R. G. (1997) · Psychological Medicine · doi:10.1017/s0033291797004807 · Cited by 716
Prevalence and Treatment of Mental Disorders
MacKenzie, T. D., Kolpak, S. J., & Mehler, P. S. (2005) · New England Journal of Medicine · doi:10.1056/nejmc051936 · Cited by 650
Lenze, E. J., Rogers, J. C., Martire, L. M., Mulsant, B. H., Rollman, B. L., Dew, M. A., Schulz, R., & Reynolds, C. F. (2001) · The American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200105000-00004 · Cited by 593
Bartels, S. J., Coakley, E. H., Zubritsky, C., Ware, J. H., Miles, K. M., Areán, P. A., Chen, H., Oslin, D. W., Llorente, M. D., Costantino, G., et al. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.8.1455 · Cited by 417
Talbott, J. A. (2006) · Yearbook of Psychiatry and Applied Mental Health · doi:10.1016/s0084-3970(08)70124-5 · Cited by 394
de BEURS, E., BEEKMAN, A. T. F., van BALKOM, A. J. L. M., DEEG, D. J. H., van DYCK, R., & van TILBURG, W. (1999) · Psychological Medicine · doi:10.1017/s0033291799008351 · Cited by 378
Sareen, J., Jacobi, F., Cox, B. J., Belik, S.-L., Clara, I., & Stein, M. B. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.19.2109 · Cited by 361
High prevalence of mental disorders in primary care
Ansseau, M., Dierick, M., Buntinkx, F., Cnockaert, P., De Smedt, J., Van Den Haute, M., & Vander Mijnsbrugge, D. (2004) · Journal of Affective Disorders · doi:10.1016/s0165-0327(02)00219-7 · Cited by 352
Roy-Byrne, P. P., Craske, M. G., Stein, M. B., Sullivan, G., Bystritsky, A., Katon, W., Golinelli, D., & Sherbourne, C. D. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.3.290 · Cited by 314
Prevalence of Anxiety, Depression, and Substance Use Disorders in an Urban General Medicine Practice
Olfson, M. (2000) · Archives of Family Medicine · doi:10.1001/archfami.9.9.876 · Cited by 271
Wells, K. B., & Sherbourne, C. D. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.10.897 · Cited by 234
Subthreshold Psychiatric Symptoms in a Primary Care Group Practice
Olfson, M. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830100026004 · Cited by 227
Rollman, B. L., Belnap, B. H., Mazumdar, S., Houck, P. R., Zhu, F., Gardner, W., Reynolds, C. F., Schulberg, H. C., & Shear, M. K. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.12.1332 · Cited by 197
Quality of Care for Primary Care Patients With Anxiety Disorders
Stein, M. B., Sherbourne, C. D., Craske, M. G., Means‐Christensen, A. J., Bystritsky, A., Katon, W. J., Sullivan, G., & Roy‐Byrne, P. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.12.2230 · Cited by 189
Sherbourne, C. D. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830100035005 · Cited by 188
Persistently poor outcomes of undetected major depression in primary care
ROST, K. M., Zhang, M., Fortney, J. C., Smith, J. L., Coyne, J., & Smith, G. R. (1998) · General Hospital Psychiatry · doi:10.1016/s0163-8343(97)00095-9 · Cited by 187
The Influence of Anxiety on the Progression of Disability
Brenes, G. A., Guralnik, J. M., Williamson, J. D., Fried, L. P., Simpson, C. F., Simonsick, E. M., & Penninx, B. W. J. H. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2005.53007.x · Cited by 177
Self-citationPsychometric evaluation of the Beck Anxiety Inventory with older medical patients.
Wetherell, J. L., & Areán, P. A. (1997) · Psychological Assessment · doi:10.1037/1040-3590.9.2.136 · Cited by 162
Goldney, R. D., Fisher, L. J., Dal Grande, E., & Taylor, A. W. (2004) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-004-0745-5 · Cited by 161
Recognition and Treatment of Depression and Anxiety in Patients With Acute Myocardial Infarction
Huffman, J. C., Smith, F. A., Blais, M. A., Beiser, M. E., Januzzi, J. L., & Fricchione, G. L. (2006) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2006.02.033 · Cited by 137
Anxiety, depression and disability across the lifespan
Brenes, G. A., Penninx, B. W. J. H., Judd, P. H., Rockwell, E., Sewell, D. D., & Wetherell, J. L. (2008) · Aging & Mental Health · doi:10.1080/13607860601124115 · Cited by 125
Self-citationQuality of Care for Primary Care Patients With Depression in Managed Care
Wells, K. B. (1999) · Archives of Family Medicine · doi:10.1001/archfami.8.6.529 · Cited by 120
Morbilidad psiquiátrica en pacientes mayores de 18 años
King, M. (n.d.) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 112
Persistent depressive symptoms lower aspirin adherence after acute coronary syndromes
Rieckmann, N., Kronish, I. M., Haas, D., Gerin, W., Chaplin, W. F., Burg, M. M., Vorchheimer, D., & Davidson, K. W. (2006) · American Heart Journal · doi:10.1016/j.ahj.2006.05.014 · Cited by 111
Depressive Symptoms and Adherence to Asthma Therapy After Hospital Discharge
Smith, A. W., Krishnan, J. A., Bilderback, A. L., Riekert, K. A., Rand, C. S., & Bartlett, S. J. (2006) · CHEST Journal · doi:10.1378/chest.130.4.1034 · Cited by 102
Levkoff, S. E., Chen, H., Coakley, E. H., McDonel, E. C., Oslin, D. W., Katz, I. R., Bartels, S. J., Maxwell, J., Olsen, E. J., Miles, K. M., et al. (2004) · Journal of Aging and Health · doi:10.1177/0898264303260390 · Cited by 88
Importance of Subsyndromal Symptoms of Depression in Elderly Patients
Chopra, M. P., Zubritsky, C. D., Knott, K. A., Have, T. T., Hadley, T. R., Coyne, J. C., & Oslin, D. W. (2005) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200507000-00008 · Cited by 84
The nature and prevalence of anxiety disorders in primary care
Nisenson, L. G., Pepper, C. M., Schwenk, T. L., & Coyne, J. C. (1998) · General Hospital Psychiatry · doi:10.1016/s0163-8343(97)00096-0 · Cited by 73
Dalessandro, M., Conti, C. M., Gambi, F., Falasca, K., Doyle, R., Conti, P., Caciagli, F., Fulcheri, M., & Vecchiet, J. (2007) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e31802f0dd1 · Cited by 54
Anxiety Disorders Among Older Primary Care Patients
Stanley, M. A., ROBERTS, R. E., Bourland, S. L., & Novy, D. M. (2001) · Journal of Clinical Geropsychology · doi:10.1023/a:1009533621832 · Cited by 51
Treating panic disorder in primary care: a collaborative care intervention.
Craske, M., Roy-Byrne, P., Stein, M., Donald-Sherbourne, C., Bystritsky, A., Katon, W., & Sullivan, G. (2002) · General Hospital Psychiatry · doi:10.1016/s0163-8343(02)00174-3 · Cited by 48
Scared to death: results from the health, aging, and body composition study
Brenes, G. A., Kritchevsky, S. B., Mehta, K. M., Yaffe, K., Simonsick, E. M., Ayonayon, H. N., Rosano, C., Rubin, S. M., Satterfield, S., & Penninx, B. W. J. H. (2007) · The American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e31802e21f0 · Cited by 30
Self-citationFerguson, C. J., Stanley, M. A., Souchek, J., & Kunik, M. E. (2005) · Depression and Anxiety · doi:10.1002/da.20136 · Cited by 22
Flagged first, then by citations
Research works printed but not linked: 1
- Ware JE Jr, Kosinski M, and Gandek B. SF-36 Health Survey: Manual & Interpretation Guide. Lincoln, RI: Quality Metric Inc. 1993 [Google Scholar]
Cited by
Sorted by citations
Smith, L., Jacob, L., Yakkundi, A., McDermott, D., Armstrong, N. C., Barnett, Y., López-Sánchez, G. F., Martin, S., Butler, L., & Tully, M. A. (2020) · Psychiatry Research · doi:10.1016/j.psychres.2020.113138 · Cited by 385
Gulliver, A., Griffiths, K. M., Christensen, H., & Brewer, J. L. (2012) · BMC Psychiatry · doi:10.1186/1471-244x-12-81 · Cited by 342
“depression or anxiety [15].”
Postpartum psychiatric disorders
Meltzer-Brody, S., Howard, L. M., Bergink, V., Vigod, S., Jones, I., Munk-Olsen, T., Honikman, S., & Milgrom, J. (2018) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2018.22 · Cited by 357
The relationship between chronotype and depressive symptoms: a meta-analysis
Au, J., & Reece, J. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.04.021 · Cited by 297
Arrieta, J., Aguerrebere, M., Raviola, G. J., Flores, H., Elliott, P. F., Espinosa, A., Reyes, A., Ortiz‐Panozo, E., Rodriguez-Gutierrez, E. G., Mukherjee, J. S., et al. (2017) · Journal of Clinical Psychology · doi:10.1002/jclp.22390 · Cited by 261
Metadata
- Authors
- Brenes, G. A.
- Affiliations
- Wake Forest University Health Sciences (US)
- Corresponding author
- Brenes, Gretchen A.
- ORCID
- Brenes, Gretchen A.
- Venue
- The Primary Care Companion to The Journal of Clinical Psychiatry
- Publisher
- Physicians Postgraduate Press, Inc
- Published
- 2007-12-14
- Volume
- 09
- Issue
- 06
- Pages
- 437-443
- ISSN
- 1523-5998 (ISSN-L)
- PMC
- PMC2139931
- OpenAlex
- W2076461598
- Cited by
- 243
- References
- 40
- Citations by year
- 2026: 8 · 2025: 26 · 2024: 24 · 2023: 35 · 2022: 29 · 2021: 21 · 2020: 13 · 2019: 21 · 2018: 16 · 2017: 10 · 2016: 7 · 2015: 4 · 2014: 8 · 2013: 4 · 2012: 5
- FWCI
- 3.85
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- The Primary Care Companion to The Journal of Clinical Psychiatry (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (K23MH065281)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Health and Well-being Studies
- Keywords
- anxiety symptoms, depressive symptoms, quality of life, primary care patients, emotional functioning, physical function, comorbidities, symptom severity, acute myocardial infarction, congestive heart failure, diabetes mellitus, mental health screening
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