The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Biomarkers of endothelial activation/dysfunction in infectious diseases
Open accessAbstract
Endothelial dysfunction contributes to the pathogenesis of a variety of potentially serious infectious diseases and syndromes, including sepsis and septic shock, hemolytic-uremic syndrome, severe malaria, and dengue hemorrhagic fever. Because endothelial activation often precedes overt endothelial dysfunction, biomarkers of the activated endothelium in serum and/or plasma may be detectable before classically recognized markers of disease, and therefore, may be clinically useful as biomarkers of disease severity or prognosis in systemic infectious diseases. In this review, the current status of mediators of endothelial cell function (angiopoietins-1 and -2), components of the coagulation pathway (von Willebrand Factor, ADAMTS13, and thrombomodulin), soluble cell-surface adhesion molecules (soluble E-selectin, sICAM-1, and sVCAM-1), and regulators of vascular tone and permeability (VEGF and sFlt-1) as biomarkers in severe infectious diseases is discussed in the context of sepsis, E. coli O157:H7 infection, malaria, and dengue virus infection.
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Cites
The biology of VEGF and its receptors
Ferrara, N., Gerber, H.-P., & LeCouter, J. (2003) · Nature Medicine · doi:10.1038/nm0603-669 · Cited by 9,591
Excess Circulating Angiopoietin-2 May Contribute to Pulmonary Vascular Leak in Sepsis in Humans
Parikh, S. M., Mammoto, T., Schultz, A., Yuan, H.-T., Christiani, D., Karumanchi, S. A., & Sukhatme, V. P. (2006) · PLoS Medicine · doi:10.1371/journal.pmed.0030046 · Cited by 527
Conroy, A. L., Liles, W. C., Molyneux, M. E., Rogerson, S. J., & Kain, K. C. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028540 · Cited by 46
Self-citation
Cited by
Gust, J., Hay, K. A., Hanafi, L.-A., Li, D., Myerson, D., Gonzalez-Cuyar, L. F., Yeung, C., Liles, W. C., Wurfel, M., Lopez, J. A., et al. (2017) · Cancer Discovery · doi:10.1158/2159-8290.cd-17-0698 · Cited by 1,400
Self-citationHay, K. A., Hanafi, L.-A., Li, D., Gust, J., Liles, W. C., Wurfel, M. M., López, J. A., Chen, J., Chung, D., Harju-Baker, S., et al. (2017) · Blood · doi:10.1182/blood-2017-06-793141 · Cited by 1,156
Self-citationEndothelial barrier dysfunction in septic shock
Opal, S. M., & van der Poll, T. (2015) · Journal of Internal Medicine · doi:10.1111/joim.12331 · Cited by 353
Markers and Biomarkers of Endothelium: When Something Is Rotten in the State
Goncharov, N. V., Nadeev, A. D., Jenkins, R. O., & Avdonin, P. V. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/9759735 · Cited by 190
Endothelial Permeability and Hemostasis in Septic Shock
Hou, P. C., Filbin, M. R., Wang, H., Ngo, L., Huang, D. T., Aird, W. C., Yealy, D. M., Angus, D. C., Kellum, J. A., & Shapiro, N. I. (2017) · Chest · doi:10.1016/j.chest.2017.01.010 · Cited by 97
Metadata
- Authors
- Page, A. V., & Liles, W. C.
- Venue
- Virulence
- Publisher
- Informa UK Limited
- Published
- 2013-08-15
- Volume
- 4
- Issue
- 6
- Pages
- 507-516
- ISSN
- 2150-5594 (ISSN-L)
- 2150-5608
- OpenAlex
- W2022387905
- Cited by
- 270
- References
- 3
- FWCI
- 15.35
- Type
- journal article
- Language
- en
- Open access
- gold
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