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A comprehensive siRNA screen for kinases that suppress macroautophagy in optimal growth conditions
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“Accordingly, high-content imaging analysis methods enable quantification of GFP-LC3 puncta (or overall fluorescence intensity) in thousands of cells per sample (e.g.see refs.[336,354,412]).”
From Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 (2021) · cites this paper as [336]
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“Although less work has been done on post-transcriptional regulation, several studies implicate microRNAs in controlling the expression of proteins associated with autophagy [334-336, 984-987].”
From Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 (2021) · cites this paper as [336]
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Termination of autophagy and reformation of lysosomes regulated by mTOR
Yu, L., McPhee, C. K., Zheng, L., Mardones, G. A., Rong, Y., Peng, J., Mi, N., Zhao, Y., Liu, Z., Wan, F., et al. (2010) · Nature · doi:10.1038/nature09076 · Cited by 1,544
Heat Shock Protein 70 Promotes Cell Survival by Inhibiting Lysosomal Membrane Permeabilization
Nylandsted, J., Gyrd-Hansen, M., Danielewicz, A., Fehrenbacher, N., Lademann, U., Høyer-Hansen, M., Weber, E., Multhoff, G., Rohde, M., & Jäättelä, M. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20040531 · Cited by 545
Self-citationTAK1 activates AMPK‐dependent cytoprotective autophagy in TRAIL‐treated epithelial cells
Herrero‐Martín, G., Høyer‐Hansen, M., García‐García, C., Fumarola, C., Farkas, T., López‐Rivas, A., & Jäättelä, M. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.8 · Cited by 400
Self-citationAutophagy: An emerging target for cancer therapy
Høyer-Hansen, M., & Jäättelä, M. (2008) · Autophagy · doi:10.4161/auto.5921 · Cited by 192 · cited 1×
“Yet, human cancer cells are often deficient for autophagy-activating proteins while having autophagy-inhibiting proteins activated suggesting a role for autophagy as a barrier for the transformation process.(1,9,10) Accordingly, it is still unclear whether we should inhibit or activate autophagy in cancer treatment.”
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RNF166 determines recruitment of adaptor proteins during antibacterial autophagy
Heath, R. J., Goel, G., Baxt, L. A., Rush, J. S., Mohanan, V., Paulus, G. L. C., Jani, V., Lassen, K. G., & Xavier, R. J. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.11.005 · Cited by 108
“…of each of the 12 candidate E3 ligases with a curated list of known autophagy-associated genes derived from published databases (Huttlin et al., 2015; Lipinski et al., 2010; McKnight et al., 2012; Orvedahl et al., 2011; Sorbara and Girardin, 2015; Szyniarowski et al., 2011; Figure 1E; Table S2).”
Background
Metadata
- Authors
- Szyniarowski, P., Corcelle-Termeau, E., Farkas, T., Høyer-Hansen, M., Nylandsted, J., Kallunki, T., & Jäättelä, M.
- Venue
- Autophagy
- Publisher
- Informa UK Limited
- Published
- 2011-08
- Volume
- 7
- Issue
- 8
- Pages
- 892-903
- ISSN
- 1554-8627
- 1554-8635
- Cited by
- 79
- References
- 6
- Language
- en
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