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Cited by 42Pancreatic and Hepatic Oncology ResearchMinimally Invasive Surgical TechniquesPancreatitis Pathology and Treatment

Total pancreatectomy: Short- and long-term outcomes at a high-volume pancreas center

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Zakaria, Hazem M, Stauffer, John A, Raimondo, Massimo, Woodward, Timothy A, Wallace, Michael B, Asbun, Horacio J·2016·World Journal of Gastrointestinal Surgery
DOI 10.4240/wjgs.v8.i9.634PMC PMC5037337
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Abstract

AIM: To identify the current indications and outcomes of total pancreatectomy at a high-volume center. METHODS: A single institutional retrospective study of patients undergoing total pancreatectomy from 1995 to 2014 was performed. RESULTS: = 6, 5.8%). The mean age was 66.2 years, and 59 (57.3%) were female. Twenty-four patients (23.3%) underwent a laparoscopic total pancreatectomy. Splenic preservation and portal vein resection and reconstruction were performed in 24 (23.3%) and 18 patients (17.5%), respectively. The 90 d major complications, readmission, and mortality rates were 32%, 17.5%, and 6.8% respectively. The 1-, 3-, 5-, and 7-year survival for patients with benign indications were 84%, 82%, 79.5%, and 75.9%, and for malignant indications were 64%, 40.4%, 34.7% and 30.9%, respectively. CONCLUSION: Total pancreatectomy, including laparoscopic total pancreatectomy, appears to be an appropriate option for selected patients when treated at a high-volume pancreatic center and through a multispecialty approach.

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  • In the pre-CGM era, total loss of glycemic control was associated with severe complications in patients undergoing total pancreatectomy.

    “In the pre-CGM era, the total loss of glycemic control was associated with severe complications in patients undergoing total pancreatectomy [35,66,69].”

    From An Uncommon Cause of Recurrent Presyncope, Dizziness, and Tachycardia: A Case Report of Diffuse, Adult-Onset Nesidioblastosis/Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome (NIPHS) (2023) · cites this paper as [69]

    The Discussion (page not provided) says diabetes after total pancreatectomy can be difficult to control and cites reported deaths from hypoglycemia, though none occurred in this study. The Methods define major glycemic events as complications or readmissions related to severe hyperglycemia or hypoglycemia. The paper does not characterize these outcomes as a total loss of glycemic control or specifically place them in a pre-CGM era. (LLM, conf=0.83)

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Cited by

Sorted by citations

Authors
Zakaria, H. M., Stauffer, J. A., Raimondo, M., Woodward, T. A., Wallace, M. B., & Asbun, H. J.
Affiliations
Mayo Clinic (US)
Corresponding author
Stauffer, John A
ORCID
Venue
World Journal of Gastrointestinal Surgery
Publisher
Baishideng Publishing Group Inc.
Published
2016
Volume
8
Issue
9
Pages
634
ISSN
1948-9366 (ISSN-L)
DOI
10.4240/wjgs.v8.i9.634
PMC
PMC5037337
OpenAlex
W2521936500
Cited by
42
References
1
Citations by year
2026: 1 · 2025: 4 · 2024: 3 · 2023: 3 · 2022: 5 · 2021: 7 · 2020: 7 · 2019: 7 · 2018: 1 · 2017: 4
FWCI
2.16
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • World Journal of Gastrointestinal Surgery (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Oncology › Pancreatic and Hepatic Oncology Research
  • Health Sciences › Medicine › Surgery › Minimally Invasive Surgical Techniques
  • Health Sciences › Medicine › Surgery › Pancreatitis Pathology and Treatment
Keywords
total pancreatectomy, postoperative complications, survival outcomes, benign pancreatic disease, pancreatic cancer, spleen preservation, portal vein reconstruction, hospital readmission, mortality

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