Animal models of sepsis

Cited by (389)

Items 301–389 of 389

1. New horizon in the treatment of sepsis: a systematic review of alternative medicine
   Sarah Mousavi, Alireza Ghannadi, Mohsen Meidani · 2016 · Journal of Complementary and Integrative Medicine
2. Immunomodulation by Vasoactive Intestinal Polypeptide (VIP)
   Kirsten M. Hooper, Weimin Kong, Doina Ganea · 2016 · Springer eBooks
3. Animal Models in Surgical Research
   Morgan L. Hennessy, Allan M. Goldstein · 2019 · Success in academic surgery
4. MОDELING OF DIFFUSE PURULENT PERITONITIS
   Елена Чепурных, Шурыгина Ирина Александровна, Т. В. Фадеева, E.G. Grigorev · 2020 · Современные проблемы науки и образования
5. Increased circulating peroxiredoxin-4 in sepsis model rats involves secretion from hepatocytes and is mitigated by GYY4137
   Kana Unuma, Ayaka Yoshikawa, Toshihiko Aki, Koichi Uemura · 2019 · Journal of Toxicologic Pathology
6. Rat Models of Infectious Disease
   Jolaine M. Wilson, Paul E. Makidon, Ingrid L. Bergin · 2019 · Elsevier eBooks
7. Role of Myeloid Cell-Specific Adenylyl Cyclase Type 7 in Lipopolysaccharide- and Alcohol-Induced Immune Responses
   Yawen Hu, Sonika Patial, Yogesh Saini, Masami Yoshimura · 2024 · International Journal of Molecular Sciences
8. Sepsis-related myocardial injury: the role of bacterial pathogens and toxins—a scoping review protocol
   Samantha Lörstad, Jacob Widaeus, Patrik Gille-Johnson, Jonas Persson · 2025 · BMJ Open
9. Protection of mice against septic shock induced by lethal intraperitoneal dose of LPS by a recombinant Fasciola hepatica fatty acid binding protein
   Albersy Armina-Rodríguez, Stephanie M Dorta-Estremera, Loyda B. Méndez, Ana Margarita Espino · 2026 · Microbiology Spectrum
10. CIGB-258, a Potential Novel Approach to Treat Sepsis-like Hyperinflammation, Reduces Gastrointestinal Hemorrhage in Zebrafish Exposed to Carboxymethyllysine and Ethanol
    Kyung‐Hyun Cho, Yunki Lee, Sang Hyuk Lee, Ashutosh Bahuguna, María del Carmen Domínguez-Horta, Gillian Martínez‐Donato · 2026 · Pharmaceuticals
11. In Vivo Investigation of Filovirus Glycoprotein-Mediated Infection in a BSL2 Setting
    Paige T. Richards, José A. Aguilar-Briseño, Bethany A. Brunton, Wendy J. Maury · 2024 · Methods in molecular biology
12. Inactivation of PI3K-C2α deregulates cell death pathways and sensitizes to endotoxic shock
    York Posor, Sarah E. Conduit, Wayne P Pearce, Daniele Morelli, Georgia Constantinou, Maria A. Whitehead, Neil James Sebire, Cheryl L. Scudamore, Nieves Peltzer, Henning Walczak et al. · 2025 · Proceedings of the National Academy of Sciences
13. Effects of Ghrelin on Inflammation and Oxidative Stress Parameters in Sepsis-induced Liver Tissue of Rat
    Gulten Ates, Elif Özkök, Hatice Yorulmaz, İrfan Aydın, Şule Tamer · 2016 · Asian Journal of Animal and Veterinary Advances
14. The antisecretory peptide AF-16 may modulate tissue edema but not inflammation in experimental peritonitis induced sepsis
    Annelie Barrueta Tenhunen, Jaap van der Heijden, Ivan Blokhin, Fabrizia Massaro, Hans Arne Hansson, Ricardo E. Feinstein, Anders Larsson, Anders Larsson, Jyrki J. Tenhunen · 2020 · PLoS ONE
15. Intestinal edema induced by LPS-induced endotoxemia is associated with an inflammasome adaptor ASC
    Toshihiro Yamamoto, Mie Kurata, Naoe Kaneko, Junya Masumoto · 2023 · PLoS ONE
16. Acute and Chronic Kidney Disease Worsen Outcomes in Experimental Sepsis
    Deana F. Floyd, James F. Colbert, Frances Xiuyan Feng, Seth B. Furgeson, John R. Montford · 2024 · Kidney360
17. Elevated level of extracellular vimentin is associated with an increased fibrin formation potential in sepsis: ex vivo swine study
    Marina Martinez-Vargas, Arun Saini, Subhashree Pradhan, Luis Gardea, Barbara Stoll, Inka C. Didelija, K. Vinod Vijayan, Trung Cong Nguyen, Miguel A. Crúz · 2024 · Intensive Care Medicine Experimental
18. Nebivolol Exerts Hepatoprotective Activity During CLP-Induced Sepsis by Modulating Oxidative Stress, Liver Regeneration, and AKT/MAPK Pathways in Rats
    Rahma Tharwat Sabra, Amany Abdlrehim Bekhit, Nourhan Tharwat Sabra, Nadia Ahmed Abd El-Moeze, Moustafa Fathy · 2024 · Stresses
19. Cannabinoids in preclinical research of sepsis: a scoping review
    Carolina Henkes Inamassu, Regina Sordi, Camila Marchioni · 2025 · Inflammation Research
20. Utility of Animal Models of Pneumonia and Sepsis
    Hiroki Taenaka, Mazharul Maishan, Ruriko Watanabe, Michael A. Matthay · 2025 · Clinics in Chest Medicine
21. Assessment of methylene blue and NAD on LPS-induced acute brain injury: effects on neuroinflammation, oxidative stress, and blood–brain barrier integrity in a rat endotoxemia model
    Songül Doğanay, Hilal Üstündağ, Elif Erbaş, Sevinç Yanar, Serhat Hayme, Nezahat Kurt · 2026 · Naunyn-Schmiedeberg s Archives of Pharmacology
22. Cell death mechanisms in sepsis-associated adaptive immune dysfunction
    Xiaofang Li, Weiwei Qian, Na Cao, Yarong He · 2026 · Journal of Critical Care
23. Central infusion of prostaglandin E2 reveals a unified representation of sickness in the mouse insular cortex
    Gretel B. Kamm, Juan Carlos Boffi, Muad Y Abd El Hay, Domitille Rajot, Ana Cukić, Martha Nari Havenith, Marieke Louise Schölvinck, Nicolas Renier, Hiroki Asari, Robert Prevedel · 2026 · Current Biology
24. A Modified Rat Model of Cecal Ligation and Puncture for Adjusting the Severity of Septic Acute Kidney Injury
    Ning Zhao, Jiaquan Chen, Wei Peng, Rong Jiang, Zhiyong Peng, Fen Liu · 2021 · Journal of Translational Critical Care Medicine
25. Inflammasomes in sepsis
    Laura Hurtado‐Navarro, Carlos García-Palenciano, Pablo Pelegrı́n · 2022 · Elsevier eBooks
26. In Vivo Simulation of the Purulent Peritonitis
    В. А. Лазаренко, В. А. Липатов, Д. А. Северинов, V. P. Gavriliouk, Бобровская Елена Анатольевна · 2023 · Innovative medicine of Kuban
27. Plasma lipopolysaccharide elevations in cattle associated with early‐stage infection by Fasciola hepatica
    D Marendy, L Gábor, SD George, Anthony J Parker, Emma Doyle · 2023 · Australian Veterinary Journal
28. High mobility group box protein 1 neutralization therapy in ovine bacteremia: Lessons learned from an ovine septic shock model incorporating intensive care support
    Natalie E. Stevens, Coralie H. Nash, Cara K. Fraser, Tim R. Kuchel, Matthew J. Maiden, Marianne J. Chapman, Kerrilyn R. Diener, John D. Hayball · 2019 · Experimental and Therapeutic Medicine
29. Animal Models of Coagulopathy
    Daniel T. Lammers, Matthew Jeffrey Martin · 2020 · Springer eBooks
30. The effects of Gram-positive and Gram-negative bacterial toxins (LTA & LPS) on cardiac function in Drosophila melanogaster larvae.
    Kaitlyn E. Brock, Elizabeth R. Elliott, Maya O. Abul-Khoudoud, R. Cooper · 2023 · Journal of insect physiology
31. Role of microbiome in development of systemic inflammatory response syndrome and sepsis (review)
    Tatiana I. Khomyakova, Yu.N. Khomyakov, Olga V. Makarova · 2023 · Epidemiology and Infectious Diseases
32. Development of a translational animal model of sepsis
    Nathaniel Edward Hayward · 2013 · Scholarship@Western (Western University)
33. The recognition of LpxC inhibitors as potential antibiotics could revolutionise the management of sepsis in veterinary patients if their unknown biological properties are widely evaluated in suitable animal models
    Saul Chemonges · 2014 · International Journal of Veterinary Science and Medicine
34. Memory deficits in males and females long after subchronic immune challenge
    Daria Tchessalova, Natalie Celia Tronson · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
35. Cytokines as diagnostic biomarkers in canine pyometra and sepsis
    Iulia Karlsson · 2015 · Epsilon Open Archive (Sveriges lantbruksuniversitet biblioteket (Swedish University of Agricultural Sciences))
36. Direct Implications between Prenatal Alcohol Consumption and Gut Microbiome in the Neurodevelopment of Mice Offspring – Focusing On Foetal Alcoholic Spectrum Disorders
    Cristiano Pedroso-Roussado, Fergus Michael Guppy, Lucas D. Bowler, João Inácio · 2022 · Preprints.org
37. An Examination of the Long-lasting Effects of Lipopolysaccharide-induced Sepsis on Cognitive and Affective Behaviour in Mice
    Seán T. Anderson · 2014 · Maynooth University ePrints and eTheses Archive (Maynooth University)
38. Transcriptional regulation of type I interferon responses of myeloid antigen presenting cells
    Wei Xiang Sin · 2016
39. Laboratory Animal Models to Mimic Human Sepsis: A Review
    Sudhir Verma · 2016
40. Functional analysis of epithelium-specific Ets transcription factor-1 in inflammation
    Chan Mi Lee · 2016 · TSpace (University of Toronto)
41. Apnea induction for invasive lung function testing in infant olive baboons: Comparison of intravenous propofol versus hyperventilation
    Vadim A. Ivanov, Roman F. Wolf, James F. Papin, Michael P. Anderson, Claude L. Hill, Charles Welliver · 2017 · Journal of Medical Primatology
42. Perioperative neutrophil immune function
    David J Cain · 2017 · UCL Discovery (University College London)
43. Long hidden sepsis subgroup may benefit from immune therapy
    Mark Tidswell · 2018 · Journal of Emergency and Critical Care Medicine
44. The Assessment of Hanging Behavior as a Measure of Mouse Welfare
    Ingita Mahendra Patel · 2018 · TSpace (University of Toronto)
45. Bacterial Targeting of Tumors
    David G. Bermudes · 2019 · Elsevier eBooks
46. A physiological model of the inflammatory-thermal-pain-cardiovascular interactions during a pathogen challenge
    A Dobréva, Renee Brady‐Nicholls, Kamila Larripa, Charles Puelz, Jesper Mehlsen, Mette Sofie Olufsen · 2019 · arXiv (Cornell University)
47. Long-Lasting Memory Impairments after Subchronic Immune Challenge
    Daria Tchessalova · 2019 · Deep Blue (University of Michigan)
48. Functional genomics approach to understanding sepsis heterogeneity
    Kieu Le · 2019
49. The role of venous return in organ perfusion
    Lex M. van Loon · 2019
50. Empty SV40 capsids increase survival of septic rats by eliciting numerous host signaling networks that participate in a number of systemic functions
    O. Ben-nun-shaul, Rohit Srivastava, S. Elgavish, Shashi Gandhi, Y. Nevo, Hadar Benyamini, A. Eden, A. Oppenheim · 2020 · OncoTarget
51. Mapping infectious disease mortality onto the within-host dynamics of pathogen growth
    Tim O’Sullivan, Kristofer Wollein Waldetoft, Sam P. Brown · 2020 · medRxiv
52. Therapeutic Efficacy of Mesenchymal Stromal Cell Derived Microparticles to Protect Against Pulmonary Capillary Barrier Permeability in Acute Respiratory Distress Syndrome
    Mazharul Maishan · 2018 · TSpace (University of Toronto)
53. Sepsis and Septic Shock; Current Treatment Dilemma and Role of Stem Cell Therapy in Pediatrics
    Gökçen Dinç, Zeynep Burçin Gönen, Jafar Soltani, Mehmet Doğanay · 2021 · Archives of Pediatric Infectious Diseases
54. Neutrophilic granulocytes: phagocytes and more
    Aleshina Gm · 2021 · Medical academic journal
55. Discovery and investigation of a novel role for mitochondrial prohibitin in mitigating acute heart failure in endotoxic shock
    Taylor Ann Mattox · 2014 · The Scholarship East Carolina University's Institutional Repository (East Carolina University)
56. An ex vivo porcine spleen perfusion as a model of bacterial sepsis_suppl
    Wen Yuan Chung · 2018 · ALTEX
57. Title: AKI and CKD Worsen Outcomes in Experimental Sepsis: Creating a Reverse-translational Model of Acute Peritoneal Infection and Recovery in an Immunocompromised Rodent
    Deana F. Floyd, James T. Colbert, Seth B. Furgeson, John R. Montford · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
58. Efficacy of antibiotic combinations in an experimental sepsis model with Pseudomonas aeruginosa
    Zerrin Aktaş, Neşe Sönmez, Lütfiye Öksüz, Ozden Buyukbaba Boral, Halim İşsever, Oral Öncül · 2023 · Brazilian Journal of Microbiology
59. Heterozygosity for Crohn’s Disease Risk Allele of ATG16L1 Protects against Bacterial Infection
    Xiaomin Yao, Eugene Rudensky, Patricia K. Martin, Erin E. Zwack, Zhengxiang He, Gláucia C. Furtado, Sérgio A. Lira, Victor J. Torres, Bo Shopsin, Ken Cadwell · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
60. Blockade of Cluster of Differentiation 38 Alleviates Sepsis-Induced Acute Lung Injury in Mice Through Inflammation Suppression via Regulating Toll-Like Receptor 4/Nuclear Factor kappa B p65
    Xian‐Jin Zhang, Hui Shen, Li Wang, Miaomiao Zhu, Yingzhi Wang · 2024 · Journal of Biomedical Nanotechnology
61. Natural genetic variation in wild-derived mice controls host survival and transcriptional responses during endotoxic shock
    Bristy Sabikunnahar, Julia Priscilla Snyder, Princess D. Rodriguez, Katherine J. Sessions, Eyal Amiel, Seth E. Frietze, Dimitry N. Krementsov · 2025 · ImmunoHorizons
62. Animal Models in Surgical Research
    Michelle M. Holland, Allan M. Goldstein, John Bart Rose · 2025 · Success in academic surgery
63. Astaxanthin Inhibits Lipopolysaccharide-Induced Immunosuppression in Macrophages
    Jiahui Wang, Zhiyong Wang, Wei Pei · 2025 · Jentashapir Journal of Cellular and Molecular Biology
64. Sphingosine-1-phosphate protects against sepsis-associated encephalopathy by suppressing heparanase-mediated endothelial glycocalyx degradation
    Ling Tang, Baojun Liang, Yuchen Zhang, Junjie Li, Yi Feng, Jia-Rong Huang, Xing Li, Jiajia Zhu · 2025 · European Journal of Pharmacology
65. Origins of human sensitivity to endotoxin and implications for sepsis therapeutic development
    Abby K. Long, Jessica F. Brinkworth · 2025 · Elsevier eBooks
66. Additional file 1 of LncRNA–mRNA expression profile and functional network of vascular dysfunction in septic rats
    Han, Ye-Chen, Shen, Zhu-Jun, Wang, Yi-Ning, Xiang, Ruo-Lan, Xie Hongzhi · 2024 · Figshare
67. Additional file 1 of A model of porcine polymicrobial septic shock
    Zurek-Leffers, Finnja Marie, Lehmann, Florian, Laura Brabenec, Sebastian Kintrup, Katharina E. M. Hellenthal, Kira Mersjann, Felicia Kneifel, Michael Heßler, Arnemann, Philip-Helge, Kampmeier, Tim-Gerald et al. · 2024 · Figshare
68. Additional file 1 of ABT-263 enhanced bacterial phagocytosis of macrophages in aged mouse through Beclin-1-dependent autophagy
    Zhang, Yu, Tang, Li-hua, Lu, Jia, Xu, Li-ming, Cheng, Bao-li, Xiong, Jun-yu · 2021 · Figshare
69. Additional file 1 of Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina
    Kaira A. Church, Derek Rodriguez, Difernando Vanegas, Irene L. Gutiérrez, Sandra M. Cardona, José L. M. Madrigal, Tejbeer Kaur, Astrid E. Cardona · 2023 · Figshare
70. Myocardial injury mediated by acute inflammation after abdominal surgery in mice: a mechanistic translational study
    Makishi Maeda, Yusuke Yoshikawa, Sho Ohno, Yasuaki Sawashita, Koki Nakamura, Masatoshi Kanda, Naoyuki Hirata, Michiaki Yamakage · 2026 · British Journal of Anaesthesia
71. Molecular Mechanisms of Preab-Tolc Mediated Polymyxin B Resistance and its Reversal by Sanguinarine in Enterobacter Cloacae Pol9
    Gongli Zong, Yongan Wang, Jiahui Wang, Minghui Yu, Peipei Zhang, Yayu Liu, Jiayi Han, Yuhan Zhang, Guangxiang Cao, Jiafang Fu · 2025 · SSRN Electronic Journal
72. Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury
    Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang · 2026 · Advanced Science
73. Dynamic gut responses to sepsis uncovered by multi-omics profiling in a rodent model
    Jingchao Lei, Jing Qi, Jia Zhai, Ziying Chen, Nanyi Li, Yao Zhang, Yishu Yuan, Chuanzheng Sun · 2026 · Communications Biology
74. Role of the innate immune response in vascular damage caused by Neisseria meningitidis infection
    Valeria Manriquez Rojas · 2018
75. Régulation de la réponse immunitaire au cours du sepsis
    Fanny Alby‐Laurent · 2018 · theses.fr (ABES)
76. Study of the blood-brain interface and glial cells during sepsis-associated encephalopathy : from imaging to histology
    Ibtihel Dhaya · 2017
77. Study of the role of inflammatory cell death in the regulation of pulmonary bacterial infections : Identification of novel factors involved in pulmonary pathology mediated by the Exotoxin U of P. aeruginosa
    Salimata Bagayoko · 2022 · theses.fr (ABES)
78. Emergence of NLRP1 inflammasome as a sensor of microbial virulence in human epithelium
    Miriam Pinilla · 2023 · theses.fr (ABES)
79. The ATP-binding cassette transporter CstA as a novel therapeutic target for treating carbapenem-resistant Enterobacteriaceae bacteria
    Jiafang Fu, Rong Wang, Yayu Liu, Gongli Zong, Peipei Zhang, Guangxiang Cao · 2026 · International Journal of Antimicrobial Agents
80. Dendrobine alleviates lung injury in septic mice by inhibiting mitochondrial-endoplasmic reticulum crosstalk-mediated NLRP3 inflammasome activation.
    Shichao Zhang, Kaihang Luo, Xinyue Wei, C. Qing, Jian-Guo Zhang, Huazhang Wei, Yongan Yan, Yu-Ting Yang, Zhen-Guo Zeng, Shuying Huang · 2026 · Journal of Pharmacological Sciences
81. Metabolic footprint of sepsis and septic shock: A narrative review
    Anjali Mishra, Deven Juneja · 2026 · World Journal of Critical Care Medicine
82. Development and validation of a rabbit model of Pseudomonas aeruginosa hyperdynamic septic shock for preclinical drug development
    N. D. Tran, N. T. Nguyen, Trang T. T. Vu, P. Diep, Naomi N Villescas, N. N. Nguyen, Kei Sato, W. Weiss, T. Doan, B. Diep · 2026 · Antimicrobial Agents and Chemotherapy
83. Source control within 12 h attenuates lung injury and systemic bacterial burden in a rat model of polymicrobial abdominal sepsis (cecal ligation and puncture)
    María Luisa Martínez, Eva Torrents, Marta Camprubí–Rimblas, Josep Bringué, Adrián Ceccato, Ricard Ferrer, Antonio Artigas, Raquel Guillamat‐Prats · 2026 · Intensive Care Medicine Experimental
84. Translating the pathophysiology of sepsis-associated acute kidney injury: From bench to bedside
    Mengfei Lu, Qi Zhang, Mingmin Pang, Haoyu Wang, Miaosa Zhang, Yihui Li, Hao Wang · 2026 · Journal of Intensive Medicine
85. Curcumin-encapsulated ROS-responsive nanoparticles for modulation of oxidative stress and inflammation in sepsis
    Cheng Zheng, Hong Chen, Weihao Jiang, Xiao Zheng Yang, Yifeng Mao, Jian Lan, X. L. Zhang, Changcan Shi, Qingqing Chen · 2026 · Journal of Materials Chemistry B
86. Tissue-specific inflammatory responses to systemic LPS in mice with LysM-lineage Hmgb1 deletion
    James Johnson, Angar Tsoggerel, Kathryn D. Fischer, Alexandru Movilă, Antentor Othrell Hinton Jr., Kimberly A. Sullivan · 2026 · Brain Behavior & Immunity - Health
87. Anti-inflammatory effects of JI-017 in cellular and an LPS-induced endotoxemia model
    Young Ha Kim, Sang-Eun Lee, Ga-Eun Choi, Daeun Kim, Cheon Chunhoo, Seong‐Gyu Ko · 2026 · Molecular Biology Reports
88. A Murine Model of Pseudomonas aeruginosa Pneumonia-Induced Sepsis-Associated Encephalopathy Reveals Upregulation of the NLRP3/Caspase-1/IL-1β Pathway
    Guanxian Li, Linlin Gao, Jinjin Li, Liying Wang, Weihui Wu, Xuehua Liu · 2026 · Brain Sciences
89. Effect of Ascorbate on Coagulation and Fibrinolytic Factors in the Septic Microvasculature
    Scott B. Swarbreck · 2014