Effects of d-chiro-inositol in lean women with the polycystic ovary syndrome

Iuorno, Maria J., Jakubowicz, Daniela J., Baillargeon, Jean-Patrice, Dillon, Pamela, Gunn, Ronald D., Allan, Geoffrey, Nestler, John E.·2002·Endocrine Practice

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  17. Inositol treatment of anovulation in women with polycystic ovary syndrome: a meta-analysis of randomised trials
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  18. Comparative efficacy of combined myo-inositol and D-chiro inositol versus metformin across PCOS Phenotypes: enhancing ovarian function, ovulation, and stress response in a prospective clinical trial
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  20. Dietary Approaches and Alternative Therapies for Polycystic Ovary Syndrome
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  49. Systematic analysis of the pharmacology of myoinositol and D-chiroinositola
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  50. A prospective randomised controlled study on the effects of myoinositol on ovarian functions and metabolic factors in women with polycystic ovarian syndrome
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  54. Advisory Board Italiano sulla sindrome dell'ovaio policistico (PCOS): dalle osservazioni all'esperienze cliniche sull'uso del mioinositolo (MYO) e dell'acido alfa-lipoico (ALA) per migliorare i quadri della sindrome
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  55. Fagopyrum esculentum
    T. K. Lim · 2012 · Springer eBooks
  56. Effects of Inositol in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis of Randomized Controlled Trials
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  59. Evidence-based pharmacology of myoinositol
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  60. Medical Management of Polycystic Ovary Syndrome
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  61. Does the combination of myo-inositol improve pregnancy outcomes in obese polycystic ovary syndrome women undergoing ovarian stimulation with clomiphene citrate?
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  62. Polycystic Ovary Syndrome: Pathophysiology, Presentation and Treatment a Mini-Review Article
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  63. Abnormal blood pressure and hyperandrogenemia in first degree relatives of women with polycystic ovarian syndrome referring to gynecology clinics of Shiraz Medical University.
    Marzieh Akbarzadeh, Fatah Moradi, Dabbaghmanesh MH, Najaf Zare, Parsanezhed Me · 2014
  64. Polycystic Ovarian Syndrome
    Melinda R. Ring · 2012 · Elsevier eBooks
  65. Use of myo-inositol in the treatment of PCOS symptoms in adolescents
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  66. Supplementation with d-chiro-inositol in women
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  67. Role of inositol and its isomers in glucose metabolism
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  68. Inositols and other supplements in the management of PCOS
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  69. Use of Diet and Myoinositol in Postmenopausal Women: A New Approach to the Metabolic Syndrome
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  70. Inositolo e sindrome dell'ovaio micropolicistico
    Enrico Papaleo, M Molgora, Elena Marsiglio, Francesco Fusi, Claudio Brigante, Lavinia Quaranta, Augusto G. Ferrari · 2009 · CNR Solar (Scientific Open-access Literature Archive and Repository) (Consiglio Nazionale delle Ricerche)
  71. QUALITÀ OVOCITARIA IN DONNE CON PCOS TRATTATE MEDIANTE INOSITOLO
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  72. Pinitol and D-chiro-Inositol
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  73. Evaluation of ovarian function and metabolic factors in women affected by polycystic ovary syndrome after treatment with
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  74. Polycystic Ovarian Syndrome
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  75. REPRODUCTIVE HEALTH AND CARDIOMETABOLIC RISK
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  76. Polycystic ovary syndrome: a vitamin deficiency? Floating a new pathogenesis hypothesis.
    Vittorio Unfer · 2010 · PubMed
  77. 日本文化と日本人--地域性,県民性と変化の問題
    孝男 祖父江 · 1994 · 学術月報
  78. PCOS and Assisted Reproduction Technique: Role and Relevance of Inositols
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  79. Inositols
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  80. Introduction to the history of inositols: A tale of scientists
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  81. Overcoming inositol resistance
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  82. Nutritional support of oocyteogenesis, ovulatory menstrual cycles with folate cycle vitamins (vitamins B1, B6, B12, active form B9) and vitamin B8 vitamers (Myo- and D-chiroinositol in a ratio of 40:1) during pre-conception preparation
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  83. Efficacy of pretreatment D-chiro-inositol and cyproterone acetate-ethinyl estradiol combination therapy compared to cyproterone acetate-ethinyl estradiol alone for ovarian response in polycystic ovary syndrome with high AMH
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  84. Additional file 1 of Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials
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  85. Study of the insulin-sensitizing effect of myo-inositol in mouse : Evaluation of the nutritional interest of a myo-inositol supplementation
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  86. Metabolic Phenotype Predicts Biochemical Response to Inositol Supplementation in Polycystic Ovary Syndrome: A Systematic Review and Meta‐Analysis
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  87. D-ХИРО-ИНОЗИТОЛ: ОБЗОР КЛИНИЧЕСКИХ ПРЕИМУЩЕСТВ ПРИ ЭСТРОГЕНЗАВИСИМЫХ НАРУШЕНИЯХ У МУЖЧИН
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