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Telomere dynamics in induced pluripotent stem cells: Potentials for Human disease modeling

Ly, Hinh·2011·World Journal of Stem Cells

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Figure 1 Telomerase enzyme. Simplified illustration of the telomerase enzyme showing its main components: hTERT, hTERC, Dyskerin, NOP10, NHP2, GAR1, and TCAB1. Functional regions of the hTERC RNA (template, pseudoknot, CR4CR5, Box H/ACA, and CR7) are indicated. Mutations in hTERT, hTERC, TCAB1, NOP10 or Dyskerin have been shown to be associated with a severe form of human bone-marrow deficiency known as dyskeratosis congenita.
Figure 1 Telomerase enzyme. Simplified illustration of the telomerase enzyme showing its main components: hTERT, hTERC, Dyskerin, NOP10, NHP2, GAR1, and TCAB1. Functional regions of the hTERC RNA (template, pseudoknot, CR4CR5, Box H/ACA, and CR7) are indicated. Mutations in hTERT, hTERC, TCAB1, NOP10 or Dyskerin have been shown to be associated with a severe form of human bone-marrow deficiency known as dyskeratosis congenita.CC-BY-NC · From the PDF

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Metadata

Authors
Ly, H.
Venue
World Journal of Stem Cells
Published
2011
Volume
3
Issue
10
Pages
89
ISSN
1948-0210
Cited by
12
References
17
Language
en

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Ly, H. (2011). Telomere dynamics in induced pluripotent stem cells: Potentials for Human disease modeling. World Journal of Stem Cells. https://doi.org/10.4252/wjsc.v3.i10.89