Role of the hypoxia inducible factors HIF in iron metabolism

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Items 101–200 of 218

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2. Endotyping COPD: hypoxia-inducible factor-2 as a molecular “switch” between the vascular and airway phenotypes?
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3. FBXL5 modulates HIF-1α transcriptional activity by degradation of CITED2
   Gisela Machado-Oliveira, Eduarda M. Guerreiro, Ana Catarina Matias, João Facucho-Oliveira, Ivette Pacheco-Leyva, José Bragança · 2015 · Archives of Biochemistry and Biophysics
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5. Circulating factors are involved in hypoxia-induced hepcidin suppression
   Giulia Ravasi, Sara Pelucchi, Federico Greni, Raffaella Mariani, Andrea Giuliano, Gianfranco Parati, Laura Silvestri, Alberto Piperno · 2014 · Blood Cells Molecules and Diseases
6. Factors Affecting Doses of Roxadustat Versus Darbepoetin Alfa for Anemia in Nondialysis Patients
   Tadao Akizawa, Keiko Tanaka‐Amino, Tetsuro Otsuka, Yusuke Yamaguchi · 2021 · American Journal of Nephrology
7. Drugs activating hypoxia-inducible factors correct erythropoiesis and hepcidin levels via renal EPO induction in mice
   Taku Nakai, Yuma Iwamura, Koichiro Kato, Ikuo Hirano, Yotaro Matsumoto, Yoshihisa Tomioka, Masayuki P. Yamamoto, Norio Suzuki · 2023 · Blood Advances
8. Influence of the availability of iron during hypoxia on the genes associated with apoptotic activity and local iron metabolism in rat H9C2 cardiomyocytes and L6G8C5 skeletal myocytes
   Magdalena Dzięgała, Monika Kasztura, Kamil Aleksander Kobak, Jacek Bania, Waldemar Banasiak, Piotr P. Ponikowski, Ewa Anita Jankowska · 2016 · Molecular Medicine Reports
9. Reduced cancer mortality at high altitude: The role of glucose, lipids, iron and physical activity
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10. Impact of Hypoxia over Human Viral Infections and Key Cellular Processes
    Antonia Reyes, Luisa Fernanda Duarte, Mónica A. Farías, Eduardo I. Tognarelli, Alexis M. Kalergis, Susan M. Bueno, Pablo A. González · 2021 · International Journal of Molecular Sciences
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    Irma D Fleming, Monika A. Krezalek, Natalia Belogortseva, Alexander Zaborin, Jennifer R. DeFazio, Laxmipradha Chandrasekar, Luis A. Actis, Olga Y. Zaborina, John C. Alverdy · 2016 · The Journal of Trauma: Injury, Infection, and Critical Care
12. Signaling pathways regulating hepcidin
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13. Advances of Iron and Ferroptosis in Diabetic Kidney Disease
    Jiayi Chu, Kewu Wang, Lulu Lu, Hui Zhao, Jibo Hu, Wenbo Xiao, Qian Wu · 2024 · Kidney International Reports
14. The relationship between the preoperative plasma level of HIF-1α and clinic pathological features, prognosis in non-small cell lung cancer
    Jiabei He, Ying Hu, Ming‐Ming Hu, Siyi Zhang, Baolan Li · 2016 · Scientific Reports
15. Loss of miR-145-5p Causes Ceruloplasmin Interference with PHD-Iron Axis and HIF-2α Stabilization in Lung Adenocarcinoma-Mediated Angiogenesis
    Ying‐Ming Tsai, Kuan‐Li Wu, Yung-Yun Chang, Wei‐An Chang, Yung‐Chi Huang, Shu‐Fang Jian, Pei-Hsun Tsai, Yi-Shiuan Lin, Inn‐Wen Chong, Jen‐Yu Hung et al. · 2020 · International Journal of Molecular Sciences
16. Effect of hypoxia on the expression of iron regulatory proteins 1 and the mechanisms involved
    Qianqian Luo, Dan Wang, Min‐Yan Yu, Li Zhu · 2011 · IUBMB Life
17. Preventive preclinical efficacy of intravenously administered sphingosine-1-phosphate (S1P) in strengthening hypoxia adaptive responses to acute and sub-chronic hypobaric hypoxia
    Sonam Chawla, Babita Rahar, Rajkumar Tulswani, Shweta Saxena · 2019 · European Journal of Pharmacology
18. Hepcidin: an important iron metabolism regulator in chronic kidney disease
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19. Ironing Out the Mechanism of gp130 Signaling
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20. The role of roxadustat in chronic kidney disease patients complicated with anemia
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21. Safety of HIF prolyl hydroxylase inhibitors for anemia in dialysis patients: a systematic review and network meta-analysis
    Dinghua Chen, Yue Niu, Fei Liu, Yue Yang, Xue Wang, Ping Li, Xiangmei Chen · 2023 · Frontiers in Pharmacology
22. The efficacy and safety of roxadustat treatment for anemia in patients with kidney disease: a meta-analysis and systematic review
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23. Genetics Responses to Hypoxia and Reoxygenation Stress in Larimichthys crocea Revealed via Transcriptome Analysis and Weighted Gene Co-Expression Network
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24. Hypoxia and oxidative stress markers in pediatric patients undergoing hemodialysis: cross section study
    Enas A. Hamed, Taghrid Bahig El-Abaseri, Amany Osama Mohamed, Ahmed Ahmed, Tarek H. El‐Metwally · 2012 · BMC Nephrology
25. Changes in Iron Availability with Roxadustat in Nondialysis- and Dialysis-Dependent Patients with Anemia of CKD
    Pablo E. Pérgola, Chaim Charytan, Dustin J. Little, Stefan Tham, Lynda Anne M. Szczech, Robert Leong, Steven N. Fishbane · 2022 · Kidney360
26. Efficacy of intravenous iron treatment for chemotherapy-induced anemia: A prospective Phase II pilot clinical trial in South Korea
    Jun Ho Jang, Youjin Kim, Silvia Park, Kihyun Kım, Seok Jin Kim, Won Seog Kim, Chul Won Jung, Jeeyun Lee, Se‐Hoon Lee · 2020 · PLoS Medicine
27. A high reticulocyte count is a risk factor for the onset of metabolic dysfunction-associated steatotic liver disease: Cross-sectional and prospective studies of data of 310,091 individuals from the UK Biobank
    Peng-Cheng Ma, Qimei Li, Rui-Ning Li, Hong Hee Chang, Hao Cui, Zi-Yong Zhang, Yan Li, Lushan Xiao, Hong Zhu, Lin Zeng et al. · 2024 · Frontiers in Pharmacology
28. Anemia and Mineral Bone Disorder in Kidney Disease Patients: The Role of FGF-23 and Other Related Factors
    N. Carullo, D. Sorbo, T. Faga, Sara Pugliese, M. Zicarelli, David Costa, Nicola Ielapi, Yuri Battaglia, A. Pisani, G. Coppolino et al. · 2024 · International Journal of Molecular Sciences
29. Effects of Ovariohysterectomy and Hyperbaric Oxygen Therapy on Systemic Inflammation and Oxidation in Dogs
    Anaïs Gautier, Emily C. Graff, Lenore M. Bacek, Eric J. Fish, Amelia White, Lee E. Palmer, Kendon Wu Kuo · 2020 · Frontiers in Veterinary Science
30. Ferritin is regulated by a neuro-intestinal axis in the nematode Caenorhabditis elegans
    Leonor Romero, Veronica Zelmanovich, Zohar Abergel, B. M. Zuckerman, Maayan Shaked, Rachel Abergel, Leonid Livshits, Yoav Smith, Einav Gross · 2019 · Redox Biology
31. A Systems Biology Approach to Understanding the Pathophysiology of High-Grade Serous Ovarian Cancer: Focus on Iron and Fatty Acid Metabolism
    Anna Konstorum, Miranda L. Lynch, Suzy V. Torti, Frank M. Torti, Reinhard Laubenbacher · 2018 · OMICS A Journal of Integrative Biology
32. Increased hypoxia-inducible factor-1α in striated muscle of tumor-bearing mice
    Raymond D. Devine, Sabahattin Bicer, Peter J. Reiser, Loren E. Wold · 2017 · American Journal of Physiology-Heart and Circulatory Physiology
33. Iron overload regulate the cytokine of mesenchymal stromal cells through ROS/HIF-1α pathway in Myelodysplastic syndromes
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34. Iron Deficiency Reprograms Phosphorylation Signaling and Reduces O-GlcNAc Pathways in Neuronal Cells
    Luke N. Erber, Ang Luo, Yao Gong, Montana M. Beeson, Maolin Tu, Phu V. Tran, Yue Chen · 2021 · Nutrients
35. Iron homeostasis in the heart: Molecular mechanisms and pharmacological implications
    Jiawei Zhang, Yijing Song, You Li, Han-bin Lin, Xuexian Fang · 2022 · Journal of Molecular and Cellular Cardiology
36. Iron-deficiency anemia secondary to mutations in genes controlling hepcidin
    Milena Cau, Maria Antonietta Melis, Rita Congiu, Renzo Galanello · 2010 · Expert Review of Hematology
37. Lack of Plasma Protein Hemopexin Results in Increased Duodenal Iron Uptake
    Veronica Fiorito, Simonetta Geninatti Crich, Lorenzo Silengo, Silvio Aime, Fiorella Altruda, Emanuela Tolosano · 2013 · PLoS ONE
38. Iron as a Therapeutic Target in HFE-Related Hemochromatosis: Usual and Novel Aspects
    Olivier Loréal, Thibault Cavey, François Robin, Moussa Kenawi, Pascal Guggenbuhl, Pierre Brissot · 2018 · Pharmaceuticals
39. Targeting NRF2 and FSP1 to Overcome Ferroptosis Resistance in TSC2-Deficient and Cancer Cells
    Tasmia Tahsin, Darius K. McPhail, Jesse D. Champion, Mohammad A. M. Alzahrani, Madeleine L Hilditch, Alexandre Faris-Orr, Brian L. Calver, Darren W. Sexton, J. Cronin, Juan C. Mareque Rivas et al. · 2025 · Cancers
40. An iron-dependent metabolic vulnerability underlies VPS34-dependence in RKO cancer cells
    Marek J. Kobylarz, Jonathan M. Goodwin, Zhao B. Kang, John W. Annand, Sarah Hevi, Ellen O’Mahony, Gregory McAllister, John S. Reece-Hoyes, Qiong Wang, John Alford et al. · 2020 · PLoS ONE
41. Alcohol exposure increases manganese accumulation in the brain and exacerbates manganese-induced neurotoxicity in mice
    Murui Han, Mark Böhlke, Timothy John Maher, Jonghan Kim · 2021 · Archives of Toxicology
42. Hypoxia Pathway in Osteoporosis: Laboratory Data for Clinical Prospects
    Jianping Wang, Bin Zhao, Jingmin Che, Peng Shang · 2023 · International Journal of Environmental Research and Public Health
43. Effect of Iron Supplementation on the Expression of Hypoxia-Inducible Factor and Antioxidant Status in Rats Exposed to High-Altitude Hypoxia Environment
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44. Clinical parameters among patients in Japan with anemia and non-dialysis-dependent chronic kidney disease with and without diabetes mellitus who received roxadustat
    Tadao Akizawa, Keiko Tanaka‐Amino, Tetsuro Otsuka, Yusuke Yamaguchi · 2022 · Clinical and Experimental Nephrology
45. Pathological changes in Sertoli cells and dysregulation of divalent metal transporter 1 with iron responsive element in the testes of idiopathic azoospermia patients
    Tao Jing, P. Wang, Y. Liu, Jiao Zhao, X. Niu, X. Wang · 2017 · Andrologia
46. BPCO et érythropoïèse : interactions et conséquences
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47. High-intensity interval training in hypoxia does not affect muscle HIF responses to acute hypoxia in humans
    Stefan De Smet, Gommaar D’Hulst, Chiel Poffé, Ruud Van Thienen, Emanuele Berardi, Peter Hespel · 2018 · European Journal of Applied Physiology
48. Hypoxia-inducible factor-1α as prognostic marker
    Amin Ben Lassoued, Nathalie Beaufils, Jean-Philippe Dalès, Jean A. Gabert · 2012 · Expert Opinion on Medical Diagnostics
49. The efficacy of Roxadustat for the treatment of anemia in dialysis dependent chronic kidney disease patients: an updated systematic review and meta-analysis of randomized clinical trials
    Basel Abdelazeem, Kirellos Said Abbas, Joseph Shehata, Nahla Ahmed El‐Shahat, Nischit Baral, Pramod K. Savarapu, Arvind R. Kunadi · 2021 · Annals of Translational Medicine
50. The efficacy and safety of roxadustat for anemia in patients with dialysis-dependent chronic kidney disease: a systematic review and meta-analysis
    Qiaoqiao Zhou, Mian Mao, Jing Li, Furong Deng · 2023 · Renal Failure
51. Jian‐Pi‐Yi‐Shen Regulates EPO and Iron Recycling Protein Expressions in Anemic Rats with Chronic Kidney Disease: Accumulation of Hypoxia Inducible Factor‐2 α via ERK Signaling
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52. Iron facilitator LS 081 reduces hypoxia‐inducible factor‐1α protein and functions as anticancer agent in hepatocellular carcinoma
    Hiroki Tanaka, Zhen Li, Katsuya Ikuta, Lynda Addo, Hiroaki Akutsu, Masao Nakamura, Katsunori Sasaki, Takaaki Ohtake, Mikihiro Fujiya, Yoshihiro Torimoto et al. · 2011 · Cancer Science
53. Epoetin alfa-epbx: a new entrant into a crowded market. a historical review of the role of erythropoietin stimulating agents and the development of the first epoetin biosimilar in the United States
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54. Quantitative Proteome and Transcriptome Dynamics Analysis Reveals Iron Deficiency Response Networks and Signature in Neuronal Cells
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55. Mechanism of apoptosis involved in gastric mucosal lesions in Tibetans with high-altitude polycythemia
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56. Identification of Iron Homeostasis Genes Dysregulation Potentially Involved in Retinopathy of Prematurity Pathogenicity by Microarray Analysis
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57. Targeting hypoxia-inducible factor-1 in a hypoxidative stress model protects retinal pigment epithelium cells from cell death and metabolic dysregulation
    Annika Schubert, Maria Eduarda Lobo Barbosa da Silva, Tabea Ambrock, Orbel Terosian, Anna Malyshkina, Claudia Padberg, Safa Larafa, Johann Matschke, Joachim Fandrey, Yoshiyuki Henning · 2025 · Cell Death Discovery
58. Effect of Intravenous Iron Supplementation on Acute Mountain Sickness: A Preliminary Randomized Controlled Study
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59. Roxadustat regulates iron metabolism in dialysis-dependent and non-dialysis-dependent chronic kidney disease patients: A meta-analysis
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60. The cell-permeable iron chelator M606 inhibits MYCN-driven neuroblastoma via an E2F3-mediated response
    Ruby Pandher, Chengyuan Xue, Laura D. Gamble, Giorgio Milazzo, Simone Di Giacomo, Jayne E. Murray, Leanna Cheung, Francesca Ferrucci, Marta Palombo, Stefania Purgato et al. · 2025 · Proceedings of the National Academy of Sciences
61. The Cellular Physiology of Iron
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62. Ankaferd Influences mRNA Expression of Iron-Regulated Genes During Iron-Deficiency Anemia
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63. miRNA array analysis of plasma miRNA alterations in rats exposed to a high altitude hypoxic environment
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64. Roxadustat in treating anemia in dialysis patients (ROAD): protocol and rationale of a multicenter prospective observational cohort study
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65. Pyruvate Kinase Activity Regulates Cystine Starvation Induced Ferroptosis Through Malic Enzyme 1 in Pancreatic Cancer Cells
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66. Serpinb3 is Overexpressed in the Liver in Presence of Iron Overload
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68. Dynamics of Iron Homeostasis in Health and Disease: Molecular Mechanisms and Methods for Iron Determination
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69. Immunoadsorption for heart failure is associated with normalization of iron metabolism
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70. Iron deficiency induces maturation-dependent loss of pancreatic β-cells
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72. Hepcidin–Ferroportin Axis, Gut Microbiota, and Ferroptosis Across Chronic Liver Diseases: Mechanistic Integration of an Iron Dysregulation Triad
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73. The hypoxia-inflammation cycle as a key mechanism of smoldering inflammation and progression in multiple sclerosis
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75. Érythropoïèse et métabolisme du fer: interactions et applications biomédicales
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95. Regulation of iron metabolism during liver injury
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