The DOI matches its Crossref record; 136 of the 136 references it cites were found in a registry or an index.
Clinical Biochemistry of Hepatotoxicity
Abstract
Liver plays a central role in the metabolism and excretion of xenobiotics which makes it highly susceptible to their adverse and toxic effects. Liver injury caused by various toxic chemicals or their reactive metabolites [hepatotoxicants) is known as hepatotoxicity. The present review describes the biotransformation of hepatotoxicants and various models used to study hepatotoxicity. It provides an overview of pathological and biochemical mechanism involved during hepatotoxicity together with alteration of clinical biochemistry during liver injury. The review has been supported by a list of important hepatotoxicants as well as common hepatoprotective herbs.
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Citations
Cites
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The current state of serum biomarkers of hepatotoxicity
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AASLD position paper: The management of acute liver failure†
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Cited by
Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protection
García-Niño, W. R., & Zazueta, C. (2015) · Pharmacological Research · doi:10.1016/j.phrs.2015.04.008 · Cited by 274
Metadata
- Authors
- P Sharma, O.
- Venue
- Journal of Clinical Toxicology
- Publisher
- OMICS Publishing Group
- Published
- 2014
- Volume
- 04
- Issue
- 01
- ISSN
- 2161-0495 (ISSN-L)
- OpenAlex
- W2103478791
- Cited by
- 305
- References
- 136
- FWCI
- 35.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- P Sharma, O. (2014). Clinical Biochemistry of Hepatotoxicity. Journal of Clinical Toxicology. https://doi.org/10.4172/2161-0495.s4-001
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
