The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Role of non-classical MHC class I molecules in cancer immunosuppression
Open accessAbstract
Growing neoplasms employ various mechanisms to evade immunosurveillance. The expression of non-classical MHC class I molecules by both immune and malignant cells in the tumor microenvironment constitute of the strategies used by tumors to circumvent the cytotoxic activity of effector cells of the immune system. The overexpression of HLA-G, -E, and -F is a common finding across a variety of malignancies. However, while the presence of HLA-G and HLA-E has been recently correlated with poor clinical outcome, information on the clinicopathological significance of HLA-F is limited. In the present review, we summarize studies on non-classical MHC class I molecules with special emphasis on their role in the modulation of anticancer immune responses.
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Beyond the increasing complexity of the immunomodulatory HLA-G molecule
Carosella, E. D., Favier, B., Rouas-Freiss, N., Moreau, P., & LeMaoult, J. (2008) · Blood · doi:10.1182/blood-2007-12-127662 · Cited by 348
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Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition
Pereira, B. I., Devine, O. P., Vukmanovic-Stejic, M., Chambers, E. S., Subramanian, P., Patel, N., Virasami, A., Sebire, N. J., Kinsler, V., Valdovinos, A., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-10335-5 · Cited by 556
Cancer immunotherapy: Opportunities and challenges in the rapidly evolving clinical landscape
Emens, L. A., Ascierto, P. A., Darcy, P. K., Demaria, S., Eggermont, A. M. M., Redmond, W. L., Seliger, B., & Marincola, F. M. (2017) · European Journal of Cancer · doi:10.1016/j.ejca.2017.01.035 · Cited by 566
Immunotherapy in Lung Cancer: Current Landscape and Future Directions
Mamdani, H., Matosevic, S., Khalid, A. B., Durm, G., & Jalal, S. I. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.823618 · Cited by 359
Gao, S., Li, T., Guo, Y., Sun, C., Xianyu, B., & Xu, H. (2020) · Advanced Materials · doi:10.1002/adma.201907568 · Cited by 300
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer
Dubrot, J., Du, P. P., Lane-Reticker, S. K., Kessler, E. A., Muscato, A. J., Mehta, A., Freeman, S. S., Allen, P. M., Olander, K. E., Ockerman, K. M., et al. (2022) · Nature Immunology · doi:10.1038/s41590-022-01315-x · Cited by 218
Metadata
- Authors
- Kochan, G., Escors, D., Breckpot, K., & Guerrero-Setas, D.
- Venue
- OncoImmunology
- Publisher
- Informa UK Limited
- Published
- 2013-11
- Volume
- 2
- Issue
- 11
- Pages
- e26491
- ISSN
- 2162-4011 (ISSN-L)
- 2162-402X
- OpenAlex
- W1990757073
- Cited by
- 159
- References
- 1
- FWCI
- 5.51
- Type
- journal article
- Language
- en
- Open access
- gold
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- Kochan, G., Escors, D., Breckpot, K., & Guerrero-Setas, D. (2013). Role of non-classical MHC class I molecules in cancer immunosuppression. OncoImmunology. https://doi.org/10.4161/onci.26491
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