Comorbidities of hidradenitis suppurativa (acne inversa)
Open accessAbstract
Comorbidities of hidradenitis suppurativa (acne inversa) were reviewed by extracting original and review publications included in MEDLINE, EMBASE and COCHRANE libraries using the terms "hidradenitis," "Verneuil" and "acne inversa." Follicular occlusion disorders, inflammatory bowel diseases, especially Crohn disease, spondylarthropathy, other hyperergic diseases, genetic keratin disorders associated with follicular occlusion and squamous cell carcinoma were the most common hidradenitis suppurativa comorbid diseases. A first classification of these major comorbidities and their possible genetic background reveals a list of chromosome loci and genes, which could be hidradenitis suppurativa candidates. Most of these diseases belong to the group of autoinflammatory disorders, where th17 cell cytokines seem to play a central role.
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- Authors
- Fimmel, S., & Zouboulis, C. C.
- Affiliations
- Stiftung Charité (DE)
- Städtisches Klinikum Dessau (DE)
- Venue
- Dermato-Endocrinology
- Publisher
- Informa UK Limited
- Published
- 2010-01
- Volume
- 2
- Issue
- 1
- Pages
- 9-16
- ISSN
- 1938-1972 (ISSN-L)
- 1938-1980
- PMC
- PMC3084959
- OpenAlex
- W2057540123
- Cited by
- 245
- References
- 160
- Citations by year
- 2026: 13 · 2025: 10 · 2024: 21 · 2023: 18 · 2022: 20 · 2021: 21 · 2020: 21 · 2019: 24 · 2018: 21 · 2017: 16 · 2016: 23 · 2015: 22 · 2014: 3 · 2013: 8 · 2012: 2
- FWCI
- 4.26
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- Dermato-Endocrinology (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Hidradenitis Suppurativa and Treatments
- Health Sciences › Medicine › Epidemiology › Autoimmune and Inflammatory Disorders
- Health Sciences › Medicine › Dermatology › Acne and Rosacea Treatments and Effects
- Keywords
- hidradenitis suppurativa, comorbidities, inflammatory bowel disease, Crohn's disease, spondyloarthritis, hyperkeratosis, squamous cell carcinoma, autoinflammatory disease, Th17 cytokines, genetic susceptibility, candidate genes
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