The DOI matches its Crossref record; 145 of the 145 references it cites were found in a registry or an index.
Advanced glycation end products: Key players in skin aging?
Open accessAbstract
Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed. In the last years advanced glycation end products (AGEs) have received particular attention in this context. AGEs are formed in high amounts in diabetes but also in the physiological organism during aging. They have been etiologically implicated in numerous diabetes- and age-related diseases. Strategies inhibiting AGE accumulation and signaling seem to possess a therapeutic potential in these pathologies. However, still little is known on the precise role of AGEs during skin aging. In this review the existing literature on AGEs and skin aging will be reviewed. In addition, existing and potential anti-AGE strategies that may be beneficial on skin aging will be discussed.
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Cited by
Role of advanced glycation end products in cellular signaling
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Oxidative Stress in Aging Human Skin
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Molecular pathways associated with oxidative stress in diabetes mellitus
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Metadata
- Authors
- Gkogkolou, P., & Böhm, M.
- Venue
- Dermato-Endocrinology
- Publisher
- Informa UK Limited
- Published
- 2012-07
- Volume
- 4
- Issue
- 3
- Pages
- 259-270
- ISSN
- 1938-1972 (ISSN-L)
- 1938-1980
- OpenAlex
- W2029388843
- Cited by
- 584
- References
- 145
- FWCI
- 7.00
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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