The magic of magic bugs in oral cavity: probiotics
Open accessAbstract
The aim of this review is to present an update about the current status of probiotics in the field of dentistry. Oral infections are the most common forms of infections. It is necessary to understand the role of the ecology and microbiology of the oral cavity in better understanding of the pathogenesis of various oral diseases. The concept of bacteriotherapy has been an emerging field in dentistry. The use of health-beneficial micro-organisms to heal diseases or support immune function was first introduced in the beginning of the 20(th) century. Probiotics are dietary supplements containing potentially beneficial bacteria or yeasts and it has been found to be beneficial to the host health. In medicine, probiotics are used mainly in support therapy for gastro-intestinal diseases. In recent years, probiotics have been used as a treatment to promote oral health. This approach has shown promising results in the oral cavity with respect to control of chronic diseases such as dental caries, periodontitis, and recurring problems such as halitosis and candidal infections. Despite the immense potential of probiotics, data are still deficient on the probiotic action in the oral cavity, which further mandates randomized trials before any concrete clinical recommendations can be arrived.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Probiotic therapy exerts a beneficial effect on dental caries, periodontitis, and pharyngitis in the oral cavity, as well as on obesity, hypertension, insulin resistance, and heart failure via the gut.
“Given, however, that probiotic therapy exerts a beneficial effect on dental caries, periodontitis, and pharyngitis in the oral cavity[408–411], as well as on obesity, hypertension, insulin resistance, and heart failure via the gut(reviewed:[399,403])”
From Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health (2017) · cites this paper as [411]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Dietary Modulation of the Human Colonic Microbiota: Introducing the Concept of Prebiotics
Gibson, G. R., & Roberfroid, M. B. (1995) · Journal of Nutrition · doi:10.1093/jn/125.6.1401 · Cited by 7,659 · see citing works
AFRC, R. F. (1989) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1989.tb05105.x · Cited by 4,831 · see citing works
Probiotics in man and animals.
Fuller, R. (1989) · PubMed · Cited by 1,292 · see citing works
Potential Uses of Probiotics in Clinical Practice
Reid, G., Jaß, J., Sebulsky, M. T., & McCormick, J. K. (2003) · Clinical Microbiology Reviews · doi:10.1128/cmr.16.4.658-672.2003 · Cited by 918 · see citing works
Salminen, M. K., Tynkkynen, S., Rautelin, H., Saxelin, M., Vaara, M., Ruutu, P., Sarna, S., Valtonen, V., & Järvinen, A. (2002) · Clinical Infectious Diseases · doi:10.1086/342912 · Cited by 419 · see citing works
Short-term consumption of probiotic-containing cheese and its effect on dental caries risk factors
Ahola, A. J., Yli‐Knuuttila, H., Suomalainen, T., Poussa, T. A., Ahlström, A., Meurman, J. H., & Korpela, R. (2002) · Archives of Oral Biology · doi:10.1016/s0003-9969(02)00112-7 · Cited by 387 · see citing works
Decreased gum bleeding and reduced gingivitis by the probiotic Lactobacillus reuteri.
Krasse, P., Carlsson, B., Dahl, C., Paulsson, A., Nilsson, Å. L., & Sinkiewicz, G. (2006) · PubMed · Cited by 358 · see citing works
Probiotics: do they have a role in oral medicine and dentistry?
Meurman, J. H. (2005) · European Journal Of Oral Sciences · doi:10.1111/j.1600-0722.2005.00191.x · Cited by 348 · see citing works
Probiotics: contributions to oral health
Meurman, J. H., & Stamatova, I. (2007) · Oral Diseases · doi:10.1111/j.1601-0825.2007.01386.x · Cited by 337 · see citing works
Senok, A. C., Ismaeel, A. Y., & Botta, G. A. (2005) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2005.01228.x · Cited by 329 · see citing works
Kõll-Klais, P., Mändar, R., Leibur, E., Marcotte, H., Hammarström, L. L. G., & Mikelsaar, M. (2005) · Oral Microbiology and Immunology · doi:10.1111/j.1399-302x.2005.00239.x · Cited by 328 · see citing works
Probiotics Reduce the Prevalence of Oral Candida in the Elderly—a Randomized Controlled Trial
Hatakka, K., Ahola, A. J., Yli‐Knuuttila, H., Richardson, M. D., Poussa, T. A., Meurman, J. H., & Korpela, R. (2007) · Journal of Dental Research · doi:10.1177/154405910708600204 · Cited by 306 · see citing works
Probiotics, prebiotics and antioxidants as functional foods.
Grajek, W., Olejnik, A. M., & Sip, A. (2005) · Acta Biochimica Polonica · doi:10.18388/abp.2005_3428 · Cited by 280 · see citing works
Bacteriotherapy and probiotics’ role on oral health
Çağlar, E., Kargül, B., & Tanboğa, İ. H. (2005) · Oral Diseases · doi:10.1111/j.1601-0825.2005.01109.x · Cited by 249 · see citing works
Probiotics: their role in the treatment and prevention of disease
Doron, S., & Gorbach, S. L. (2006) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.4.2.261 · Cited by 192 · see citing works
Probiotics and Their Potential Health Claims
Santosa, S., Farnworth, E. R., & Jones, P. J. H. (2006) · Nutrition Reviews · doi:10.1111/j.1753-4887.2006.tb00209.x · Cited by 184 · see citing works
Regulatory T cells in inflammatory bowel disease
Boden, E. K., & Snapper, S. B. (2008) · Current Opinion in Gastroenterology · doi:10.1097/mog.0b013e328311f26e · Cited by 142 · see citing works
Montalto, M., Vastola, M. E., Marigo, L., Covino, M., Graziosetto, R., Curigliano, V., Santoro, L., Cuoco, L., Manna, R., & Gasbarrini, A. (2004) · Digestion · doi:10.1159/000076559 · Cited by 141 · see citing works
Effect of Weissella cibaria Isolates on the Formation of Streptococcus mutans Biofilm
Kang, M., Chung, J. H., Kim, S.-R., Yang, K.-H., & Oh, J. (2006) · Caries Research · doi:10.1159/000094288 · Cited by 118 · see citing works
Meurman, J. H., Antila, H., Korhonen, A., & Salminen, S. (1995) · European Journal Of Oral Sciences · doi:10.1111/j.1600-0722.1995.tb00169.x · Cited by 112 · see citing works
[Use of probiotics Bifidumbacterin and Acilact in tablets in therapy of periodontal inflammations].
Grudianov, A. I., Dmitrieva, N. A., & Фоменко, Е. В. (2002) · PubMed · Cited by 73 · see citing works
A probiotic approach to caries management.
Anderson, M. H., & Shi, W. (2006) · PubMed · Cited by 69 · see citing works
Potential of probiotics as biotherapeutic agents targeting the innate immune system
Oyetayo, V. O., & Oyetayo, F. L. (2005) · AFRICAN JOURNAL OF BIOTECHNOLOGY · doi:10.4314/ajb.v4i2.15065 · Cited by 61 · see citing works
Bacteriotherapy: the time has come
Huovinen, P. (2001) · BMJ · doi:10.1136/bmj.323.7309.353 · Cited by 54 · see citing works
Volozhin, A. I., Vk, I., Maksimovskiĭ, I. M., et al. (2004) · PubMed · Cited by 32 · see citing works
Role of Probiotics in Dental Caries and Periodontal Disease
Bhardwaj, A., & Bhardwaj, S. V. (2012) · Archives of Clinical and Experimental Surgery (ACES) · doi:10.5455/aces.20120212100645 · Cited by 14 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- [1]Anthony R Molecular Oral Microbiology 2008 Norfolk, UK Caister Academic Press
Cited by
Sorted by citations
Koch, C. D., Gladwin, M. T., Freeman, B. A., Lundberg, J. O., Weitzberg, E., & Morris, A. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.12.015 · Cited by 186 · see citing works
- Authors
- Umar, D., Anusha, R., Basheer, B., & Baroudi, K.
- Affiliations
- Al-Farabi College (SA)
- Corresponding author
- Umar, Dilshad
- Venue
- Journal of Advanced Pharmaceutical Technology amp Research
- Published
- 2015
- Volume
- 6
- Issue
- 2
- Pages
- 43
- ISSN
- 0976-2094 (ISSN-L)
- 2231-4040
- PMC
- PMC4397617
- OpenAlex
- W2030260712
- Cited by
- 51
- References
- 26
- Citations by year
- 2025: 2 · 2024: 7 · 2023: 6 · 2022: 3 · 2021: 2 · 2020: 7 · 2019: 5 · 2018: 7 · 2017: 4 · 2016: 6 · 2015: 2
- FWCI
- 8.56
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc-sa
- Locations
- Journal of Advanced Pharmaceutical Technology amp Research (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Dentistry › Periodontics › Dental Health and Care Utilization
- Keywords
- probiotics, oral microbiota, oral health, bacterial therapy, dental caries, periodontitis, halitosis, candidiasis, oral infection, probiotic therapy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
