The DOI matches its Crossref record.
MICROSPORIDIOSIS IN TRAVEL-ASSOCIATED CHRONIC DIARRHEA IN IMMUNE-COMPETENT PATIENTS
Abstract
We analyzed retrospectively 21 immune-competent travelers with chronic traveler’s diarrhea (3–6 weeks) after returning from recreational travel to the tropics with stool samples positive for microsporidia. Nine patients had been treated with albendazole and 12 patients had been treated symptomatically. Diarrhea resolved in 8 of 9 and 12 of 12 patients, respectively. In the albendazole group, Encephalitozoon intestinalis was cleared in 4 of 4 patients and Enterocytozoon bieneusi persisted in 7of 7 patients (2 patients were lost to follow-up). In the symptomatic treated group microsporidia persisted in stool samples of all patients. We conclude that there is only a transient correlation between detection of microsporidia in stool and gastrointestinal symptoms, and suggest that microsporidia infection may cause clinical symptoms during the early stages of infection that resolve even though the microsporidia may persist.
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“However, E. bieneusi infection was not successfully cured using albendazole (800 mg daily for 28 days), with parasites not completely cleared in small-bowel biopsies of the patients [299–302].”
From Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update (2021) · cites this paper as [301]
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The first 1000 cultured species of the human gastrointestinal microbiota
Rajilić-Stojanović, M., & de Vos, W. M. (2014) · FEMS Microbiology Reviews · doi:10.1111/1574-6976.12075 · Cited by 1,182
Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update
Chai, J.-Y., Jung, B.-K., & Hong, S.-J. (2021) · The Korean Journal of Parasitology · doi:10.3347/kjp.2021.59.3.189 · Cited by 286
Metadata
- Authors
- WICHRO, E., HOELZL, D., KRAUSE, R., BERTHA, G., REINTHALER, F., & WENISCH, C.
- Affiliations
- Medical University of Graz (AT)
- Department of Internal Medicine, University Hospital Graz, Medical University, Graz, Austria; Institute of Hygiene, Medical University, Graz, Austria
- Corresponding author
- WENISCH, CHRISTOPH
- Venue
- The American Journal of Tropical Medicine and Hygiene
- Published
- 2005-08
- Volume
- 73
- Issue
- 2
- Pages
- 285-287
- ISSN
- 0002-9637 (ISSN-L)
- OpenAlex
- W2159864771
- Cited by
- 73
- References
- 0
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 2 · 2023: 3 · 2022: 3 · 2021: 4 · 2020: 1 · 2019: 1 · 2018: 1 · 2017: 3 · 2016: 1 · 2015: 3 · 2014: 7 · 2013: 5 · 2012: 8
- FWCI
- 2.29
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Tropical Medicine and Hygiene (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Parasitology › Parasitic Infections and Diagnostics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Travel-related health issues
- Health Sciences › Medicine › Infectious Diseases › Viral gastroenteritis research and epidemiology
- Keywords
- microsporidiosis, chronic diarrhea, traveler's diarrhea, Encephalitozoon intestinalis, Enterocytozoon bieneusi, albendazole, stool antigen test, persistent infection, tropical travel
- MeSH terms
- Adolescent, Adult, Animals, Antiprotozoal Agents, Chronic Disease, Diarrhea, Feces, Female, Humans, Immunocompetence, Intestinal Diseases, Parasitic, Male, Middle Aged, Retrospective Studies, Travel, Albendazole, Encephalitozoon, Microsporidiosis, Encephalitozoonosis, Enterocytozoon
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