The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Heavy metals, islet function and diabetes development
Open accessAbstract
It has long been believed that heavy metals possess many adverse health effects. Uncontrolled industrialization has released heavy metal pollution in the world. Heavy metal pollutants damage organ functions and disrupt physiological homeostasis. Diabetes mellitus is growing in prevalence worldwide. Several studies have indicated that the deficiency and efficiency of some essential trace metals may play a role in the islet function and development of diabetes mellitus. Some toxic metals have also been shown to be elevated in biological samples of diabetes mellitus patients. In the present work, we review the important roles of heavy metals in islet function and diabetes development in which the in vitro, in vivo or human evidences are associated with exposure to zinc, arsenic, cadmium, mercury and nickel. Through this work, we summarize the evidence which suggests that some heavy metals may play an important role in diabetes mellitus as environmental risk factors.
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Cites
Hazards of heavy metal contamination
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Consumption of Fish and n-3 Fatty Acids and Risk of Incident Alzheimer Disease
Morris, M. C., Evans, D. A., Bienias, J. L., Tangney, C. C., Bennett, D. A., Wilson, R. S., Aggarwal, N., & Schneider, J. (2003) · Archives of Neurology · doi:10.1001/archneur.60.7.940 · Cited by 1,135
Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress
Rolo, A. P., & Palmeira, C. M. (2006) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2006.01.003 · Cited by 1,007
Chimienti, F., Devergnas, S., Pattou, F., Schuit, F., Garcia-Cuenca, R., Vandewalle, B., Kerr-Conte, J., Van Lommel, L., Grunwald, D., Favier, A., et al. (2006) · Journal of Cell Science · doi:10.1242/jcs.03164 · Cited by 349
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Cited by
EDC-2: the endocrine society's second scientific statement on endocrine-disrupting chemicals
Gore, A. C., Chappell, V. A., Fenton, S. E., Flaws, J. A., Nadal, A., Prins, G. S., Toppari, J., & Zoeller, R. T. (2015) · Endocrine Reviews · doi:10.1210/er.2015-1010 · Cited by 2,407
Metabolism disrupting chemicals and metabolic disorders
Heindel, J. J., Blumberg, B., Cave, M., Machtinger, R., Mantovani, A., Mendez, M. A., Nadal, A., Palanza, P., Panzica, G., Sargis, R., et al. (2017) · Reproductive Toxicology · doi:10.1016/j.reprotox.2016.10.001 · Cited by 1,101
Cadmium Toxicity and Treatment
Bernhoft, R. A. (2013) · The Scientific World Journal · doi:10.1155/2013/394652 · Cited by 628
Aluminium toxicosis: a review of toxic actions and effects
Igbokwe, I. O., Igwenagu, E., & Igbokwe, N. A. (2019) · Interdisciplinary Toxicology · doi:10.2478/intox-2019-0007 · Cited by 395
Hectors, T. L. M., Vanparys, C., van der Ven, K., Martens, G. A., Jorens, P. G., Van Gaal, L. F., Covaci, A., De Coen, W., & Blust, R. (2011) · Diabetologia · doi:10.1007/s00125-011-2109-5 · Cited by 277
Metadata
- Authors
- Chen, Y. W., Yang, C. Y., Huang, C. F., Hung, D. Z., Leung, Y. M., & Liu, S. H.
- Venue
- Islets
- Publisher
- Informa UK Limited
- Published
- 2009-11
- Volume
- 1
- Issue
- 3
- Pages
- 169-176
- ISSN
- 1938-2014 (ISSN-L)
- 1938-2022
- OpenAlex
- W2147723332
- Cited by
- 249
- References
- 9
- FWCI
- 2.91
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: Heavy metals, islet function and diabetes development. https://app.cochat.ai/papers/10.4161/isl.1.3.9262
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- Chen, Y. W., Yang, C. Y., Huang, C. F., Hung, D. Z., Leung, Y. M., & Liu, S. H. (2009). Heavy metals, islet function and diabetes development. Islets. https://doi.org/10.4161/isl.1.3.9262
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
