Hypokalemic periodic paralysis
Open accessAbstract
Hypokalemic periodic paralysis is a rare genetic disorder characterized by recurrent attacks of skeletal muscle weakness with associated hypokalemia which is precipitated by stress, cold, carbohydrate load, infection, glucose infusion, hypothermia, metabolic alkalosis, anesthesia, and steroids. We encountered one such incidence of prolonged recovery after general anesthesia, which on further evaluation revealed a case of hypokalemic paralysis. The key to successful management of such a patient was vigilant pre-operative evaluation, perioperative monitoring, and aggressive treatment of hypokalemia when it occurs.
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Familial hypokalemic periodic paralysis (HKPP) is a rare autosomal dominant channelopathy with a defect in calcium channels resulting in muscle paralysis, but there is no hyperthyroidism in these individuals.
“This is a rare autosomal dominant channelopathy with a defect in calcium channels resulting in muscle paralysis, but there is no hyperthyroidism in these individuals [5].”
From Thyrotoxic Periodic Paralysis With Hypokalemia: A Case Study (2023) · cites this paper as [5]
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Practical aspects in the management of hypokalemic periodic paralysis
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Intravenous Treatment of Hypokalemic Periodic Paralysis
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The Recovery Profile of Hyperbaric Spinal Anesthesia With Lidocaine, Tetracaine, and Bupivacaine
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Thyrotoxic Periodic Paralysis With Hypokalemia: A Case Study
Mebane, N. B., Khan, A., Bevinal, M., & Davis, E. (2023) · Cureus · doi:10.7759/cureus.40757 · Cited by 3 · see citing works
- Authors
- Abbas, H., Kothari, N., & Bogra, J.
- Affiliations
- King George's Medical University (IN)
- Corresponding author
- Abbas, Haider
- ORCID
- Kothari, Nikhil
- Venue
- National Journal of Maxillofacial Surgery
- Published
- 2012-07
- Volume
- 3
- Issue
- 2
- Pages
- 220-221
- ISSN
- 0975-5950 (ISSN-L)
- 2229-3418
- PMC
- PMC3700163
- OpenAlex
- W1970717908
- Cited by
- 26
- References
- 11
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 3 · 2022: 1 · 2021: 4 · 2020: 2 · 2019: 3 · 2018: 2 · 2017: 1 · 2016: 2 · 2014: 1
- FWCI
- 0.26
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- cc-by-nc-sa
- Locations
- National Journal of Maxillofacial Surgery (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Potassium and Related Disorders
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Sedative Agents
- Health Sciences › Medicine › Surgery › Muscle and Compartmental Disorders
- Keywords
- hypokalemic periodic paralysis, hypokalemia, skeletal muscle weakness, general anesthesia, perioperative monitoring, preoperative assessment, metabolic alkalosis, genetic disorders
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