Impact of psoriasis on quality of life in Iran
Open accessAbstract
BACKGROUND: The Psoriasis Disability Index (PDI) questionnaire is a widely used instrument to measure psychological morbidity in plaque-type psoriasis patients. AIMS: This study aimed to validate the Persian version of the PDI and to evaluate the impact of psoriasis on quality of life (QOL). METHODS: The English language version of the PDI was translated into Persian (Iranian official language) and was used in this study. The questionnaire was administered to a consecutive sample of 125 chronic plaque-type psoriasis patients and statistical analysis was performed to evaluate the impact of psoriasis on QOL. The other health-related QOL assessment tool included the Persian version of the Dermatology Life Quality Index (DLQI). RESULTS: Overall, 125 patients who had received the PDI and DLQI completed all the questions. Reliability analysis showed a satisfactory result (Cronbach's a coefficient=0.92 and 0.79 for PDI and DLQI, respectively). There was a strong statistical correlation between mean PDI and DLQI scores, with mean Psoriasis Area and Severity Index (PASI) (P=0.005 and 0.02). Also, a significant correlation coefficient existed between DLQI and PDI (r=0.94). The higher the PASI index, the higher the PDI and DLQI scores, which indicated greater impact on QOL. In the patients with lesions on visible exposed skin areas, the correlation was statistically significant (P=0.002 and 0.01). CONCLUSION: The Persian PDI is an acceptable, reliable and valid measure of psychological distress, with more suitable content validity than DLQI for assessment of impact of psoriasis on QOL among psoriasis patients. Data provided may improve the physicians' awareness of the importance of the patients' QOL.
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Clinical severity measured by clinicians using formal grading scales does not always correlate with patients' perceptions of severity, and the discrepancy appears disease-specific.
“clinical severity, as measured by clinicians using formal grading scales, does not always correlate with patients’ perceptions of their condition’s severity. The discrepancy appears to be disease-specific.”
From Global Burden of Skin Disease: Inequities and Innovations (2017) · cites this paper as [18]
Clinical severity of psoriasis correlates more to patient perception due to the presence of comorbid psoriatic arthritis.
“The clinical severity of psoriasis correlates more to patient perception due to the presence of comorbid psoriatic arthritis”
From Global Burden of Skin Disease: Inequities and Innovations (2017) · cites this paper as [18]
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- [2]2. Calman KC. Quality of life in cancer patients-hypothesis. J Med Ethics 1984;10:124-7.
- [3]3. Price P , Harding KG. Defining quality of life. J Wound Care 1993;2:304-6.
- [4]4. De Korte J, Sprangers MA, Mombers FM, Bos JD. Quality of life in patients with psoriasis: A systematic literature review. J Invest Dermatol Symp Proc 2004;9:140-7.
- [5]5. Fortune DG, Main CJ, O Sullivan TM, Griffiths CE. Quality of life in patients with psoriasis: The contribution of clinical variables and psoriasis-specific stress. Br J Dermatol 1997;137:766-70.
- [6]6. Krueger G, Koo J, Lebwohl M, Menter A, Stern RS, Rolstad T. Indian J Dermatol Venereol Leprol | March-April 2009 | Vol 75 | Issue 2 - The impact of psoriasis on quality of life: Results of a 1998 National Psoriasis Foundation patient-membership survey. Arch Dermatol 2001;137:280-4.
- [7]7. Rapp SR, Feldman SR, Exum ML, Fleischer AB, Reboussin DM. Psoriasis causes as much disability as other major medical diseases. J Am Acad Dermatol 1999;41:401-7.
- [8]8. Fried RG, Friedman S, Paradis C, Hatach M, Lynfield Y, Duncanson C, et al . Trivial or terrible? The psychosocial impact of psoriasis. Int J Dermatol 1995;34:101-5.
- [9]9. Akay A, Pekcanlar A, Bozdag KE, Altintas L, Karaman A. Assessment of depression in subjects with psoriasis vulgaris and lichen planus. J Eur Acad Dermatol Venereol 2002;16:34752.
- [10]10. Gupta MA, Schork NJ, Gupta AK, Kirkby S, Ellis CN. Suicidal ideation in psoriasis. Int J Dermatol 1993;32:188-90.
- [11]11. Heydendael VM, de Borgie CA, Spuls PI, Bossuyt PM, Bos JD, DeRie MA. The burden of psoriasis is not determined by disease severity only. J Invertig Dermatol Symp Proc 2004;9:131-5.
- [12]12. Slevin ML, Plant H, Lynch D, Drinkwater J, Gregory WM. Who should measure quality of life, the doctor or patient? Br J Cancer 1988;57:109-12.
- [13]13. Marks R, Barton SP , Shuttleworth D, Finlay AY. Assessment of disease progress in psoriasis. Arch Dermatol 1989;125:23540.
- [14]14. Finlay AY, Khan GK. Dermatology Life Quality Index (DLQI): A simple practical measure for routine clinical use. Clin Exp Dermatol 1994;19:210-6.
- [15]15. Aghaei S, Sodaifi M, Jafari P , Mazharinia N, Finlay AY. DLQI scores in vitiligo: reliability and validity of the Persian version. BMC Dermatol 2004;4:8.
- [16]16. Nunnally JC. Psychometric theory. New York: McGraw-Hill; 1978.
- [18]18. Finlay AY, Kelly SE. Psoriasis: An index of disability. Clin Exp Dermatol 1987;12:8-11.
- [19]19. Finlay AY, Coles EC. The effect of severe psoriasis on the quality of life of 369 patients. Br J Dermatol 1995;132:23644.
- [20]20. Finlay AY, Khan GK, Luscombe DK, Salek MS. Validation of sickness impact profile and psoriasis disability index in psoriasis. Br J Dermatol 1990;123:751-6.
- [21]21. Salek MS, Finlay AY. Cyclosporin improves quality of life in psoriasis: Does this matter? Br J Dermatol 1993;129:32.
- [22]22. Root S, Kent G, Al-Abadie MS. The relationship between disease severity, disability and psychological distress in patients undergoing PUVA treatment for psoriasis. Dermatology 1994;189:234-7.
- [23]23. Kent G, Al-Abadie M. The psoriasis disability index: Further analyses. Clin Exp Dermatol 1993;18:414-6.
- [24]24. Parry EJ, Tillman DM, Long J. Audit of UVB phototherapy in the treatment of psoriasis. Br J Dermatol 1995;133:16.
- [26]26. Picardi A, Abeni D, Melchi C, Puddu P , Pasquini P . Psychiatric morbidity in dermatological outpatients: An issue to be recognized. Br J Dermatol 2000;143:983-91.
- [27]27. Hughes JE, Barraclough BM, Hamblin LG, White JE. Psychiatric symptoms in dermatology patients. Br J Psychiatry 1983;143:51-4.
- [28]28. Woodruff PW, Higgins EM, du Vivier AW, Wessely S. Psychiatric illness in patients reffered to a dermatologypsychiatry clinic. Gen Hosp Psychiatry 1997;19:29-35.
- [29]29. Stein KR, Pearce DJ, Feldman SR. The impact of biologics on the quality of life of psoriasis patients and the economics of psoriasis care. Semin Cutan Med Surg 2005;24:52-7. 233
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Vyas, J., Johns, J. R., Ali, F. M., Ingram, J. R., Salek, S., & Finlay, A. Y. (2024) · Acta Dermato Venereologica · doi:10.2340/actadv.v104.41120 · Cited by 20 · see citing works
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He, Z., Lu, C., Ou, A., Fang, J., Wang, D., Deng, J., Zhang, Z., & Yu, J. (2012) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-10-37 · Cited by 15 · see citing works
Fuat, M. S. A., Yudin, Z. M., Muhammad, J., & Zin, F. M. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph191811578 · Cited by 14 · see citing works
Vettuparambil, A., Asokan, N., & Narayanan, B. (2016) · Muller Journal of Medical Sciences and Research · doi:10.4103/0975-9727.185010 · Cited by 14 · see citing works
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Barot, P. A., Brahmbhatt, N., Ninama, H. V., Kharadi, D., & Malhotra, S. (2015) · National Journal of Medical Research · Cited by 8 · see citing works
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Rituximab Treatment and Improvement of Health-Related Quality of Life in Patients With Pemphigus
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Saki, N., Nezhad, M. M., Kasraei, H., Rezaee, M., Haghighi, N. F., & Parvizi, M. M. (2020) · Research Square · doi:10.21203/rs.3.rs-89436/v1 · Cited by 1 · see citing works
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- Authors
- Aghaei, S., Moradi, A., & Ardekani, G.
- Affiliations
- Jahrom University of Medical Sciences (IR)
- Shiraz University of Medical Sciences (IR)
- Venue
- Indian Journal of Dermatology, Venereology and Leprology
- Publisher
- Scientific Scholar
- Published
- 2009
- Volume
- 75
- Issue
- 2
- Pages
- 220
- ISSN
- 0378-6323 (ISSN-L)
- OpenAlex
- W2038973534
- Cited by
- 42
- References
- 0
- Citations by year
- 2025: 2 · 2024: 2 · 2023: 2 · 2022: 4 · 2021: 2 · 2020: 4 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 4 · 2015: 2 · 2014: 3 · 2013: 4 · 2012: 1
- FWCI
- 1.15
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Indian Journal of Dermatology Venereology and Leprology (publishedVersion)
- PubMed (publishedVersion)
- TSpace (University of Toronto) (submittedVersion)
- Bioline International (Bioline International) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Rheumatology › Spondyloarthritis Studies and Treatments
- Keywords
- psoriasis, quality of life, Psoriasis Disability Index, Persian translation, questionnaire validation, Dermatology Life Quality Index, psychological distress, plaque psoriasis, PASI, Iranian patients
- MeSH terms
- Adolescent, Adult, Female, Humans, Iran, Male, Middle Aged, Psoriasis, Quality of Life, Surveys and Questionnaires, Severity of Illness Index, Reproducibility of Results, Multilingualism, Young Adult
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