Abnormal brain activity in adolescents with Internet addiction who attempt suicide: an assessment using functional magnetic resonance imaging
Open accessAbstract
Internet addiction is associated with an increased risk of suicidal behavior and can lead to brain dysfunction among adolescents. However, whether brain dysfunction occurs in adolescents with Internet addiction who attempt suicide remains unknown. This observational cross-sectional study enrolled 41 young Internet addicts, aged from 15 to 20 years, from the Department of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, China from January to May 2018. The participants included 21 individuals who attempted suicide and 20 individuals with Internet addiction without a suicidal attempt history. Brain images in the resting state were obtained by a 3.0 T magnetic resonance imaging scanner. The results showed that activity in the gyrus frontalis inferior of the right pars triangularis and the right pars opercularis was significantly increased in the suicidal attempt group compared with the non-suicidal attempt group. In the resting state, the prefrontal lobe of adolescents who had attempted suicide because of Internet addiction exhibited functional abnormalities, which may provide a new basis for studying suicide pathogenesis in Internet addicts. The study was authorized by the Ethics Committee of Chongqing Medical University, China (approval No. 2017 Scientific Research Ethics (2017-157)) on December 11, 2017.
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In adolescents with internet addiction, resting-state prefrontal cortex activity was increased in recent suicide attempters compared to non-attempters.
“Moreover, a study of adolescents with internet addiction found that resting-state prefrontal cortex activity was increased in recent suicide attempters compared to non-attempters (78).”
From New methods for assessing rapid changes in suicide risk (2021) · cites this paper as [78]
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New methods for assessing rapid changes in suicide risk
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BackgroundMethod
- Authors
- Huang, Y., Xu, L., Kuang, L., Wang, W., Cao, J., & Xiao, M.-N.
- Affiliations
- Chongqing Medical and Pharmaceutical College (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
- Department of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China
- Corresponding author
- Xu, Lu
- Kuang, Li
- Venue
- Neural Regeneration Research
- Published
- 2020-01-28
- Volume
- 15
- Issue
- 8
- Pages
- 1554-1559
- ISSN
- 1673-5374 (ISSN-L)
- 1876-7958
- PMC
- PMC7059585
- OpenAlex
- W3003433933
- Cited by
- 22
- References
- 31
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 2 · 2023: 1 · 2022: 4 · 2021: 7 · 2020: 2
- FWCI
- 1.40
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Neural Regeneration Research (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Social Sciences › Sociology and Political Science › Impact of Technology on Adolescents
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Keywords
- internet addiction, suicide attempts, adolescents, resting-state brain activity, prefrontal cortex, pars triangularis, pars opercularis, brain dysfunction
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