CoChat
Sign Up
Cited by 13Sperm and Testicular FunctionReproductive Health and TechnologiesReproductive Biology and Fertility

The relationship between semen parameters in processed and unprocessed semen with intrauterine insemination success rates

Open access
Mollaahmadi, Leila, Keramat, Afsaneh, Ghiasi, Ashraf, Hashemzadeh, Mozhgan·2019·Journal of the Turkish-German Gynecological Association
DOI 10.4274/jtgga.galenos.2018.2018.0089PMC PMC6501869
Open this paper in CoChat — free account

Abstract

Objective: To evaluate the relationship between semen parameters and intrauterine insemination (IUI) success rates. Material and Methods: This retrospective study was conducted during a 4-year period (2011-2015) on the medical records of 350 couples admitted to the infertility center of Beast Hospital in Tehran. The participants’ data such as age, duration of infertility, semen parameters [including volume, concentration, motility, normal morphology and total motile sperm count (TMSC)] before and after sperm processing, as well as the IUI results were extracted from the patients’ records. Only the first IUI cycle of the couples was considered. The main outcome criterion for the IUI success was serum positive beta human chorionic gonadtotropin 14 days after IUI. The collected data were analyzed using the Mann-Whitney U test, chi-square, and Fisher’s exact tests. Results: The overall pregnancy rate for each couple was reported as 23.42% (82/350). There was no significant difference in the mean age of the couple and infertility duration between the groups who achieved pregnancy and those who failed. The two groups showed no significant differences in pre and post processing of semen parameters (including volume, concentration and TMSC). Sperm motility and normal sperm morphology before and after sperm processing were significantly different between the two groups, respectively (p=0.023 before sperm processing and p=0.032 after) (p=0.032 before sperm processing and p=0.007 after). Conclusion: Sperm motility and normal sperm morphology have an effect in IUI success.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.4274/jtgga.galenos.2018.2018.0089

Cites

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

No references could be resolved yet.

Research works printed but not linked: 35

  1. [1]De Sutter P Rational diagnosis and treatment in infertility Best Practice Res Clin Obstet Gynaecol 2006 20 647 64 16769249
  2. [3]Erdem A Erdem M Atmaca S Korucuoglu U Karabacak O Factors affecting live birth rate in intrauterine insemination cycles with recombinant gonadotrophin stimulation Reprod Biomed Online 2008 17 199 206 18681993
  3. [4]Cantineau AE Cohlen BJ Al-Inany H Heineman MJ Intrauterine insemination versus fallopian tube sperm perfusion for non tubal infertility Cochrane Database Syst Rev 2004 CD001502. 15266448
  4. [6]Badawy A Elnashar A Eltotongy M Effect of sperm morphology and number on success of intrauterine insemination Fertil Steril 2009 91 777 81 18304534
  5. [7]Atasever M Kalem MN Hatırnaz Ş Hatırnaz E Kalem Z Kalaylıoğlu Z Factors affecting clinical pregnancy rates after IUI for the treatment of unexplained infertility and mild male subfertility J Turk Ger Gynecol Assoc 2016 17 134 8 27651720 PMC5019828
  6. [8]Jellad S Basly M Chibani M Rachdi R Predictive factors for intrauterine insemination success: analysis of semen parameters affecting outcome The Internet Journal of Urology 2014 12 1 7
  7. [9]Schulte RT Keller LM Hiner MR Ohl DA Smith GD Temporal decreases in sperm motility: Which patients should have motility checked at both 1 and 2 hours after collection? J Androl 2008 29 558 63 18539585
  8. [10]Ruiter-Ligeti J Agbo C Dahan M The impact of semen processing on sperm parameters and pregnancy rates after intrauterine insemination Minerva Ginecol J 2017 69 218 24 PMC6455807 27990794
  9. [12]Luco SM Agbo C Behr B Dahan MH The evaluation of pre and post processing semen analysis parameters at the time of intrauterine insemination in couples diagnosed with male factor infertility and pregnancy rates based on stimulation agent. A retrospective cohort study Eur J Obstet Gynecol Reprod Biol 2014 179 159 62 24965998 PMC4144991
  10. [14]Koyun Ok E Doğan ÖE Okyay RE Gülekli B The effect of postwash total progressive motile sperm count and semen volume on pregnancy outcomes in intrauterine insemination cycles: a retrospective study J Turk Ger Gynecol Assoc 2013 14 142 5 24592093 PMC3928411
  11. [15]Hassan N Agbo C Dahan MH Pregnancy rates unaffected by sperm count in intrauterine insemination: a retrospective cohort study Minerva Ginecol 2017 69 6 12 27098392
  12. [16]Van Voorhis BJ Barnett M Sparks AET Syrop CH Rosenthal G Dawson J Effect of the total motile sperm count on the efficacy and cost-effectiveness of intrauterine insemination and in vitro fertilization Fertil Steril 2001 75 661 8 11287015
  13. [17]Miller DC Hollenbeck BK Smith GD Randolph JF Christman GM Smith YR et al Processed total motile sperm count correlates with pregnancy outcome after intrauterine insemination Urology 2002 60 497 501 12350496
  14. [18]Xiao CW Agbo C Dahan MH Comparison of pregnancy rates in pre-treatment male infertility and low total motile sperm count at insemination Arch Gynecol Obstet 2016 293 211 7 26288981
  15. [20]Tay PY Raj VR Kulenthran A Sitizawiah O Prognostic factors influencing pregnancy rate after stimulated intrauterine insemination Med J Malaysia 2007 62 286 9 18551930
  16. [21]Yousefi B Azargon A Predictive factors of intrauterin insemination success of women with infertility over 10 years J Pak Med Assoc 2011 61 165 8 21375168
  17. [22]Zadehmodarres S Oladi B Saeedi S Jahed F Ashraf H Intrauterine insemination with husband semen: an evaluation of pregnancy rate and factors affecting outcome J Assist Reprod Genet 2009 26 7 11 19030984 PMC2649332
  18. [23]Ghaffari F Sadatmahalleh SJ Akhoond MR Eftekhari Yazdi P Zolfaghari Z Evaluating the effective factors in pregnancy after intrauterine insemination: a retrospective study Int J Steril 2015 9 300 8 PMC4671382 26644852
  19. [24]Tomlinson MJ Amissah-Arthur JB Thompson KA Kasraie JL Bentick B Prognostic indicators for intrauterine insemination (IUI): statistical model for IUI success Hum Reprod 1996 11 1892 6 8921060
  20. [25]Frederick JL Denker MS Rojas A Horta I Stone SC Asch RH et al Is there a role for ovarian stimulation and intra-uterine insemination after age 40? Hum Reprod 1994 9 2284 96 7714145
  21. [26]Ganguly I Singh A Bhandari S Agrawal P Gupta N Pregnancy predictors after intrauterine insemination in cases of unexplained infertility: a prospective study Int J Reprod Med 2016 2016 5817823 27738654 PMC5050366
  22. [27]Yildirim G Turkgeldi LS Koroglu N Guler S Talmac M Predictive factors for pregnancy outcome following controlled ovarianstimulation and intrauterine insemination J Park Med Assoc 2017 67 422 7 28303993
  23. [28]Sharma R Agarwal A Rohra VK Assidi M Abu-Elmagd M Turki RF Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring Reprod Biol Endocrinol 2015 13 35 25928123 PMC4455614
  24. [29]Merviel P Heraud MH Grenier N Lourdel E Sanguinet P Copin H Predictive factors for pregnancy after intrauterine insemination (IUI): an analysis of 1038 cycles and a review of the literature Fertil Steril 2010 93 79 88 18996517
  25. [30]Dadkhah F Nahabidian A Ahmadi GH The correlation between semen parameters in processed and unprocessed semen with pregnancy rate in intrauterine insemination in the treatment of male factor infertility Urol J 2004 1 273 5 17914706
  26. [31]Yavuz A Demirci O Sözen H Uludoğan M Predictive factors influencing pregnancy rates after intrauterine insemination Iran J Reprod Med 2013 11 227 34 24639750 PMC3943223
  27. [33]Ibérico G Vioque J Ariza N Lozano JM Roca M Llácer J et al Analysis of factors influencing pregnancy rates in homologous intrauterine insemination Fertil Steril 2004 81 1308 13 15136095
  28. [34]Zhao Y Vlahos N Wyncott D Petrella C Garcia J Zacur H et al Impactof semen characteristics on the success of intrauterine insemination J Assist Reprod Genet 2004 21 143 8 15279320 PMC3455523
  29. [35]Matorras R Corcostegui B Perez C Mandiola M Mendoza R Rodriguez-Escudero FJ Sperm morphology analysis (strict criteria) in male infertility is not a prognostic factor in intrauterine insemination with husband’s sperm Fertil Steril 1995 63 608 11 7851595
  30. [36]Aboutorabi R Dayani M Dastgerdi NM Effects of main semen parameters on intrauterian insemination (IUI) outcome Journal of Isfahan Medical School 2010 28 621 31
  31. [37]Lemmens L Kos S Beijer C Brinkman JW van der Horst FA van den Hoven L et al Predictive value of sperm morphology and progressively motile sperm count for pregnancy outcomes in intrauterine insemination Fertil Steril 2016 105 1462 8 26930619
  32. [38]Tan O Ha T Carr BR Nakonezny P Doody KM Doody KJ Predictive value of postwashed total progressively motile sperm count using CASA estimates in 6871 non-donor intrauterine insemination cycles J Assist Reprod Genet 2014 31 1147 53 25106939 PMC4156954
  33. [39]Tournays H Evidence Based management of male subfertility Curr Opin Obhstet Gynecol 2006 18 253 9 16735823
  34. [40]Park SJ Alvarez JR Weiss G Von Hagen S Smith D McGovern PG Ovulatory status and follicular response predict success of clomiphene citrate-intrauterin insemination Fertil Steril 2007 87 1102 7 17261288
  35. [41]Aboutorabi R Hojat Hi Mehrabi-Koushki A Baghazade Sh The effects of main semen parameters on intra-uterine insemination (IUI) Outcome Journal of Isfahan Medical School 2013 31 1723 34

Cited by

Sorted by citations

Authors
Mollaahmadi, L., Keramat, A., Ghiasi, A., & Hashemzadeh, M.
Affiliations
Shahroud University of Medical Sciences (IR)
Corresponding author
Mollaahmadi, Leila
ORCID
Venue
Journal of the Turkish-German Gynecological Association
Publisher
Galenos Yayinevi
Published
2019-03-01
Volume
20
Issue
1
Pages
1-7
ISSN
  • 1309-0380 (ISSN-L)
  • 1309-0399
DOI
10.4274/jtgga.galenos.2018.2018.0089
PMC
PMC6501869
OpenAlex
W2913430471
Cited by
13
References
0
Citations by year
2026: 1 · 2025: 2 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 1 · 2020: 1 · 2017: 1
FWCI
1.20
Type
journal article
Language
en
Open access
Locations
  • Journal of the Turkish-German Gynecological Association (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
  • Shahroud University of Medical Sciences
  • Student Research Committee, Tabriz University of Medical Sciences
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
  • Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
Keywords
intrauterine insemination, semen parameters, sperm processing, sperm motility, total motile sperm count, male infertility, pregnancy rate, beta-human chorionic gonadotropin

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review