The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.
The Atopic March: Progression from Atopic Dermatitis to Allergic Rhinitis and Asthma
Open accessAbstract
Atopic dermatitis (AD) is an inflammatory disease characterized by pruritic skin lesions. The pathogenesis of AD may include disrupted epidermal barrier function, immunodysregulation, and IgE-mediated sensitization to food and environmental allergens. AD is also part of a process called the atopic march, a progression from AD to allergic rhinitis and asthma. This has been supported by multiple cross-sectional and longitudinal studies and experimental data. Research on the mechanisms of AD has been centered on the adaptive immune system with an emphasis on the T-helper 1 (Th1)-Th2 paradigm. Recently, the conceptual focus has largely shifted to include a primary defect in the epithelial barrier as an initial event in AD providing a significant insight into the disease initiation and pointing to a complex secondary interplay of environmental and immunological sequelae with barrier disruption. Further understanding of AD will help the development of more effective treatment for AD and ultimately, preventative algorithms for the atopic march. In this review we highlight recent advances in our understanding of the pathogenesis of AD and the atopic march.
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New insights into atopic dermatitis
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Cytokine modulation of atopic dermatitis filaggrin skin expression
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Cited by
IgE and mast cells in allergic disease
Galli, S. J., & Tsai, M. (2012) · Nature Medicine · doi:10.1038/nm.2755 · Cited by 1,799
The multifunctional role of filaggrin in allergic skin disease
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Economic burden of inadequate management of allergic diseases in the European Union: a GA2LEN review
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Significance of Skin Barrier Dysfunction in Atopic Dermatitis
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Metadata
- Authors
- Zheng, T., Yu, J., Oh, M. H., & Zhu, Z.
- Venue
- Allergy, Asthma and Immunology Research
- Publisher
- XMLink
- Published
- 2011
- Volume
- 3
- Issue
- 2
- Pages
- 67
- ISSN
- 2092-7355 (ISSN-L)
- OpenAlex
- W2165676713
- Cited by
- 425
- References
- 74
- FWCI
- 33.27
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Zheng, T., Yu, J., Oh, M. H., & Zhu, Z. (2011). The Atopic March: Progression from Atopic Dermatitis to Allergic Rhinitis and Asthma. Allergy, Asthma and Immunology Research. https://doi.org/10.4168/aair.2011.3.2.67
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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