Animal models of sepsis

Fink, Mitchell P·2014·Virulence
DOI 10.4161/viru.26083

Cited by (389)

Items 101–200 of 389

  1. Inhibitory effect of porphyran on lipopolysaccharide-induced activation of human immune cells
    Yuhua Wang, Juyoung Hwang, Dhananjay Yadav, Tatsuya Oda, Peter Chang-Whan Lee, Jun‐O Jin · 2019 · Carbohydrate Polymers
  2. Pre-eclamptic Fetal Programming Alters Neuroinflammatory and Cardiovascular Consequences of Endotoxemia in Sex-Specific Manners
    Salwa Aburageh Abuiessa, Abdalla M. Wedn, Sahar M. El‐Gowilly, Mai M. Helmy, Mahmoud M. El‐Mas · 2020 · Journal of Pharmacology and Experimental Therapeutics
  3. Thioredoxin‐Interacting Protein (TXNIP) Knockdown Protects against Sepsis‐Induced Brain Injury and Cognitive Decline in Mice by Suppressing Oxidative Stress and Neuroinflammation
    Yu Zhang, Chengjun Xing, Xiao Liu, Ya-Hong Li, Jing Jia, Jianguo Feng, Cheng‐Jie Yang, Ye Chen, Jun F. Zhou · 2022 · Oxidative Medicine and Cellular Longevity
  4. Evaluation of 2 Rat Models for Sepsis Developed by Improved Cecal Ligation/Puncture or Feces Intraperitoneal-Injection
    Hui Fang, Chenchen Gong, Jianyu Fu, Xu Liu, Hongying Bi, Yumei Cheng, Yiyuan Liu, Yan Tang, Difen Wang · 2020 · Medical Science Monitor
  5. Sepsis and the evolution of human increased sensitivity to lipopolysaccharide
    Jessica F. Brinkworth, Negin Valizadegan · 2021 · Evolutionary Anthropology Issues News and Reviews
  6. Emerging therapeutic targets for sepsis
    Elizabeth W. Tindal, Brandon E. Armstead, Sean F. Monaghan, Daithi S. Heffernan, Alfred Ayala · 2021 · Expert Opinion on Therapeutic Targets
  7. Cigarette smoke exposure worsens acute lung injury in antibiotic-treated bacterial pneumonia in mice
    Jeffrey E. Gotts, Lauren F. Chun, Jason Anthony Abbott, Xiaohui Fang, Naoki Takasaka, Stephen L. Nishimura, Matthew L. Springer, Suzaynn F. Schick, Carolyn S. Calfee, Michael A. Matthay · 2018 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  8. Kynurenine Pathway—An Underestimated Factor Modulating Innate Immunity in Sepsis-Induced Acute Kidney Injury?
    Anna Krupa, Mikolaj M. Krupa, Krystyna Pawlak · 2022 · Cells
  9. An update on endotoxin neutralization strategies in Gram-negative bacterial infections
    Klaus Brandenburg, Andra Beate Schromm, Günther Weindl, Lena Heinbockel, Wilmar Correa, Karl Mauss, Guillermo Martínez de Tejada, Patrick Garidel · 2020 · Expert Review of Anti-infective Therapy
  10. Cytoprotective effect of aquaporin 1 against lipopolysaccharide‑induced apoptosis and inflammation of renal epithelial HK‑2 cells
    Yiduo Wang, Wenzheng Zhang, Guangzhe Yu, Qian Liu, Yingyu Jin · 2018 · Experimental and Therapeutic Medicine
  11. Protective effects of exogenous NaHS against sepsis-induced myocardial mitochondrial injury by enhancing the PGC-1α/NRF2 pathway and mitochondrial biosynthesis in mice.
    Dongshi Liang, Airong Huang, Yimei Jin, Miaomiao Lin, Xiaojiao Xia, Xiaoli Chen, Airong Huang · 2018 · Europe PMC (PubMed Central)
  12. Caspase-4 and -5 Biology in the Pathogenesis of Inflammatory Bowel Disease
    Aoife P. Smith, Emma M. Creagh · 2022 · Frontiers in Pharmacology
  13. Sevoflurane attenuates systemic inflammation compared with propofol, but does not modulate neuro-inflammation
    Beatrice Beck‐Schimmer, Lukas Baumann, Tanja Restin, Philipp Eugster, Melanie Hasler, Christa Booy, Martin Schläpfer · 2017 · European Journal of Anaesthesiology
  14. Selection of Models: Evolution and the Choice of Species for Translational Research
    Jessica A. Bolker · 2019 · Brain Behavior and Evolution
  15. Prevention of lipopolysaccharide-induced CD11b+ immune cell infiltration in the kidney: role of AT2 receptors
    Sanket Niranjanbhai Patel, Isha S. Dhande, Elizabeth A. Gray, Quaisar Ali, Tahir Hussain · 2019 · Bioscience Reports
  16. Sex-differences in LPS-induced neonatal lung injury
    Leanna Nguyen, Odalis Castro, Robyn K. De Dios, Jeryl Sandoval, Sarah McKenna, Clyde J. Wright · 2019 · Scientific Reports
  17. Cecal Slurry Injection in Neonatal and Adult Mice
    Jaimar C. Rincon, Philip Alexander Efron, Lyle L. Moldawer, Shawn D. Larson · 2021 · Methods in molecular biology
  18. Identification of Clinical Phenotypes in Septic Patients Presenting With Hypotension or Elevated Lactate
    Zachary Aldewereld, Li Ang Zhang, Alisa Urbano, Robert S. Parker, David Swigon A, Ipsita Banerjee, Hernando Gómez, Gilles Clermont · 2022 · Frontiers in Medicine
  19. Loss of ZBED6 Protects Against Sepsis‐Induced Muscle Atrophy by Upregulating DOCK3‐Mediated RAC1/PI3K/AKT Signaling Pathway in Pigs
    Huan Liu, Dengke Pan, Pu Li, Dandan Wang, Bo Xia, Ruixin Zhang, Jun Feng Lu, Xiangyang Xing, Jiaxiang Du, Xiao Zhang et al. · 2023 · Advanced Science
  20. Translational Sepsis Research: Spanning the Divide
    Anthony Lewis, Janet S. Lee, Matthew Randall Rosengart · 2018 · Critical Care Medicine
  21. Animal-Free Human Whole Blood Sepsis Model to Study Changes in Innate Immunity
    David Alexander Christian Messerer, Laura Vidoni, Maike Erber, Alexander Elias Paul Stratmann, Jonas Martin Bauer, Christian Braun, Stefan Hug, Anna Adler, Kristina Nilsson Ekdahl, Bo Nilsson et al. · 2020 · Frontiers in Immunology
  22. High concentration of hydrogen gas alleviates Lipopolysaccharide-induced lung injury via activating Nrf2 signaling pathway in mice
    Ruiqiang Sun, Nan Zhao, Yuzun Wang, Yanchao Su, Jiayan Zhang, Yaoqi Wang, Yonghao Yu, Guolin Wang, Zhen Wang, Keliang Xie · 2021 · International Immunopharmacology
  23. Transcriptional Response in a Sepsis Mouse Model Reflects Transcriptional Response in Sepsis Patients
    Florian Rosier, Nicolas Fernandez, Magali Torres, Béatrice Loriod, Pascal Rihet, Lydie C. Pradel · 2022 · International Journal of Molecular Sciences
  24. The Trend of β3-Adrenergic Receptor in the Development of Septic Myocardial Depression: A Lipopolysaccharide-Induced Rat Septic Shock Model
    Ni Yang, Xiao-Lu  Shi, Binglun Zhang, Jian  Rong, Tie‐Ning Zhang, Wei Xu, Chunfeng Liu · 2018 · Cardiology
  25. Targeting of reactive isolevuglandins in mitochondrial dysfunction and inflammation
    Vladimir Mayorov, Peter Uchakin, Venkataraman Amarnath, Alexander V. Panov, Christy C. Bridges, Roman V. Uzhachenko, Bill Zackert, Christy S. Moore, Sean S. Davies, Anna Dikalova et al. · 2019 · Redox Biology
  26. Endothelial ADAM10 utilization defines a molecular pathway of vascular injury in mice with bacterial sepsis
    Danielle N. Alfano, Mark J. Miller, Juliane Bubeck Wardenburg · 2023 · Journal of Clinical Investigation
  27. Choosing the right animal model for osteomyelitis research: Considerations and challenges
    Shen Huang, Jing Wen, Yiqing Zhang, Xiaochun Bai, Zhong‐Kai Cui · 2023 · Journal of Orthopaedic Translation
  28. Molecular profiling of sepsis in mice using Fourier Transform Infrared Microspectroscopy
    Rekha Gautam, Mukta Deobagkar‐Lele, Shamik Majumdar, Bhagawat C. Subramanian, Emmanuel Stephen Victor, Syed Moiz Ahmed, Nitin Wadhwa, Taru Verma, Srividya Kumar, Nagalingam Ravi Sundaresan et al. · 2015 · Journal of Biophotonics
  29. Characterization of Fecal Peritonitis–Induced Sepsis in a Porcine Model
    Inwon Park, Jae Hyuk Lee, Dong‐Hyun Jang, Doyun Kim, Hyunglan Chang, Hyuksool Kwon, Seonghye Kim, Taek Soo Kim, You Hwan Jo · 2019 · Journal of Surgical Research
  30. Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3
    Zhe Cheng, Dingyi Lv, Minghao Luo, Ruiyu Wang, Yongzheng Guo, Xiyang Yang, Longxiang Huang, Xingbing Li, Chang Li, Fei‐Fei Shang et al. · 2021 · European Journal of Pharmacology
  31. Coupling killing to neutralization: combined therapy with ceftriaxone/Pep19-2.5 counteracts sepsis in rabbits
    Sergio Bárcena‐Varela, Guillermo Martínez de Tejada, Lukas Märtin, Tobias Schuerholz, Ana Gloria Gil-Royo, Satoshi Fukuoka, Torsten Goldmann, Daniel Droemann, Wilmar Correa, Thomas Gutsmann et al. · 2017 · Experimental & Molecular Medicine
  32. ClearColi BL21(DE3)-based expression of Zika virus antigens illustrates a rapid method of antibody production against emerging pathogens
    Wildriss Viranaïcken, Brice Nativel, Pascale Krejbich Trotot, Wissal Harrabi, Sandra Bos, Chaker El Kalamouni, Marjolaine Roche, Gilles Gadéa, Philippe Desprès · 2017 · Biochimie
  33. Whole-organism phenotypic screening for anti-infectives promoting host health
    Anne E. Clatworthy, Keith P. Romano, Deborah Tan Hung · 2018 · Nature Chemical Biology
  34. Mitochondrial Function in the Kidney and Heart, but Not the Brain, is Mainly Altered in an Experimental Model of Endotoxaemia
    Marina Makrecka‐Kuka, Stanislava Korzh, Kārlis Vilks, Reinis Vilšķe̅rsts, Helena Cirule, Maija Dambrova, Edgars Liepinsh · 2019 · Shock
  35. Interactive and independent effects of early lipopolysaccharide and hyperoxia exposure on developing murine lungs
    Amrit Kumar Shrestha, Renuka Menon, Ahmed El‐Saie, Roberto J. Barrios, Corey L. Reynolds, Binoy Shivanna · 2020 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  36. Single versus combined immunoregulatory approach using PD-1 and CTLA-4 modulators in controlling sepsis
    Courtney P. Rudick, David L. Cornell, Devendra K. Agrawal · 2017 · Expert Review of Clinical Immunology
  37. TSLP Exacerbates Septic Inflammation via Murine Double Minute 2 (MDM2) Signaling Pathway
    Na‐Ra Han, Phil‐Dong Moon, Hyung‐Min Kim, Hyun‐Ja Jeong · 2019 · Journal of Clinical Medicine
  38. Comparison of response to LPS-induced sepsis in three DBA/2 stocks derived from different sources
    Ji Won Park, Su Jin Lee, Ji Eun Kim, Mi Ju Kang, Su Ji Bae, Yun Ju Choi, Jeong Eun Gong, Kil‐Soo Kim, Young‐Suk Jung, Joon‐Yong Cho et al. · 2021 · Laboratory Animal Research
  39. ABT-263 enhanced bacterial phagocytosis of macrophages in aged mouse through Beclin-1-dependent autophagy
    Yu Zhang, Li-hua Tang, Jia Q. Lu, Liming Xu, Baoli Cheng, Junyu Xiong · 2021 · BMC Geriatrics
  40. Retinoic Acid-Induced Regulation of Inflammatory Pathways Is a Potential Sepsis Treatment
    Hallie H. Dolin, Justin H. Franco, Xiaohuan Chen, Zhixing K. Pan · 2023 · Infection and Immunity
  41. Pharmacological depletion of microglia alleviates neuronal and vascular damage in the diabetic CX3CR1-WT retina but not in CX3CR1-KO or hCX3CR1I249/M280-expressing retina
    Kaira A. Church, Derek Rodriguez, Andrew S. Mendiola, Difernando Vanegas, Irene L. Gutiérrez, Ian M. Tamayo, Abdul Amadu, Priscila Velazquez, Sandra M. Cardona, Stefka Gyoneva et al. · 2023 · Frontiers in Immunology
  42. Therapeutic Targets in Sepsis
    Eric J. Seeley, Gordon R. Bernard · 2016 · Clinics in Chest Medicine
  43. Development and Characterization of an Endotoxemia Model in Zebra Fish
    Alan Yi-Hui Hsu, Theodore Gurol, Tiago J. P. Sobreira, Sheng Zhang, Natalie Moore, Chufan Cai, Zhong‐Yin Zhang, Qing Deng · 2018 · Frontiers in Immunology
  44. Drug Repositioning to Alleviate Systemic Inflammatory Response Syndrome Caused by Gram‐Negative Bacterial Outer Membrane Vesicles
    Ji Hyun Kim, Jaewook Lee, Kyong‐Su Park, Sung‐Wook Hong, Yong Song Gho · 2018 · Advanced Healthcare Materials
  45. Sepsis-associated endothelial glycocalyx damage: a review of animal models, clinical evidence, and molecular mechanisms
    Junhui Zhan, Juan Wei, Yujian Liu, Peng-Xiang Wang, Xiaoyan Zhu · 2025 · International Journal of Biological Macromolecules
  46. Circumferential strain rate to detect lipopolysaccharide-induced cardiac dysfunction: a speckle tracking echocardiography study
    Ming Chu, Lijun Qian, Menglin Zhu, Jing Yao, Di Xu, Minglong Chen · 2019 · Quantitative Imaging in Medicine and Surgery
  47. Cecropin-like antimicrobial peptide protects mice from lethal E.coli infection
    Anishma Shrestha, Deepesh Duwadi, James A. Jukosky, Steven Fiering · 2019 · PLoS ONE
  48. Variability of Mitochondrial Respiration in Relation to Sepsis-Induced Multiple Organ Dysfunction
    Michaela Kohoutová, Jiri Dejmek, Zdeněk Tůma, Jitka Kuncová · 2018 · Physiological Research
  49. An Adrenalectomy Mouse Model Reflecting Clinical Features for Chronic Fatigue Syndrome
    Jin-Seok Lee, Yoo-Jin Jeon, Samuel-Young Park, Chang‐Gue Son · 2020 · Biomolecules
  50. Models of sepsis-induced acute kidney injury
    Liang Dong, Yi-Ling Xie, Ren-Tao Zhang, Hu Q · 2024 · Life Sciences
  51. Modelling physical resilience in ageing mice
    Markus Schosserer, Gareth T. Banks, Soner Doğan, Peter Dungel, Adelaide Maria Afonso Fernandes, Darja Marolt, Ander Matheu, Marcin Filip Osuchowski, Paul K Potter, Coral Sanfeliu et al. · 2018 · Mechanisms of Ageing and Development
  52. Neulasta regimen for the hematopoietic acute radiation syndrome: effects beyond neutrophil recovery
    Legesse, Betre, Kaur, Amandeep, Kenchegowda, Doreswamy, Hritzo, Bernadette, Culp, William E., Moroni, Maria · 2019 · International Journal of Radiation Oncology*Biology*Physics
  53. Evaluation of Pseudomonas aeruginosa pathogenesis and therapeutics in military‐relevant animal infection models
    Alexander G. Bobrov, Derese Getnet, Brett E. Swierczewski, Anna C. Jacobs, Maria Medina‐Rojas, Stuart D. Tyner, Chase Watters, Vlado Antonic · 2021 · Apmis
  54. P2X7 receptor antagonist A-438079 alleviates oxidative stress of lung in LPS-induced septic rats
    Seçkin Özkanlar, Nergis Ulaş, Özgür Kaynar, Emine Satıcı · 2023 · Purinergic Signalling
  55. The small heat shock protein HSPB1 protects mice from sepsis
    Elise R. Breed, Carolyn A. Hilliard, Benyam P. Yoseph, Rohit Mittal, Zhe Liang, Ching‐Wen Chen, Eileen M. Burd, Luke Packard Brewster, Laura Hansen, Rudolph L. Gleason et al. · 2018 · Scientific Reports
  56. TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria
    Birgitta Ehrnström, June Frengen Kojen, Miriam S. Giambelluca, Liv Ryan, Siv Helen Moen, Zhenyi Hu, Hang Hubert Yin, Tom Eirik Mollnes, Jan Kristian Damås, Terje Espevik et al. · 2020 · Journal of Leukocyte Biology
  57. Post-translational modifications in sepsis-induced organ dysfunction: mechanisms and implications
    Lin Song, Wei Jiang, Hua Lin, Jiangquan Yu, Ke Liu, Ruiqiang Zheng · 2024 · Frontiers in Immunology
  58. Could Biomarkers Direct Therapy for the Septic Patient?
    Clark R. Sims, Trung C. Nguyen, Philip R. Mayeux · 2016 · Journal of Pharmacology and Experimental Therapeutics
  59. Cytokine-Induced JAK2-STAT3 Activates Tissue Regeneration under Systemic or Local Inflammation
    Young Kyu Kim, Ju Young Lee, Han Na Suh · 2022 · International Journal of Molecular Sciences
  60. Pulsed Electromagnetic Field (PEMF) Treatment Reduces Lipopolysaccharide-Induced Septic Shock in Mice
    Chang-Gun Lee, Chanoh Park, Soonjae Hwang, Ju-Eun Hong, Minjeong Jo, Minseob Eom, Yong‐Heum Lee, Ki‐Jong Rhee · 2022 · International Journal of Molecular Sciences
  61. Protection Against Lipopolysaccharide-Induced Immunosuppression by IgG and IgM
    Christiana Kyvelidou, Dimitris Sotiriou, Ioanna Zerva, Irene Athanassakis · 2017 · Shock
  62. Amyloid Beta Pathology Exacerbates Weight Loss and Brain Cytokine Responses following Low-Dose Lipopolysaccharide in Aged Female Tg2576 Mice
    Knopp, Rachel C., Baumann, Kristen K., Wilson, Miranda L., Banks, William A., Erickson, Michelle A. · 2022 · International Journal of Molecular Sciences
  63. The effects of bacterial endotoxin (LPS) on cardiac function in a medicinal blow fly (Phaenicia sericata) and a fruit fly (Drosophila melanogaster)
    Ogechi Anyagaligbo, Jate Bernard, Abigail Greenhalgh, Robin Lewis Cooper · 2018 · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology
  64. Using the Cecal Ligation and Puncture Model of Sepsis to Induce Rats to Multiple Organ Dysfunction
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  65. Cardiomyocyte-specific disruption of soluble epoxide hydrolase limits inflammation to preserve cardiac function
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  66. Astragaloside IV alleviates sepsis-induced muscle atrophy by inhibiting the TGF-β1/Smad signaling pathway
    Hongkai Dai, Yingfang Zheng, Renyu Chen, Yurou Wang, Yanxia Zhong, Chenchen Zhou, Chengye Zhan, Jinlong Luo · 2022 · International Immunopharmacology
  67. Intestine-Specific Deletion of Microsomal Triglyceride Transfer Protein Increases Mortality in Aged Mice
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  68. Animal models of kidney inflammation in translational medicine
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  69. The ten barriers for translation of animal data on AKI to the clinical setting
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  70. Defibrinogenation Ameliorates Retinal Microgliosis and Inflammation in A CX3CR1-Independent Manner
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  71. Small animal models of thermal injury
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  72. Analysis of target organs of Houttuynia cordata: A study on the anti-inflammatory effect of upper respiratory system
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  73. Severe gut mucosal injury induces profound systemic inflammation and spleen-associated lymphoid organ response
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  74. Pericytes Enrich the Basement Membrane and Reduce Neutrophil Transmigration in an In Vitro Model of Peripheral Inflammation at the Blood–Brain Barrier
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  75. Early hemorheological changes in a porcine model of intravenously given E. coli induced fulminant sepsis
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  78. An ex vivo porcine spleen perfusion as a model of bacterial sepsis
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  84. The role of speckle tracking echocardiography in assessment of lipopolysaccharide-induced myocardial dysfunction in mice.
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  85. New Approaches to Identify Sepsis Biomarkers: The Importance of Model and Sample Source for Mass Spectrometry
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  91. The Effects of Bacterial Lipopolysaccharide (LPS) on Turkey Poults: Assessment of Biochemical Parameters and Histopathological Changes
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  92. Beneficial Effects of O-GlcNAc Stimulation in a Young Rat Model of Sepsis: Beyond Modulation of Gene Expression
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  93. Fibroblast Growth Factor 19 Improves LPS‐Induced Lipid Disorder and Organ Injury by Regulating Metabolomic Characteristics in Mice
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  94. Sepsis induced by cecal ligation and perforation (CLP) alters nucleotidase activities in platelets of rats
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  95. Cereblon deficiency confers resistance against polymicrobial sepsis by the activation of AMP activated protein kinase and heme-oxygenase-1
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  96. Comparison of Pulmonary and Extrapulmonary Models of Sepsis-Associated Acute Lung Injury
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  97. Retinal response to systemic inflammation differs between sexes and neurons
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  98. Effects of ozone exposure on lung injury, inflammation, and oxidative stress in a murine model of nonpneumonic endotoxemia
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  99. Charting new frontiers in nanoparticle immunotoxicity: A perspective on current, emerging, and future approaches
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  100. Recombinant human thrombomodulin attenuated sepsis severity in a non-surgical preterm mouse model
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