The DOI matches its Crossref record; 127 of the 127 references it cites were found in a registry or an index.
Antimalarial Drug Resistance: Literature Review and Activities and Findings of the ICEMR Network
Open accessAbstract
Antimalarial drugs are key tools for the control and elimination of malaria. Recent decreases in the global malaria burden are likely due, in part, to the deployment of artemisinin-based combination therapies. Therefore, the emergence and potential spread of artemisinin-resistant parasites in southeast Asia and changes in sensitivities to artemisinin partner drugs have raised concerns. In recognition of this urgent threat, the International Centers of Excellence for Malaria Research (ICEMRs) are closely monitoring antimalarial drug efficacy and studying the mechanisms underlying drug resistance. At multiple sentinel sites of the global ICEMR network, research activities include clinical studies to track the efficacies of antimalarial drugs, ex vivo/in vitro assays to measure drug susceptibilities of parasite isolates, and characterization of resistance-mediating parasite polymorphisms. Taken together, these efforts offer an increasingly comprehensive assessment of the efficacies of antimalarial therapies, and enable us to predict the emergence of drug resistance and to guide local antimalarial drug policies. Here we briefly review worldwide antimalarial drug resistance concerns, summarize research activities of the ICEMRs related to drug resistance, and assess the global impacts of the ICEMR programs.
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Cites
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Cited by
Antimalarial Drug Resistance: A Threat to Malaria Elimination
Menard, D., & Dondorp, A. (2017) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a025619 · Cited by 499
Plantone, D., & Koudriavtseva, T. (2018) · Clinical Drug Investigation · doi:10.1007/s40261-018-0656-y · Cited by 305
Cytokines and Chemokines in Cerebral Malaria Pathogenesis
Dunst, J., Kamena, F., & Matuschewski, K. (2017) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2017.00324 · Cited by 264
Moles, E., Galiano, S., Gomes, A., Quiliano, M., Teixeira, C., Aldana, I., Gomes, P., & Fernàndez-Busquets, X. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.08.020 · Cited by 41
Malaria – Current Treatment Options
Virginia, D. M., Shegokar, R., & Pathak, Y. (2023) · Malarial Drug Delivery Systems · doi:10.1007/978-3-031-15848-3_4 · Cited by 1
Metadata
- Authors
- Cui, L., Mharakurwa, S., Ndiaye, D., Rathod, P. K., & Rosenthal, P. J.
- Venue
- The American Journal of Tropical Medicine and Hygiene
- Published
- 2015-09-02
- Volume
- 93
- Issue
- 3_Suppl
- Pages
- 57-68
- ISSN
- 0002-9637 (ISSN-L)
- 1476-1645
- OpenAlex
- W2217812638
- Cited by
- 305
- References
- 127
- FWCI
- 25.23
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Cui, L., Mharakurwa, S., Ndiaye, D., Rathod, P. K., & Rosenthal, P. J. (2015). Antimalarial Drug Resistance: Literature Review and Activities and Findings of the ICEMR Network. The American Journal of Tropical Medicine and Hygiene. https://doi.org/10.4269/ajtmh.15-0007
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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