Sample size calculation
Open accessAbstract
Bioactive compounds from marine flora and fauna have extensive past and present use in the treatment of many diseases and serve as compounds of interest both in their natural form and as templates for synthetic modification. Several molecules isolated from various marine organisms (microorganisms, algae, fungi, invertebrates, and vertebrates) are currently under study at an advanced stage of clinical trials, some of them have already been marketed as drugs. This article gives an overview of current trends in screening and the activity analysis of metabolites from marine resources. Although the marine resources have been somewhat limited to date, selected bioactive from marine flora and fauna have already published. This report summarizes the screening for bioactive compounds of marine animals and marine microorganisms. Finally, new approaches for the screening of metabolites from marine resources are discussed. The goal of this article is to expose the new models and mechanisms of action of marine substances to bring new solutions for tackling some of the major public health problems.
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The sample size was calculated following the formula by Kadam and Bhalerao 2010.
“The sample size was calculated following the formula by (Kadam and Bhalerao 2010).”
From Astrocyte-specific inhibition of the primary cilium suppresses C3 expression in reactive astrocyte (2024) · cites this paper as Kadam and Bhalerao 2010
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Research works printed but not linked: 4
- [1]Kirby A Gebski V Keech AC Determining the sample size in a clinical trial Med J Aust 2002 177 256 7 12197821
- [2]Larsen S Osnes M Eidsaunet W Sandvik L Factors influencing the sample size, exemplified by studies on gastroduodenal tolerability of drugs Scand J Gastroenterol 1985 20 395 400 3875139
- [3]Prakesh B Babu SR Sureshkumar K Response of Ayurvedic therapy in the treatment of migraine without aura Int J Ayurveda Research 2010 1 29 35 PMC2876931 20532095
- [4]Cady RK Sheftell F Lipton RB O'Quinn S Jones M Putnam G Effect of early intervention with sumatriptan on migraine pain: Retrospective analyses of data from three clinical trials Clin Ther 2000 22 1035 48 11048903
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Current challenges and best-practice protocols for microbiome analysis
Bharti, R., & Grimm, D. G. (2021) · Briefings in Bioinformatics · doi:10.1093/bib/bbz155 · Cited by 592 · see citing works
Hoseini, S. G., Heshmat‐Ghahdarijani, K., Khosrawi, S., Garakyaraghi, M., Shafie, D., Roohafza, H., Mansourian, M., Azizi, E., Gheisari, Y., & Sadeghi, M. (2021) · Clinical Cardiology · doi:10.1002/clc.23682 · Cited by 22 · see citing works
Astrocyte-specific inhibition of the primary cilium suppresses C3 expression in reactive astrocyte
Muhamad, N. A., Masutani, K., Furukawa, S., Yuri, S., Toriyama, M., Matsumoto, C., Itoh, S., Shinagawa, Y., Isotani, A., Toriyama, M., et al. (2024) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-024-01482-5 · Cited by 8 · see citing works
- Authors
- Bhalerao, S., & Kadam, P.
- Affiliations
- King Edward Memorial Hospital and Seth G.S. Medical College (IN)
- Corresponding author
- Bhalerao, Supriya
- ORCID
- Bhalerao, Supriya
- Venue
- International Journal of Ayurveda Research
- Publisher
- Medknow
- Published
- 2010
- Volume
- 1
- Issue
- 1
- Pages
- 55
- ISSN
- 0974-7788 (ISSN-L)
- PMC
- PMC2876926
- OpenAlex
- W2328142025
- Cited by
- 798
- References
- 0
- Citations by year
- 2026: 60 · 2025: 73 · 2024: 88 · 2023: 82 · 2022: 84 · 2021: 80 · 2020: 79 · 2019: 64 · 2018: 51 · 2017: 38 · 2016: 27 · 2015: 14 · 2014: 21 · 2013: 12 · 2012: 7
- FWCI
- 7.82
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- cc-by
- Locations
- International Journal of Ayurveda Research (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Marine Sponges and Natural Products
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Health Sciences › Medicine › Pharmacology › Microbial Natural Products and Biosynthesis
- Keywords
- marine bioactive compounds, marine microorganisms, marine algae, marine fungi, marine invertebrates, marine vertebrates, metabolite screening, bioassay, mechanism of action, marine-derived drugs
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