The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Atorvastatin induces autophagy in prostate cancer PC3 cells through activation of LC3 transcription
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Synovial fibroblasts obtained from patients with rheumatoid arthritis also exhibit a significant upregulation of SQSTM1 with concomitant increased autophagy flux [575].”
From Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 (2021) · cites this paper as [575]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Rab GTPases as coordinators of vesicle traffic
Stenmark, H. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2728 · Cited by 3,413
ERK and cell death: mechanisms of ERK-induced cell death--apoptosis, autophagy and senescence
Cagnol, S., & Chambard, J. (2010) · The FEBS Journal · doi:10.1111/j.1742-4658.2009.07366.x · Cited by 1,290
Research works printed but not linked: 33
- Parikh A, Childress C, Deitrick K, Lin Q, Rukstalis D, Yang W. Statin-induced autophagy by inhibition of geranylgeranyl biosynthesis in prostate cancer PC3 cells. Prostate 2010; 70:971-81; PMID: 20135644; DOI:10.1002/pros.21131. · DOI
- Khosravi-Far R, Lutz RJ, Cox AD, Conroy L, Bourne JR, Sinensky M, et al. Isoprenoid modification of rab proteins terminating in CC or CXC motifs. Proc Natl Acad Sci USA 1991; 88:6264-8; PMID: 1648736; DOI:10.1073/pnas.88.14.6264. · DOI
- Kinsella BT, Maltese WA. Rab GTP-binding proteins with three different carboxyl-terminal cysteine motifs are modified in vivo by 20-carbon isoprenoids. J Biol Chem 1992; 267:3940-5; PMID: 1740442.
- Wu YT, Tan HL, Huang Q, Kim YS, Pan N, Ong WY, et al. Autophagy plays a protective role during zVAD-induced necrotic cell death. Autophagy 2008; 4:457-66; PMID: 18253089.
- Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, et al. LC3, a mammalian homo- logue of yeast Apg8p, is localized in autophago- some membranes after processing. EMBO J 2000; 19:5720-8; PMID: 11060023; DOI:10.1093/ emboj/19.21.5720. · DOI · Paper page
- Cheng Y, Qiu F, Tashiro S, Onodera S, Ikejima T. ERK and JNK mediate TNFalpha-induced p53 acti- vation in apoptotic and autophagic L929 cell death. Biochem Biophys Res Commun 2008; 376:483-8; PMID: 18796294; DOI:10.1016/j.bbrc.2008.09.018. · DOI
- Shintani T, Klionsky DJ. Autophagy in health and dis- ease: a double-edged sword. Science 2004; 306:990-5; PMID: 15528435; DOI:10.1126/science.1099993. · DOI
- Hippert MM, O'Toole PS, Thorburn A. Autophagy in cancer: good, bad or both? Cancer Res 2006; 66:9349- 51; PMID: 17018585; DOI:10.1158/0008-5472. CAN-06-1597. · DOI
- Li DD, Wang LL, Deng R, Tang J, Shen Y, Guo JF, et al. The pivotal role of c-Jun NH 2 -terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells. Oncogene 2009; 28:886-98; PMID: 19060920; DOI:10.1038/ onc.2008.441. · DOI
- Chen SY, Chiu LY, Maa MC, Wang JS, Chien CL, Lin WW. zVAD-induced autophagic cell death requires c-Src-dependent ERK and JNK activation and reactive oxygen species generation. Autophagy 2011; 7:217-28; PMID: 21127402; DOI:10.4161/auto.7.2.14212. · DOI
- Ghosh PM, Ghosh-Choudhury N, Moyer ML, Mott GE, Thomas CA, Foster BA, et al. Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line. Oncogene 1999; 18:4120-30; PMID: 10435593; DOI:10.1038/sj.onc.1202792. · DOI
- Sarrabayrouse G, Synaeve C, Leveque K, Favre G, Tilkin-Mariamé AF. Statins stimulate in vitro mem- brane FasL expression and lymphocyte apoptosis through RhoA/ROCK pathway in murine melanoma cells. Neoplasia 2007; 9:1078-90; PMID: 18084615; DOI:10.1593/neo.07727. · DOI
- Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation. Science 2000; 290:1717-21; PMID: 11099404; DOI:10.1126/sci- ence.290.5497.1717. · DOI
- Yorimitsu T, Klionsky DJ. Autophagy: molecular machinery for self-eating. Cell Death Differ 2005; 12:1542-52; PMID: 16247502; DOI:10.1038/ sj.cdd.4401765. · DOI
- Mortimore GE, Pösö AR. Intracellular protein catabo- lism and its control during nutrient deprivation and sup- ply. Annu Rev Nutr 1987; 7:539-64; PMID: 3300746; DOI:10.1146/annurev.nu.07.070187.002543. · DOI
- Uchiyama Y, Shibata M, Koike M, Yoshimura K, Sasaki M. Autophagy-physiology and pathophysiol- ogy. Histochem Cell Biol 2008; 129:407-20; PMID: 18320203; DOI:10.1007/s00418-008-0406-y. · DOI
- Noda T, Ohsumi Y. Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast. J Biol Chem 1998; 273:3963-6; PMID: 9461583; DOI:10.1074/ jbc.273.7.3963. · DOI
- Kamada Y, Funakoshi T, Shintani T, Nagano K, Ohsumi M, Ohsumi Y. Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J Cell Biol 2000; 150:1507-13; PMID: 10995454; DOI:10.1083/jcb.150.6.1507. · DOI · Paper page
- Petiot A, Ogier-Denis E, Blommaart EF, Meijer AJ, Codogno P. Distinct classes of phosphatidylinositol- 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. J Biol Chem 2000; 275:992-8; PMID: 10625637; DOI:10.1074/ jbc.275.2.992. · DOI
- Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A, et al. Autophagosome formation from membrane compartments enriched in phos- phatidylinositol-3-phosphate and dynamically con- nected to the endoplasmic reticulum. J Cell Biol 2008; 182:685-701; PMID: 18725538; DOI:10.1083/ jcb.200803137. · DOI · Paper page
- Proikas-Cezanne T, Waddell S, Gaugel A, Frickey T, Lupas A, Nordheim A. WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein fam- ily, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy. Oncogene 2004; 23:9314-25; PMID: 15602573; DOI:10.1038/ sj.onc.1208331. · DOI · Paper page
- Demierre MF, Higgins PD, Gruber SB, Hawk E, Lippman SM. Statins and cancer prevention. Nat Rev Cancer 2005; 5:930-42; PMID: 16341084; DOI:10.1038/nrc1751. · DOI
- Platz EA, Leitzmann MF, Visvanathan K, Rimm EB, Stampfer MJ, Willett WC, et al. Statin drugs and risk of advanced prostate cancer. J Natl Cancer Inst 2006; 98:1819-25; PMID: 17179483; DOI:10.1093/jnci/ djj499. · DOI
- Loeb S, Kan D, Helfand BT, Nadler RB, Catalona WJ. Is statin use associated with prostate cancer aggressive- ness? BJU Int 2010; 105:1222-5; PMID: 19888973; DOI:10.1111/j.1464-410X.2009.09007.x. · DOI
- Hamilton RJ, Goldberg KC, Platz EA, Freedland SJ. The influence of statin medications on prostate-specific antigen levels. J Natl Cancer Inst 2008; 100:1511-8; PMID: 18957682; DOI:10.1093/jnci/djn362. · DOI
- Jones KD, Couldwell WT, Hinton DR, Su Y, He S, Anker L, et al. Lovastatin induces growth inhibi- tion and apoptosis in human malignant glioma cells. Biochem Biophys Res Commun 1994; 205:1681-7; PMID: 7811252; DOI:10.1006/bbrc.1994.2861. · DOI
- Pérez-Sala D, Mollinedo F. Inhibition of isoprenoid biosynthesis induces apoptosis in human promyelo- cytic HL-60 cells. Biochem Biophys Res Commun 1994; 199:1209-15; PMID: 8147861; DOI:10.1006/ bbrc.1994.1359. · DOI
- Glynn SA, O'Sullivan D, Eustace AJ, Clynes M, O'Donovan N. The 3-hydroxy-3-methylglutaryl-coen- zyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells. BMC Cancer 2008; 8:9; PMID: 18199328; DOI:10.1186/1471-2407-8-9. · DOI
- Hoque A, Chen H, Xu XC. Statin induces apoptosis and cell growth arrest in prostate cancer cells. Cancer Epidemiol Biomarkers Prev 2008; 17:88-94; PMID: 18199714; DOI:10.1158/1055-9965.EPI-07-0531. · DOI
- Wong WW, Tan MM, Xia Z, Dimitroulakos J, Minden MD, Penn LZ. Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin. Clin Cancer Res 2001; 7:2067-75; PMID: 11448925.
- van de Donk NW, Kamphuis MM, van Kessel B, Lokhorst HM, Bloem AC. Inhibition of protein gera- nylgeranylation induces apoptosis in myeloma plasma cells by reducing Mcl-1 protein levels. Blood 2003; 102:3354-62; PMID: 12855556; DOI:10.1182/ blood-2003-03-0970. · DOI
- Johnson TE, Zhang X, Bleicher KB, Dysart G, Loughlin AF, Schaefer WH, et al. Statins induce apop- tosis in rat and human myotube cultures by inhibit- ing protein geranylgeranylation but not ubiquinone. Toxicol Appl Pharmacol 2004; 200:237-50; PMID: 15504460; DOI:10.1016/j.taap.2004.04.010. · DOI
- Shipman CM, Croucher PI, Russell RG, Helfrich MH, Rogers MJ. The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway. Cancer Res 1998; 58:5294-7; PMID: 9850051.
Cited by
Sorted by citations
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy · doi:10.1080/15548627.2015.1100356 · Cited by 5,894
Self-citationGuidelines for the use and interpretation of assays for monitoring autophagy
Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy · doi:10.4161/auto.19496 · Cited by 3,996
Self-citationGuidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy · doi:10.1080/15548627.2020.1797280 · Cited by 2,897
Self-citation
Metadata
- Authors
- Toepfer, N., Childress, C., Parikh, A., Rukstalis, D., & Yang, W.
- Venue
- Cancer Biology & Therapy
- Publisher
- Informa UK Limited
- Published
- 2011-10-15
- Volume
- 12
- Issue
- 8
- Pages
- 691-699
- ISSN
- 1538-4047
- 1555-8576
- Cited by
- 67
- References
- 2
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review