Synthetic and natural iron chelators: Therapeutic potential and clinical use
Hatcher, Heather C, Singh, Ravi N, Torti, Frank M, Torti, Suzy V·2009·Future Medicinal Chemistry
Cites (250)
Items 201–250 of 250
- Guidelines on iron chelation therapy in patients with myelodysplastic syndromes and transfusional iron overloadNorbert Gattermann · 2007 · Leukemia Research
- Role of zinc and iron chelation in apoptosis mediated by tachpyridine, an anti-cancer iron chelatorRong Zhao, Roy P. Planalp, Rong Ma, Bryan T. Greene, Bradley Todd Jones, Martin W. Brechbiel, Frank M. Torti, Suzy V. Torti · 2004 · Biochemical Pharmacology
- The flavonoid quercetin induces hypoxia-inducible factor-1α (HIF-1α) and inhibits cell proliferation by depleting intracellular ironAnastasia Triantafyllou, Panagiotis Liakos, Andreas K. Tsakalof, Georgia Chachami, Efrosyni Paraskeva, Pashalis-Adam Molyvdas, Elena Georgatsou, George Simos, Sophia Bonanou · 2006 · Free Radical Research
- Zinc supplementation decreases the development of atherosclerosis in rabbitsMinqin Ren, Reshmi Rajendran, Pan Ning, Benny Tan Kwong Huat, Ong Choon Nam, F. Watt, Andrew M. Jenner, Barry B. Halliwell · 2006 · Free Radical Biology and Medicine
- Iron Involvement in Multiple Signaling Pathways of Atherosclerosis: A Revisited HypothesisXi Yuan, Wei Li · 2008 · Current Medicinal Chemistry
- The Metabolites of the Cardioprotective Drug Dexrazoxane Do Not Protect Myocytes from Doxorubicin-Induced CytotoxicityBrian B. Hasinoff, Patricia E. Schroeder, Daywin Patel · 2003 · Molecular Pharmacology
- Glucose metabolism disorders improvement in patients with thalassaemia major after 24-36 months of intensive chelation therapy.Odysseas Platis, Georgios K. Anagnostopoulos, Kallisteni Farmaki, Markos Posantzis, Efstathios D. Gotsis, Georgios Tolis · 2004 · PubMed
- Triapine and cytarabine is an active combination in patients with acute leukemia or myelodysplastic syndromeKaren W L Yee, Jörge E. Cortes, Alessandra Ferrajoli, Guillermo Garcia‐Manero, Srđan Verstovšek, William G. Wierda, Deborah Ann Thomas, Stefan H Faderl, Ivan King, Susan Mary O'Brien et al. · 2006 · Leukemia Research
- Transfusion and Exchange Transfusion in Sickle Cell Anaemias, with Particular Reference to Iron MetabolismJohn B. Porter, E. R. Huehns · 2009 · Acta Haematologica
- Coronary Microvascular Adaptation to Myocardial Metabolic Demand Can Be Restored by Inhibition of Iron-Catalyzed Formation of Oxygen Free Radicals in Type 2 Diabetic PatientsAlain Nitenberg, Séverine Ledoux, Paul Elie Valensi, R. N. Sachs, Isabelle Antony · 2002 · Diabetes
- Iron indexes and total antioxidant status in response to soy protein intake in perimenopausal women,,,James H. Swain, D. Lee Alekel, Sarah B. Dent, Charles T. Peterson, Manju B. Reddy · 2002 · American Journal of Clinical Nutrition
- Effects of red grape skin and seed extract supplementation on atherosclerosis in Watanabe heritable hyperlipidemic rabbitsHanne Winther Frederiksen, Alicja Mortensen, Malene Schrøder, Henrik Lauritz Frandsen, Anette Bysted, Pia Knuthsen, Salka Elbøl Rasmussen · 2007 · Molecular Nutrition & Food Research
- Desferrioxamine Inhibits Production of Cytotoxic Heme to Protein Cross-Linked Myoglobin: A Mechanism to Protect against Oxidative Stress without Iron ChelationBrandon J. Reeder, Michael T. Wilson · 2005 · Chemical Research in Toxicology
- A novel protein–mineral interfaceDmitry G. Alexeev, Haizhong Zhu, Maolin Guo, Weiqing Zhong, Dominic J. B. Hunter, Weiping Yang, Dominic J. Campopiano, Peter John Sadler · 2003 · Nature Structural & Molecular Biology
- Physicochemical study of floranol, its copper(II) and iron(III) complexes, and their inhibitory effect on LDL oxidationFrançoise Vasconcelos Botelho, Jacqueline Isaura Alvarez-Leite, Virginia Soares Lemos, Adriano M.C. Pimenta, Hállen D. R. Calado, Túlio Matencio, C.T. Miranda, Elene Cristina Pereira-Maia · 2007 · Journal of Inorganic Biochemistry
- Study of daunorubicin cardiotoxicity prevention with pyridoxal isonicotinoyl hydrazone in rabbitsTomáš Šimůnek, Ivona Klimtová, J. Kaplanová, Martin Štěrba, Y Mazurová, Michaela Adamcová, Radomír Hrdina, Vladimír Geršl, Přemysl Poňka · 2004 · Pharmacological Research
- Analyses for binding of the transferrin family of proteins to the transferrin receptor 2Hiroshi Kawabata, Xiangjun Tong, Takafumi Kawanami, Yuji Wano, Yuko Hirose, Susumu Sugai, Harold Phillip Koeffler · 2004 · British Journal of Haematology
- Oxo-iron clusters in a bacterial iron-trafficking protein: new roles for a conserved motifHaizhong Zhu, Dmitry G. Alexeev, Dominic J. B. Hunter, Dominic J. Campopiano, Peter John Sadler · 2003 · Biochemical Journal
- Prolonged Exposure to LPS Increases Iron, Heme, and p22 phox Levels and NADPH Oxidase Activity in Human Aortic Endothelial CellsLixin Li, Balz B. Frei · 2009 · Arteriosclerosis Thrombosis and Vascular Biology
- Soy Protein Influences the Development of the Metabolic Syndrome in Male Obese ZDFxSHHF RatsJeremy E. Davis, Muhammad Javed Iqbal, Jena J. Steinle, J. Oitker, D. Allan Higginbotham, Richard G. Peterson, William J. Banz · 2005 · Hormone and Metabolic Research
- Therapeutic Potential of Iron Chelators in Cancer TherapyRichardson, Des R. · 2002 · Advances in Experimental Medicine and Biology
- Cell Permeable Iron Chelators as Potential Cancer Chemotherapeutic AgentsPahl, Paula M. B., Horwitz, Lawrence D. · 2005 · Cancer Investigation
- Iron chelation, quo vadis?Hanspeter Nick · 2007 · Current Opinion in Chemical Biology
- Soy protein isoflavones, lipids and arterial diseaseMara Z. Vitolins, Mary S. Anthony, Gregory L. Burke · 2001 · Current Opinion in Lipidology
- In vitro and In vivo Radiosensitization Induced by the Ribonucleotide Reductase Inhibitor Triapine (3-Aminopyridine-2-Carboxaldehyde-Thiosemicarbazone)Christopher Andrew Barker, William E. Burgan, Donna J. Carter, David Cerna, David R. Gius, Melinda G. Hollingshead, Kevin A. Camphausen, Philip J. Tofilon · 2006 · Clinical Cancer Research
- Dexrazoxane (ICRF-187) Protects Cardiac Myocytes Against Hypoxia-Reoxygenation DamageBrian B. Hasinoff · 2002 · Cardiovascular Toxicology
- Evaluation of New Iron Chelators for Clinical UseJohn B. Porter · 2009 · Acta Haematologica
- Desferrithiocin is a more potent antineoplastic agent than desferrioxamineAnthony Kicic, Anita C. G. Chua, Erica Baker · 2002 · British Journal of Pharmacology
- PCR differential display-based identification of regulator of G protein signaling 10 as the target gene in human colon cancer cells induced by black tea polyphenol theaflavin monogallateJiebo Lu, Alexander Gosslau, Alice Y.‐C. Liu, Kuang Yu Chen · 2008 · European Journal of Pharmacology
- Efficacy of Curcuminoids in Alleviation of Iron Overload and Lipid Peroxidation in Thalassemic MiceThephinlap, C., Phisalaphong, C., Fucharoen, S., Porter, J., Srichairatanakool, S. · 2009 · Medicinal Chemistry
- Evolution of OGTT in patients with β-thalassaemia major in relation to chelation therapyAthanasios Christoforidis, Vassilios Perifanis, Ioanna Tsatra, Efthymia Vlachaki, Miranda Athanassiou‐Metaxa · 2006 · Diabetes Research and Clinical Practice
- Chelator-facilitated removal of iron from transferrin: relevance to combined chelation therapyDevanur Ld, Robert W. Evans, Patricia Evans, Robert C. Hider · 2007 · Biochemical Journal
- Synthesis and Potent Antitumor Activities of Novel 1,3,5-cis,cis-Triaminocyclohexane N-Pyridyl DerivativesHyun‐Soon Chong, Suzy V. Torti, Rong Ma, Frank M. Torti, Martin W. Brechbiel · 2004 · Journal of Medicinal Chemistry
- Optimal Management Strategies for Chronic Iron OverloadJames C. Barton · 2007 · Drugs
- Short Oxo–Titanium( IV ) Bond in Bacterial Transferrin: A Protein Target for MetalloantibioticsMaolin Guo, Ian Harvey, Dominic J. Campopiano, Peter John Sadler · 2006 · Angewandte Chemie International Edition
- Oral Iron ChelatorsJanet L. Kwiatkowski · 2008 · Pediatric Clinics of North America
- Black tea polyphenols restrict benzopyrene-induced mouse lung cancer progression through inhibition of Cox-2 and induction of caspase-3 expression.Sarmistha Banerjee, Sugata Manna, Sudeshna Mukherjee, Debalina Pal, Chinmay Kr. Panda, Sukta Das · 2006 · PubMed
- Soy Protein Influences Insulin Sensitivity and Cardiovascular Risk in Male Lean SHHF RatsJeremy E. Davis, Jena J. Steinle, D. Allan Higginbotham, J. Oitker, Richard G. Peterson, William J. Banz · 2005 · Hormone and Metabolic Research
- Theaflavin Ameliorates Cerebral Ischemia-Reperfusion Injury in Rats Through Its Anti-Inflammatory Effect and Modulation of STAT-1Fei Cai, Cairong Li, Jiliang Wu, Jianguo Chen, Chao Liu, Qing Min, Wei Yu, Changhan Ouyang, Jinhe Chen · 2006 · Mediators of Inflammation
- Examination of the potential long-lasting protective effect of ICRF-187 against anthracycline-induced chronic cardiomyopathyEugene H. Herman, Victor J. Ferrans · 1990 · Cancer Treatment Reviews
- Iron Chelation and Vascular Function: In Search of the MechanismsFerrara, Dardo E., Taylor, W. Robert · 2005 · Arteriosclerosis, Thrombosis, and Vascular Biology
- Cranberry Phenolics: Effects on Oxidative Processes, Neuron Cell Death, and Tumor Cell GrowthCatherine Camaioni Neto, Marva I. Sweeney, Toni L. Lamoureaux, Frankie Solomon, Miwako Kondo, Shawna L. MacKinnon · 2005 · ACS symposium series
- Free radicals, myocytes and reperfusion injuryJeremy J. O. Turner, Catherine A Rice-Evans, Michael J. Davies, Emma Newman · 1990 · Biochemical Society Transactions
- Combined chelation therapy improves glucose metabolism in patients with β‐thalassaemia majorAthanasios Christoforidis, Vassilios Perifanis, Miranda Athanassiou‐Metaxa · 2006 · British Journal of Haematology
- The desferrithiocin (DFT) class of iron chelators: potential as antineoplastic agents.Anthony Kicic, Anita C. G. Chua, Erica Baker · 2002 · PubMed
- Competing pathways of iron chelation: Angiogenesis or anti‐tumor activity: Targeting different molecules to induce specific effectsNghia T.V. Le, Des Raymond Richardson · 2004 · International Journal of Cancer
- Modulation of cell proliferation and polyamine metabolism in rat liver cell cultures by the iron chelator O-trensoxFrançois Gaboriau, Cindy Laupen-Chassay, Nicole Pasdeloup, Jean‐Louis Pierre, Pierre Brissot, Gérard Lescoat · 2006 · BioMetals
- Iron chelator differentially activates macrophage inflammatory protein-3α/CCL20 in immortalized and malignant human oral keratinocytesSun‐Kyung Lee, Jun Lee, Seung‐Ki Min, Dal-Ho Won, You-Mee Lee, Hyun‐Dae Lim, Wan Lee, Hyun‐Ock Pae, Hun‐Taeg Chung, Chang‐Duk Jun et al. · 2008 · Archives of Oral Biology
- Oral iron chelation therapy with deferiprone in patients with Thalassemia Major.Muhammad Raihan Sajid, Farooq Ghani, Salman Naseem Adil, Mohammad Khurshid · 2009 · PubMed
- Influence of ligand structure on Fe(II) spin-state and redox rate in cytotoxic tripodal chelatorsMatt L. Childers, Joonhyung Cho, Celeste A.S. Regino, Martin W. Brechbiel, Antonio G. DiPasquale, Arnold L. Rheingold, Suzy V. Torti, Frank M. Torti, Roy P. Planalp · 2007 · Journal of Inorganic Biochemistry