Cited by 245Hidradenitis Suppurativa and TreatmentsAutoimmune and Inflammatory DisordersAcne and Rosacea Treatments and Effects

Comorbidities of hidradenitis suppurativa (acne inversa)

Open access
Fimmel, Sabine, Zouboulis, Christos C.·2010·Dermato-Endocrinology

Abstract

Comorbidities of hidradenitis suppurativa (acne inversa) were reviewed by extracting original and review publications included in MEDLINE, EMBASE and COCHRANE libraries using the terms "hidradenitis," "Verneuil" and "acne inversa." Follicular occlusion disorders, inflammatory bowel diseases, especially Crohn disease, spondylarthropathy, other hyperergic diseases, genetic keratin disorders associated with follicular occlusion and squamous cell carcinoma were the most common hidradenitis suppurativa comorbid diseases. A first classification of these major comorbidities and their possible genetic background reveals a list of chromosome loci and genes, which could be hidradenitis suppurativa candidates. Most of these diseases belong to the group of autoinflammatory disorders, where th17 cell cytokines seem to play a central role.

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Crossref · 10.4161/derm.2.1.12490

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160 of 160 references verified0 citation errors · 0 not checkable

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Authors
Fimmel, S., & Zouboulis, C. C.
Affiliations
  • Stiftung Charité (DE)
  • Städtisches Klinikum Dessau (DE)
Venue
Dermato-Endocrinology
Published
2010-01
Volume
2
Issue
1
Pages
9-16
ISSN
  • 1938-1972 (ISSN-L)
  • 1938-1980
OpenAlex
W2057540123
Cited by
245
References
160
Citations by year
2026: 13 · 2025: 10 · 2024: 21 · 2023: 18 · 2022: 20 · 2021: 21 · 2020: 21 · 2019: 24 · 2018: 21 · 2017: 16 · 2016: 23 · 2015: 22 · 2014: 3 · 2013: 8 · 2012: 2
FWCI
4.26
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • Dermato-Endocrinology (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Dermatology › Hidradenitis Suppurativa and Treatments
  • Health Sciences › Medicine › Epidemiology › Autoimmune and Inflammatory Disorders
  • Health Sciences › Medicine › Dermatology › Acne and Rosacea Treatments and Effects
Keywords
hidradenitis suppurativa, comorbidities, inflammatory bowel disease, Crohn's disease, spondyloarthritis, hyperkeratosis, squamous cell carcinoma, autoinflammatory disease, Th17 cytokines, genetic susceptibility, candidate genes

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