Statistical errors in scientific research: A narrative review
Open accessAbstract
Statistics is the backbone of scientific research. Statistical errors are an inevitable part of any study. A researcher needs to be aware of various types of statistical errors, their implications, and steps to minimize them. Essentially, statistical errors may creep into medical literature either by deriving false-positive or false-negative interpretations during analysis or through fallacies in data collection. Manipulation of statistical errors to derive one’s preferred conclusions from a study is unethical. We searched medical literature in databases such as PubMed, Embase, and Cochrane for the articles published between July 2014 and June 2023 followed by abstract screening which led to the study of 8 full-length articles to gather the pertinent material. This review highlights many of the common statistical errors along with examples and suggested corrective actions.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In meta-analyses, additional errors surface, such as inappropriate model selection, biased study selection, dependency, and ignoring incomplete data in selected studies.
“In meta-analyses, additional errors surface, such as inappropriate model selection, biased study selection, dependency, and ignoring incomplete data in selected studies.”
From Artificial Intelligence in Detecting Statistical Errors: Implications for Authors, Reviewers, and Editors (2025) · cites this paper as [4]
Common statistical errors in published research include inappropriate use of the t-test and Pearson's bivariate correlation, errors in logistic and linear regression analyses, incorrect reporting of P values solely, and incorrect reporting of medians and means and interquartile ranges.
“Common statistical errors in published research include the inappropriate use of the t-test and Pearson’s bivariate correlation, errors in logistic and linear regression analyses, the incorrect reporting of P values solely, and the incorrect reporting of medians and means and interquartile ranges.”
From Artificial Intelligence in Detecting Statistical Errors: Implications for Authors, Reviewers, and Editors (2025) · cites this paper as [4]
Cites
Statistics: P values are just the tip of the iceberg
Leek, J. T., & Peng, R. D. (2015) · Nature · doi:10.1038/520612a · Cited by 211 · see citing works
Type I, II, and III statistical errors: A brief overview
Stoltzfus, J. C., & Kaur, P. (2017) · International Journal of Academic Medicine · doi:10.4103/ijam.ijam_92_17 · Cited by 22 · see citing works
Statistical Errors in Clinical Studies
Slutsky, D. J. (2013) · Journal of Wrist Surgery · doi:10.1055/s-0033-1359421 · Cited by 20 · see citing works
Common Statistical Errors in Scientific Investigations: A Simple Guide to Avoid Unfounded Decisions
Rovetta, A. (2023) · Cureus · doi:10.7759/cureus.33351 · Cited by 12 · see citing works
Ten Common Statistical Errors from All Phases of Research, and Their Fixes
Borg, D. N., Lohse, K. R., & Sainani, K. L. (2020) · PM&R · doi:10.1002/pmrj.12395 · Cited by 10 · see citing works
To “P” or not to “P”, that is the question: A narrative review on P value
Darling, H. (2021) · Cancer Research Statistics and Treatment · doi:10.4103/crst.crst_222_21 · Cited by 7 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Alnaimat, F., AlSamhori, A. R. F., El Sharu, H., Othman, L., Oralbek, A., & Zimba, O. (2025) · Journal of Korean Medical Science · doi:10.3346/jkms.2025.40.e342 · Cited by 4 · see citing works
Common wrong beliefs about statistical testing: recent trends in biomedical sciences
Rovetta, A., & Mansournia, M. A. (2025) · Current Opinion in Epidemiology and Public Health · doi:10.1097/pxh.0000000000000054 · Cited by 3 · see citing works
An Extended UTAUT Model to Explain Factors Influencing Smart City Technology Adoption
Al-Haraizah, A., Jawarneh, M. M. M., Kumar, R., Khrisat, D. A., & Mrayat, O. I. A. (2025) · Human Behavior and Emerging Technologies · doi:10.1155/hbe2/3799390 · Cited by 4 · see citing works
BioMedStatX – Statistical workflows for reliable biomedical data analysis
Krumm, P., Böttcher, N., Ottermanns, R., Pufe, T., & Fragoulis, A. (2025) · MethodsX · doi:10.1016/j.mex.2025.103776 · Cited by 2 · see citing works
Methods for Estimating Sample Size in Structural Equation Modeling
Almeida, F. L. (2026) · Journal of Learning Theory and Methodology · doi:10.17309/jltm.2026.7.2.03 · Cited by 1 · see citing works
BioMedStatX – Statistical Workflows for Reliable Biomedical Data AnalysisPreprint
Krumm, P., Böttcher, N., Ottermanns, R., Pufe, T., & Fragoulis, A. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5407324
Léonard, F., & Tirelli, E. (2026) · Journal of Trial and Error · doi:10.36850/34b0-42b1 · Cited by 1 · see citing works
Between numbers and biases: challenges in data analysis in scientific research
Higino, T. M. M., dos Santos, M. H. A., Cunha, M. J. B., & Soares, A. K. D. A. (2026) · Cuadernos de Educación y Desarrollo · doi:10.55905/cuadv18n8-005
- Authors
- Darling, H.
- Affiliations
- Department of Medicine, 5 Air Force Hospital, Jorhat, Assam, India
- Corresponding author
- Darling, HS
- ORCID
- Darling, HS
- Venue
- Cancer Research, Statistics, and Treatment
- Published
- 2024-04
- Volume
- 7
- Issue
- 2
- Pages
- 241-249
- ISSN
- 2590-3225 (ISSN-L)
- 2590-3233
- OpenAlex
- W4400005881
- Cited by
- 8
- References
- 6
- Citations by year
- 2026: 3 · 2025: 5
- FWCI
- 0.53
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc-sa
- Locations
- Cancer Research Statistics and Treatment (publishedVersion, cc-by-nc-sa)
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Epidemiology
- Physical Sciences › Mathematics › Statistics and Probability › Statistics Education and Methodologies
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Keywords
- statistical errors, research misconduct, false positives, false-negative results, data collection errors, statistical fallacies, research ethics, medical literature
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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