Cited by 245Hidradenitis Suppurativa and TreatmentsAutoimmune and Inflammatory DisordersAcne and Rosacea Treatments and Effects

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Comorbidities of hidradenitis suppurativa (acne inversa)

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Fimmel, Sabine, Zouboulis, Christos C.·2010·Dermato-Endocrinology

DOI 10.4161/derm.2.1.12490PMC PMC3084959

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Abstract

Comorbidities of hidradenitis suppurativa (acne inversa) were reviewed by extracting original and review publications included in MEDLINE, EMBASE and COCHRANE libraries using the terms "hidradenitis," "Verneuil" and "acne inversa." Follicular occlusion disorders, inflammatory bowel diseases, especially Crohn disease, spondylarthropathy, other hyperergic diseases, genetic keratin disorders associated with follicular occlusion and squamous cell carcinoma were the most common hidradenitis suppurativa comorbid diseases. A first classification of these major comorbidities and their possible genetic background reveals a list of chromosome loci and genes, which could be hidradenitis suppurativa candidates. Most of these diseases belong to the group of autoinflammatory disorders, where th17 cell cytokines seem to play a central role.

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European S1 guideline for the treatment of hidradenitis suppurativa/acne inversa
Zouboulis, C. C., Desai, N., Emtestam, L., Hunger, R. E., Ioannides, D., Juhász, I., Lapins, J., Matusiak, Ł., Prens, E. P., Revuz, J. E., et al. (2015) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.12966 · Cited by 1,102
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Hidradenitis Suppurativa/Acne Inversa: Criteria for Diagnosis, Severity Assessment, Classification and Disease Evaluation
Zouboulis, C. C., del Mármol, V., Mrowietz, U., Prens, E. P., Tzellos, T., & Jemec, G. B. E. (2015) · Dermatology · doi:10.1159/000431175 · Cited by 376

See all 245

Authors: Fimmel, S., & Zouboulis, C. C.
Affiliations: Stiftung Charité (DE)
Städtisches Klinikum Dessau (DE)
ORCID: Zouboulis, Christos C.
Venue: Dermato-Endocrinology
Publisher: Informa UK Limited
Published: 2010-01
Volume: 2
Issue: 1
Pages: 9-16
ISSN: 1938-1972 (ISSN-L)
1938-1980
DOI: 10.4161/derm.2.1.12490
PMC: PMC3084959
OpenAlex: W2057540123
Cited by: 245
References: 160
Citations by year: 2026: 13 · 2025: 10 · 2024: 21 · 2023: 18 · 2022: 20 · 2021: 21 · 2020: 21 · 2019: 24 · 2018: 21 · 2017: 16 · 2016: 23 · 2015: 22 · 2014: 3 · 2013: 8 · 2012: 2
FWCI: 4.26
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc
Locations: Dermato-Endocrinology (publishedVersion, cc-by-nc)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Dermatology › Hidradenitis Suppurativa and Treatments
Health Sciences › Medicine › Dermatology › Autoimmune and Inflammatory Disorders
Health Sciences › Medicine › Dermatology › Acne and Rosacea Treatments and Effects
Keywords: hidradenitis suppurativa, comorbidities, inflammatory bowel disease, Crohn's disease, spondyloarthritis, hyperkeratosis, squamous cell carcinoma, autoinflammatory disease, Th17 cytokines, genetic susceptibility, candidate genes

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Comorbidities of hidradenitis suppurativa (acne inversa)

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