VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD

Tresse, Emilie, Salomons, Florian A., Vesa, Jouni, Bott, Laura C., Kimonis, Virginia, Yao, Tso-Pang, Dantuma, Nico P., Taylor, J. Paul·2010·Autophagy
DOI 10.4161/auto.6.2.11014

Cited by (438)

Items 201–300 of 438

  1. Paget’s disease: a review of the epidemiology, etiology, genetics, and treatment
    Babajan Banaganapalli, Ibrahim Fallatah, Fai Alsubhi, Preetha J. Shetty, Zuhier Ahmed Awan, Ramu Elango, Noor Ahmad Shaik · 2023 · Frontiers in Genetics
  2. p97-Containing Complexes in Proliferation Control and Cancer: Emerging Culprits or Guilt by Association?
    Dale S. Haines · 2010 · Genes & Cancer
  3. Mechanisms of neuronal survival safeguarded by endocytosis and autophagy
    Melina Overhoff, Elodie De Bruyckere, Natalia L. Kononenko · 2020 · Journal of Neurochemistry
  4. Protein Interaction Profiling of the p97 Adaptor UBXD1 Points to a Role for the Complex in Modulating ERGIC-53 Trafficking
    Dale S. Haines, J. Eugene Lee, Stephen L. Beauparlant, Dane B. Kyle, Willem den Besten, Michael J. Sweredoski, Robert L.J. Graham, Sonja Y. Hess, Raymond J. Deshaies · 2012 · Molecular & Cellular Proteomics
  5. Mutation-dependent aggregation and toxicity in a Drosophila model for UBQLN2-associated ALS
    Sang Hwa Kim, Shannon Stiles, Joseph Feichtmeier, Nandini Ramesh, Lihong Zhan, Mark Scalf, Lloyd M. Smith, Udai Bhan Pandey, Randal S. Tibbetts · 2017 · Human Molecular Genetics
  6. VCP/p97 UFMylation stabilizes BECN1 and facilitates the initiation of autophagy
    Zhifeng Wang, Shuhui Xiong, Zhaoyi Wu, Xingde Wang, Yamin Gong, Wei‐Guo Zhu, Xingzhi Xu · 2024 · Autophagy
  7. Disrupted autophagy undermines skeletal muscle adaptation and integrity
    Elliot J. Jokl, Gonzalo Blanco · 2016 · Mammalian Genome
  8. The ATP ase VCP /p97 functions as a disaggregase against toxic Huntingtin‐exon1 aggregates
    Debasish Kumar Ghosh, Ajit Roy, Akash Ranjan · 2018 · FEBS Letters
  9. IBMPFD Disease-Causing Mutant VCP/p97 Proteins Are Targets of Autophagic-Lysosomal Degradation
    Oznur Bayraktar, Özlem Oral, Nur Mehpare Kocatürk, Yunus Akkoç, Karin Eberhart, Ali Koşar, Devrim Gözüaçık · 2016 · PLoS ONE
  10. Heteromeric p97/p97R155C Complexes Induce Dominant Negative Changes in Wild-Type and Autophagy 9-Deficient Dictyostelium strains
    Khalid Arhzaouy, Karl-Heinz Strucksberg, Sze Man Tung, Karthikeyan Tangavelou, Maria Stumpf, Jan Faix, Rolf Schröder, Christoph Stephan Clemen, Ludwig Eichinger · 2012 · PLoS ONE
  11. Systemic Analysis of miRNAs in PD Stress Condition: miR-5701 Modulates Mitochondrial–Lysosomal Cross Talk to Regulate Neuronal Death
    Paresh Prajapati, Lakshmi Sripada, Kritarth Singh, Milton Roy, Khyati Bhatelia, Pooja Dalwadi, Rajesh Singh · 2017 · Molecular Neurobiology
  12. Altered expression of p97/Valosin containing protein and impaired autophagy in preeclamptic human placenta
    Asker Zeki Özsoy, Sevil Çaylı, Cansu Sahin, Seda Ocaklı, Tuba Özdemir Sancı, İlhan Bahri Delibaş · 2018 · Placenta
  13. Rare Inherited forms of Paget’s Disease and Related Syndromes
    Stuart H. Ralston, J. Paul Taylor · 2019 · Calcified Tissue International
  14. The Machado–Joseph disease deubiquitylase ataxin‐3 interacts with LC3C/GABARAP and promotes autophagy
    Laura K. Herzog, Éva Kevei, Ricardo Marchante, Claudia Böttcher, Christian Bindesbøll, Alf Håkon Lystad, Annika Pfeiffer, Maria E. Gierisch, Florian A. Salomons, Anne Simonsen et al. · 2019 · Aging Cell
  15. White Spot Syndrome Virus Benefits from Endosomal Trafficking, Substantially Facilitated by a Valosin-Containing Protein, To Escape Autophagic Elimination and Propagate in the Crustacean Cherax quadricarinatus
    Chuang Meng, Ling-ke Liu, Dong-Li Li, Rui-Lin Gao, Wei-Wei Fan, Ke-Jian Wang, Han‐Ching Wang, Hai‐Peng Liu · 2020 · Journal of Virology
  16. Cdc48p/p97-mediated regulation of mitochondrial morphology is Vms1p-independent
    Masatoshi Esaki, Teru Ogura · 2012 · Journal of Structural Biology
  17. The regulation of the small heat shock protein B8 in misfolding protein diseases causing motoneuronal and muscle cell death
    Cristofani, Riccardo, Rusmini, Paola, Galbiati, Mariarita, Cicardi, Maria Elena, Ferrari, Veronica, Tedesco, Barbara, Casarotto, Elena, Chierichetti, Marta, Messi, Elio, Piccolella, Margherita et al. · 2019 · Frontiers in Neuroscience
  18. Emerging roles of lysosome homeostasis (repair, lysophagy and biogenesis) in cancer progression and therapy
    Nitish Chauhan, Birija Sankar Patro · 2023 · Cancer Letters
  19. VCP gene analyses in Japanese patients with sporadic amyotrophic lateral sclerosis identify a new mutation
    Makito Hirano, Yusaku Nakamura, Kazumasa Saigoh, Hikaru Sakamoto, Shuichi Ueno, Chiharu Isono, Yoshiyuki Mitsui, Susumu Kusunoki · 2014 · Neurobiology of Aging
  20. Autophagy Dysfunction in ALS: from Transport to Protein Degradation
    Marta Cozzi, Veronica Ferrari · 2022 · Journal of Molecular Neuroscience
  21. Neuronal-Specific Overexpression of a Mutant Valosin-Containing Protein Associated with IBMPFD Promotes Aberrant Ubiquitin and TDP-43 Accumulation and Cognitive Dysfunction in Transgenic Mice
    Carlos J. Rodríguez‐Ortiz, Hitomi Hoshino, David Cheng, Liqun Liu‐Yesucevitz, Mathew M. Blurton-Jones, Benjamin L. Wolozin, Frank M. LaFerla, Masashi Kitazawa · 2013 · American Journal Of Pathology
  22. Roles of Cdc48 in Regulated Protein Degradation in Yeast
    Alexander Buchberger · 2013 · Sub-cellular biochemistry/Subcellular biochemistry
  23. Protein recycling pathways in neurodegenerative diseases
    Faisal Fecto, Y. Taylan Esengul, Teepu Siddique · 2014 · Alzheimer s Research & Therapy
  24. Valosin‐containing protein ATPase activity regulates the morphogenesis of Zika virus replication organelles and virus‐induced cell death
    Anaïs Anton, Clément Mazeaud, Wesley Freppel, Claudia Gilbert, Nicolas Tremblay, Aïssatou Aïcha Sow, Marie Roy, Ian Gaël Rodrigue‐Gervais, Laurent Chatel‐Chaix · 2021 · Cellular Microbiology
  25. Current Knowledge of Endolysosomal and Autophagy Defects in Hereditary Spastic Paraplegia
    Liriopé Toupenet Marchesi, Marion Leblanc, Giovanni Stévanin · 2021 · Cells
  26. Modulating Macroautophagy: A Neuronal Perspective
    Christopher W Johnson, Thomas James Melia, Ai Yamamoto · 2012 · Future Medicinal Chemistry
  27. Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer
    Cuige Zhu, Anna M. Rogers, Karama Asleh, Jennifer Won, Dongxia Gao, Samuel C. Y. Leung, Shan Li, Kiran R. Vij, Jian Zhu, Jason M. Held et al. · 2020 · Cell Reports
  28. The Biogenesis of Dengue Virus Replication Organelles Requires the ATPase Activity of Valosin-Containing Protein
    Clément Mazeaud, Anaïs Anton, Felix Pahmeier, Aïssatou Aïcha Sow, Berati Cerikan, Wesley Freppel, Mirko Cortese, Ralf F. W. Bartenschlager, Laurent Chatel‐Chaix · 2021 · Viruses
  29. AKT/mTOR and c-Jun N-terminal kinase signaling pathways are required for chrysotile asbestos-induced autophagy
    Ziying Lin, Tie Liu, David W. Kamp, Yahong Wang, Huijuan He, Xu Zhou, Donghong Li, Lawei Yang, Bin Zhao, Gang Liu · 2014 · Free Radical Biology and Medicine
  30. Impact of Air Pollutants on Oxidative Stress in Common Autophagy-Mediated Aging Diseases
    Mohamed Numan, Jacques P. Brown, Laëtitia Michou · 2015 · International Journal of Environmental Research and Public Health
  31. Valosin-Containing Protein (VCP): A Review of Its Diverse Molecular Functions and Clinical Phenotypes
    Carly Sabine Pontifex, Mashiat Zaman, Roberto Dalto Fanganiello, Timothy E. Shutt, Gerald Pfeffer · 2024 · International Journal of Molecular Sciences
  32. Endoplasmic Reticulum-associated Degradation Controls Cell Surface Expression of γ-Aminobutyric Acid, Type B Receptors
    Khaled Zemoura, Marisa Schenkel, Mario A. Acuña, Gonzalo E. Yévenes, Hanns Ulrich Zeilhofer, Dietmar Benke · 2013 · Journal of Biological Chemistry
  33. Rotavirus Increases Levels of Lipidated LC3 Supporting Accumulation of Infectious Progeny Virus without Inducing Autophagosome Formation
    Francesca Arnoldi, Giuditta De Lorenzo, Miguel Mano, Elisabeth M. Schraner, Peter Wild, Catherine Eichwald, Óscar R. Burrone · 2014 · PLoS ONE
  34. Inadequate fine-tuning of protein synthesis and failure of amino acid homeostasis following inhibition of the ATPase VCP/p97
    Katarzyna Parzych, Tamara M. Chinn, Z Chen, S Loaiza, Florentina Porsch, Gabriel N. Valbuena, Maurits F. Kleijnen, Anastasios Karadimitris, Eileen Gentleman, Hector C. Keun et al. · 2015 · Cell Death and Disease
  35. Participation of selenoproteins localized in the ER in the processes occurring in this organelle and in the regulation of carcinogenesis-associated processes
    Elena Gennadyevna Varlamova · 2018 · Journal of Trace Elements in Medicine and Biology
  36. Autophagy and lysosomal pathways in nervous system disorders
    Baris Bingol · 2018 · Molecular and Cellular Neuroscience
  37. Cdc48/VCP and Endocytosis Regulate TDP-43 and FUS Toxicity and Turnover
    Guangbo Liu, Aaron T. Byrd, Fen Pei, Allison Buchanan, Eman Basha, Amanda Warner, J. Ross Buchan · 2019 · Molecular and Cellular Biology
  38. Autophagy and neurodegeneration: Unraveling the role of C9ORF72 in the regulation of autophagy and its relationship to ALS-FTD pathology
    Rim Diab, Federica Pilotto, Smita Saxena · 2023 · Frontiers in Cellular Neuroscience
  39. VCP Machinery Mediates Autophagic Degradation of Empty Argonaute
    Hotaka Kobayashi, Keisuke Shoji, Kaori Kiyokawa, Lumi Negishi, Yukihide Tomari · 2019 · Cell Reports
  40. Pathomechanism Heterogeneity in the Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Disease Spectrum: Providing Focus Through the Lens of Autophagy
    Rebecca Casterton, Rachel J. Hunt, Manolis Fanto · 2020 · Journal of Molecular Biology
  41. In vitro studies in VCP-associated multisystem proteinopathy suggest altered mitochondrial bioenergetics
    Angèle Nalbandian, Katrina J. Llewellyn, Arianna Ericka Gómez, Naomi Walker, Hailing Su, Andrew Dunnigan, Marilyn Chwa, Jouni Vesa, M. Cristina Kenney, Virginia E. Kimonis · 2015 · Mitochondrion
  42. Hepatic cytochromes P450: structural degrons and barcodes, posttranslational modifications and cellular adapters in the ERAD-endgame
    Sung‐Mi Kim, Yongqiang Wang, Noushin Nabavi, Yi Liu, Maria Almira Correia · 2016 · Drug Metabolism Reviews
  43. Impaired Autophagy in Motor Neurons: A Final Common Mechanism of Injury and Death
    Maria Alejandra Gonzalez Porras, Gary Charles Sieck, Carlos Bernardo Mantilla · 2018 · Physiology
  44. Stress granules in colorectal cancer: Current knowledge and potential therapeutic applications
    Noémie Legrand, Dan A. Dixon, Cyril Sobolewski · 2020 · World Journal of Gastroenterology
  45. Aggrephagy Deficiency in the Placenta: A New Pathogenesis of Preeclampsia
    Akitoshi Nakashima, Tomoko Shima, Sayaka Tsuda, Aiko Aoki, Mihoko Kawaguchi, Atsushi Furuta, Ippei Yasuda, Satoshi Yoneda, Akemi Yamaki‐Ushijima, Shi‐Bin Cheng et al. · 2021 · International Journal of Molecular Sciences
  46. Clinical and Molecular Aspects of Motor Neuron Disease
    Johnathan Cooper‐Knock, Thomas Michael Jenkins, Pamela J. Shaw · 2013 · Colloquium Series on Genomic and Molecular Medicine
  47. Cdc48-independent proteasomal degradation coincides with a reduced need for ubiquitylation
    Daniela Gödderz, Christian Heinen, Francesco P. Marchese, Tilman Kurz, Klára Ács, Nico P. Dantuma · 2015 · Scientific Reports
  48. The N-terminal Region of the Ubiquitin Regulatory X (UBX) Domain-containing Protein 1 (UBXD1) Modulates Interdomain Communication within the Valosin-containing Protein p97
    Franziska Trusch, Anja Matena, Maja Vuk, Lisa Koerver, Helene Knævelsrud, Paul S. Freemont, Hemmo H Meyer, Peter Bayer · 2015 · Journal of Biological Chemistry
  49. The interplay between aging‐associated loss of protein homeostasis and extracellular vesicles in neurodegeneration
    Francesc Xavier Guix · 2019 · Journal of Neuroscience Research
  50. Dysregulated proteostasis network in neuronal diseases
    Ching-San Tseng, Yu-Wen Chao, Yi-Hsiang Liu, Yi‐Shuian Huang, Hsu‐Wen Chao · 2023 · Frontiers in Cell and Developmental Biology
  51. Amyotrophic Lateral Sclerosis Pathogenesis Converges on Defects in Protein Homeostasis Associated with TDP-43 Mislocalization and Proteasome-Mediated Degradation Overload
    Guang Lin, Dongxue Mao, Hugo Jozef Bellen · 2016 · Current topics in developmental biology/Current Topics in Developmental Biology
  52. Macrolide Antibiotics Exhibit Cytotoxic Effect under Amino Acid-Depleted Culture Condition by Blocking Autophagy Flux in Head and Neck Squamous Cell Carcinoma Cell Lines
    Kazuhiro Hirasawa, Shota Moriya, Kana Miyahara, Hiromi Kazama, Ayako Hirota, Jun Takemura, Akihisa Abe, Masato Inazu, Masaki Hiramoto, Kiyoaki Tsukahara et al. · 2016 · PLoS ONE
  53. MMD-associated RNF213 SNPs encode dominant-negative alleles that globally impair ubiquitylation
    Abhishek Bhardwaj, Robert S. Banh, Wei Zhang, Sachdev S. Sidhu, Benjamin G. Neel · 2022 · Life Science Alliance
  54. Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish
    Anja Bühler, Monika Kustermann, Tiziana Bummer, Wolfgang Rottbauer, Marco Sandri, Steffen Just · 2016 · International Journal of Molecular Sciences
  55. Derlin-1 Regulates Mutant VCP-Linked Pathogenesis and Endoplasmic Reticulum Stress-Induced Apoptosis
    Cyong‐Jhih Liang, Ya‐Chu Chang, Henry C. Chang, Chung-Kang Wang, Yu-Chien Hung, Ying-Er Lin, Chia-Ching Chan, Chun‐Hong Chen, Hui-Yun Chang, Tzu‐Kang Sang · 2014 · PLoS Genetics
  56. Small-Molecule Modulators of the ATPase VCP/p97 Affect Specific p97 Cellular Functions
    Ainoa Figuerola Conchas, Jacques Saarbach, Jean‐Pierre Daguer, Adeline Cieren, Sofía Barluenga, Nicolas Winssinger, Monica Gotta · 2019 · ACS Chemical Biology
  57. Defects of Nutrient Signaling and Autophagy in Neurodegeneration
    Jon Ondaro, Haizea Hernández-Eguiazu, Maddi Garciandia-Arcelus, Raúl Loera‐Valencia, Laura Rodríguez-Gómez, Andrés Jiménez-Zúñiga, Julen Goikolea, Patricia Rodriguez‐Rodriguez, Javier Ruiz‐Martínez, Fermín Moreno et al. · 2022 · Frontiers in Cell and Developmental Biology
  58. Eight proteins play critical roles in RCC with bone metastasis via mitochondrial dysfunction
    Jiang Wang, Xiaolin Zhao, Jun Qi, Caihong Yang, Hao Cheng, Ye Ren, Lei Huang · 2015 · Clinical & Experimental Metastasis
  59. Protective Role of Cell Division Cycle 48 (CDC48) Protein against Neurodegeneration via Ubiquitin-Proteasome System Dysfunction during Zebrafish Development
    Shintaro Imamura, Takeshi Yabu, Michiaki Yamashita · 2012 · Journal of Biological Chemistry
  60. From neurodevelopment to neurodegeneration: the interaction of neurofibromin and valosin-containing protein/p97 in regulation of dendritic spine formation
    Yi‐Ping Hsueh · 2012 · Journal of Biomedical Science
  61. TDP-43 proteinopathy in frontotemporal lobar degeneration and amyotrophic lateral sclerosis: From pathomechanisms to therapeutic strategies
    Pei‐Chuan Ho, Tsung‐Chi Hsieh, Kuen‐Jer Tsai · 2024 · Ageing Research Reviews
  62. Porcine Reproductive and Respiratory Syndrome Virus nsp5 Induces Incomplete Autophagy by Impairing the Interaction of STX17 and SNAP29
    Yanrong Zhou, Yang Li, Ran N. Tao, Jia Li, Liurong Fang, Shaobo Xiao · 2023 · Microbiology Spectrum
  63. The Myoblast C2C12 Transfected with Mutant Valosin-Containing Protein Exhibits Delayed Stress Granule Resolution on Oxidative Stress
    Carlos J. Rodríguez‐Ortiz, Julio C. Flores Servin, Joanna Valenzuela, Gema J. Rodriguez, Joannee Zumkehr, Diana N. Tran, Virginia E. Kimonis, Masashi Kitazawa · 2016 · American Journal Of Pathology
  64. EVI/WLS function is regulated by ubiquitylation and is linked to ER-associated degradation by ERLIN2
    Lucie Wolf, Annika Lambert, Julie Haenlin, Michael Boutros · 2021 · Journal of Cell Science
  65. Defective proteostasis in induced pluripotent stem cell models of frontotemporal lobar degeneration
    Mahali, Sidhartha, Martinez, Rita, King, Melvin, Verbeck, Anthony, Harari, Oscar, Benitez, Bruno A., Horie, Kanta, Sato, Chihiro, Temple, Sally, Karch, Celeste M. · 2022 · Translational Psychiatry
  66. Gene Expression Profiling in Tibial Muscular Dystrophy Reveals Unfolded Protein Response and Altered Autophagy
    Mark Screen, Olayinka Raheem, Jeanette Holmlund-Hampf, Per Harald Jonson, Sanna Huovinen, Peter Hackman, Bjarne Udd · 2014 · PLoS ONE
  67. Evidence of TRK-Fused Gene (TFG1) function in the ubiquitin–proteasome system
    Takuya Yagi, Daisuke Ito, Norihiro Suzuki · 2014 · Neurobiology of Disease
  68. The Type II Deiodinase Is Retrotranslocated to the Cytoplasm and Proteasomes via p97/Atx3 Complex
    Rafael Arrojo e Drigo, Péter Egri, Sungro Jo, Balázs Gereben, Antonio Carlos Bianco · 2013 · Molecular Endocrinology
  69. Valosin-containing protein (VCP): structure, functions, and implications in neurodegenerative diseases
    Bo Kyoung Yeo, Seong‐Woon Yu · 2016 · Animal Cells and Systems
  70. Potential skin involvement in ALS: revisiting Charcot’s observation – a review of skin abnormalities in ALS
    Bastien Paré, François Gros‐Louis · 2017 · Reviews in the Neurosciences
  71. Depletion of Ubiquilin induces an augmentation in soluble ubiquitinated Drosophila TDP-43 to drive neurotoxicity in the fly
    Salinee Jantrapirom, Luca Lo Piccolo, Hideki Yoshida, Masamitsu Yamaguchi · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  72. Novel strategies in Parkinson’s disease treatment: a review
    Charles L. Mitchell, Dmitry Kurouski · 2024 · Frontiers in Molecular Neuroscience
  73. USP11 induce resistance to 5-Fluorouracil in Colorectal Cancer through activating autophagy by stabilizing VCP
    Hongze Sun, Rangrang Wang, Yuan Liu, Haitao Mei, Xueni Liu, Zhihai Peng · 2021 · Journal of Cancer
  74. CRISPR/Cas9-engineered Drosophila knock-in models to study VCP diseases
    Jordan M. Wall, Ankita Basu, Elizabeth R. M. Zunica, Olga S. Dubuisson, Kathryn P. Belmont, Joshua P. Broussard, John P. Kirwan, Christopher L. Axelrod, Alyssa E. Johnson · 2021 · Disease Models & Mechanisms
  75. The Emerging Role of Stress Granules in Hepatocellular Carcinoma
    Dobrochna Dolicka, Michelangelo Foti, Cyril Sobolewski · 2021 · International Journal of Molecular Sciences
  76. Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter
    Martin L. Read, Katie Brookes, Caitlin E.M. Thornton, Alice Fletcher, Hannah R. Nieto, Mohammed Alshahrani, Rashida Khan, Patricia Borges de Souza, Ling Zha, Jamie Webster et al. · 2021 · Cell chemical biology
  77. Implications of Valosin-containing Protein in Promoting Autophagy to Prevent Tau Aggregation
    Subashchandrabose Chinnathambi, Nalini Vijay Gorantla · 2021 · Neuroscience
  78. Emerging mechanisms of mRNP remodeling regulation
    Chyi‐Ying A. Chen, Ann‐Bin Shyu · 2014 · Wiley Interdisciplinary Reviews - RNA
  79. Autophagy and mitophagy at the synapse and beyond: implications for learning, memory and neurological disorders
    Jiayi Lu, Damian Nicolas Di Florio, Patricia Boya, Sandra Maday, Wolfdieter Springer, Charleen T. Chu · 2025 · Autophagy
  80. Methylation of the PTPRO gene in human hepatocellular carcinoma and identification of VCP as its substrate
    Shu‐Hao Hsu, Tasneem Motiwala, Satavisha Roy, Rainer Claus, Mufaddal Mustafa, Christoph Plass, Michael A. Freitas, Kalpana Ghoshal, Samson T. Jacob · 2013 · Journal of Cellular Biochemistry
  81. The involvement of endoplasmic reticulum formation and protein synthesis efficiency in VCP- and ATL1-related neurological disorders
    Yu‐Tzu Shih, Yi‐Ping Hsueh · 2018 · Journal of Biomedical Science
  82. Discovery of Novel Cinchona‐Alkaloid‐Inspired Oxazatwistane Autophagy Inhibitors
    Luca Laraia, Kosuke Ohsawa, Georgios Konstantinidis, Lucas Robke, Yao‐Wen Wu, Kamal Kumar, Herbert Waldmann · 2017 · Angewandte Chemie
  83. The role of p62/SQSTM1 in sporadic inclusion body myositis
    Satoshi Nakano, Mitsuaki Oki, Hirofumi Kusaka · 2016 · Neuromuscular Disorders
  84. Pathogenic variants of Valosin‐containing protein induce lysosomal damage and transcriptional activation of autophagy regulators in neuronal cells
    Veronica Ferrari, Riccardo Cristofani, M.E. Cicardi, B. Tedesco, V. Crippa, Marta Chierichetti, Elena Casarotto, Marta Cozzi, Francesco Mina, M. Galbiati et al. · 2022 · Neuropathology and Applied Neurobiology
  85. An emerging role for stress granules in neurodegenerative disease and hearing loss
    Jack L. Martin, Sally J. Dawson, Jonathan E. Gale · 2022 · Hearing Research
  86. De Novo Prion Aggregates Trigger Autophagy in Skeletal Muscle
    Shivanjali Joshi-Barr, Cyrus K. Bett, Wei-Chieh Jerry Chiang, Margarita Trejo, Hans Hilmar Goebel, Beata Sikorska, Pawel Piotr Liberski, Alex J. Raeber, Jonathan H. Lin, Eliezer Masliah et al. · 2013 · Journal of Virology
  87. Structural and functional deviations in disease-associated p97 mutants
    Wai Kwan Tang, Di Xia · 2012 · Journal of Structural Biology
  88. The fine-tuning of proteolytic pathways in Alzheimer’s disease
    Cecarini, Valentina, Bonfili, Laura, Cuccioloni, Massimiliano, Mozzicafreddo, Matteo, Angeletti, Mauro, Keller, Jeffrey N., Eleuteri, Anna Maria · 2016 · Cellular and Molecular Life Sciences
  89. Culling sick mitochondria from the herd
    Leo J. Pallanck · 2010 · The Journal of Cell Biology
  90. PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805
    Yunpeng Bai, Guimei Yu, Hongming Zhou, Ovini Amarasinghe, Yuan Zhou, Peipei Zhu, Qinglin Li, Lujuan Zhang, Frederick Nguele Meke, Yiming Miao et al. · 2022 · Autophagy
  91. Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis
    Konstantinos Tsioras, Kevin C. Smith, Seby Louis Edassery, Mehraveh Garjani, Yichen Li, Chloe Williams, Elizabeth D. McKenna, Wenxuan Guo, Anika P. Wilen, Timothy J. Hark et al. · 2023 · Cell Reports
  92. VBP1 facilitates proteasome and autophagy‐mediated degradation of MutS homologue hMSH4
    Yang Xu, Chengtao Her · 2013 · The FASEB Journal
  93. The Amyotrophic Lateral Sclerosis M114T PFN1 Mutation Deregulates Alternative Autophagy Pathways and Mitochondrial Homeostasis
    Elisa Teyssou, Laura Chartier, Delphine Roussel, Nirma D. Perera, Ivan Nemazanyy, Dominique Langui, Mélanie Albert, Thierry Larmonier, Safaa Saker, François Salachas et al. · 2022 · International Journal of Molecular Sciences
  94. The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation
    Bajc Česnik, Ana, Motaln, Helena, Rogelj, Boris · 2020 · Cells
  95. Tau accumulation is cleared by the induced expression of VCP via autophagy
    Hoi-Khoanh Giong, Seung Jae Hyeon, Jae-Geun Lee, Hyun-Ju Cho, Uiyeol Park, Thor D. Stein, Jung-Hee Lee, Kweon Yu, Hoon Ryu, Jeong-Soo Lee · 2024 · Acta Neuropathologica
  96. Hepatic COX1 loss leads to impaired autophagic flux and exacerbates nonalcoholic steatohepatitis
    Qian Yu, Chang Li, Qinghui Niu, Jigang Wang, Zhaodi Che, Ke Lei, He Ren, Boyi Ma, Yixing Ren, Pingping Luo et al. · 2023 · Acta Pharmaceutica Sinica B
  97. VCP activator reverses nuclear proteostasis defects and enhances TDP-43 aggregate clearance in multisystem proteinopathy models
    Jessica M. Phan, Benjamin C. Creekmore, Aivi T. Nguyen, Darya D. Bershadskaya, Nabil F. Darwich, Carolyn N. Mann, Edward B. Lee · 2024 · Journal of Clinical Investigation
  98. The nascent polypeptide-associated complex is essential for autophagic flux
    Bin Guo, Jie Sheng Huang, Wenxian Wu, Du Feng, Xiaochen Wang, Yingyu Chen, Hong Zhang · 2014 · Autophagy
  99. Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex
    Xiaojing Li, Yuanyuan Zhang, Yuhua Fu, Hao Zhang, He-xuan Li, Quanfu Li, Hailing Li, Renke Tan, Chen-xiao Jiang, Wei Jiang et al. · 2021 · Acta Pharmacologica Sinica
  100. Valosin-Containing Protein Gene Mutations: Cellular Phenotypes Relevant to Neurodegeneration
    Karen S. Poksay, David T. Madden, Anna K. Peter, Kayvan Reza Niazi, Surita Banwait, Danielle Crippen, Dale E. Bredesen, Rammohan V. Rao · 2011 · Journal of Molecular Neuroscience