Skin hydration in postmenopausal women: argan oil benefit with oral and/or topical use
Open accessAbstract
THE AIM OF THIS STUDY: The aim of this study was to evaluate the effect of daily consumption and/or application of argan oil on skin hydration in postmenopausal women. MATERIAL AND METHODS: Sixty postmenopausal women consumed butter during the stabilization period and were randomly divided into two groups for the intervention period: the treatment group absorbed alimentary argan oil (n = 30) and the control group olive oil (n = 30). Both groups applied cosmetic argan oil in the left volar forearm during a sixty days' period. Evaluation of skin hydration, i.e. transepidermal water loss (TEWL) and water content of the epidermis (WCE) on both volar forearms of the two groups, were performed during three visits at D0, D30 and after sixty days (D60) of oils treatment. RESULTS: The consumption of argan oil has led to a significant decrease in TEWL (p = 0.023) and a significant increase in WCE (p = 0.001). The application of argan oil has led to a significant decrease in TEWL (p = 0.01) and a significant increase in WCE (p < 0.001). CONCLUSIONS: Our findings suggest that the daily consumption and application of argan oil have improved the skin hydration by restoring the barrier function and maintaining the water-holding capacity.
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Daily topical application of argan oil improves skin hydration by restoring barrier function and maintaining water-holding capacity.
“Daily topical application of argan oil has also been shown to improve skin elasticity [81] and skin hydration by restoring the barrier function and maintaining the water-holding capacity [123].”
From Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils (2017) · cites this paper as [123]
The Discussion reports improved hydration, barrier function, and water-holding capacity after 60 days of daily argan-oil use in postmenopausal women; the Abstract’s Results also report significant changes after topical application. The citing sentence omits that population and duration, making the finding sound more general than the study establishes. (LLM, conf=0.84)
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Cites
Dietary nutrient intakes and skin-aging appearance among middle-aged American women
Cosgrove, M. C., Franco, O. H., Granger, S. P., Murray, P. G., & Mayes, A. E. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.4.1225 · Cited by 180 · see citing works
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Research works printed but not linked: 26
- [1]Nakagawa N Sakai S Matsumoto M Relationship between NMF (lactate and potassium) content and the physical properties of the stratum corneum in healthy subjects J Invest Dermatol 2004 122 755 763 15086563
- [2]Ponec M Weerheim A Lankhorst P Wertz P New acylceramide in native and reconstructed epidermis J Invest Dermatol 2003 120 581 588 12648220
- [3]Jungersted JM Hellgren LI Jemec GBE Agner T Lipids and skin barrier function – a clinical perspective Contact Dermatitis 2008 58 255 262 18416754
- [4]Raney SG Hope MJ The effect of bilayer and hexagonal HII phase lipid films on transepidermal water loss Exp Dermatol 2006 15 493 500 16761957
- [5]Breternitz M Kowatzki D Langenauer M Placebo-controlled, double-blind, randomized, prospective study of a glycerol-based emollient on eczematous skin in atopic dermatitis: biophysical and clinical evaluation Skin Pharmacol Physiol 2008 21 39 45 18025807
- [6]Dunn L Damesyn M Moore A Does estrogen prevent skin aging?: results from the First National Health and Nutritional Examination Survey Arch Dermatol 1997 133 339 342 9080894
- [7]Antoine C Liebens F Carly B Influence of HRT on prognostic factors for breast cancer: a systematic review after the Women's Health Initiative trial Hum Reprod 2004 19 741 756 14998980
- [8]Berrougui H Ettaib A Herrera Gonzalez MD Hypolipidemic and hypocholesterolemic effect of argan oil (Argania spinosa L.) in Meriones shawi rats J Ethnopharmacol 2003 89 15 18 14522427
- [9]Cherki M Berrougui H Drissi A Argan oil: Which benefits on cardiovascular diseases? Pharmacol Res 2006 54 1 5 16554174
- [10]Bellahcen S Mekhfi H Ziyyat A Prevention of chemically induced diabetes mellitus in experimental animals by virgin argan oil Phytother Res 2012 26 180 185 21584872
- [11]Azizi F Ainy E Coronary heart disease risk factors and menopause: a study in 1980 Tehranian women, the Tehran Lipid and Glucose Study Climactric 2003 6 330 336 15006254
- [12]Bellakhdar J La pharmacopée marocaine traditionnelle 1997 Paris Ibis Press 486 488
- [14]Derouiche A Cherki M Drissi A Nutritional intervention study with argan oil in man: effects on lipids and apolipoproteins Ann Nutr Metab 2005 49 196 201 16020940
- [15]Rogiers V EEMCO guidance for the assessment of transepidermal water loss in cosmetic sciences Skin Pharmacol Appl Skin Physiol 2001 14 117 128 11316970
- [16]Berardesca E EEMCO guidance for the assessment of stratum corneum hydration: Electrical methods Skin Res Technol 1997 3 126 132 27333374
- [17]Urano R Sakabe K Seiki K Ohkido M Female sex hormone stimulates cultured human keratinocyte proliferation and its RNA- and protein-synthetic activities J Dermatol Sci 1995 9 176 184 8664215
- [18]Fluhr JW Feingold KR Elias PM Transepidermal water loss reflects permeability barrier status: validation in human and rodent in vivo and ex vivo models Exp Dermatol 2006 15 483 492 16761956
- [19]Fluhr JW Miteva M Primavera G Functional assessment of a skin care system in patients on chemotherapy Skin Pharmacol Physiol 2007 20 253 259 17587889
- [20]Pirot F Falson F Agache P Humbert P Skin barrier function Measuring the skin 2004 Berlin Springer-Verlag
- [22]Ollivier D Artaud J Pinatel C Triacylglycerol and fatty acid compositions of French virgin olive oils. Characterization by chemometrics J Agric Food Chem 2003 51 5723 5731 12952425
- [23]Khallouki F Younos C Soulimani R Consumption of argan oil (Morocco) with its unique profile of fatty acids, tocopherols, squalene, sterols and phenolic compounds should confer valuable cancer chemopreventive effects Eur J Cancer Prev 2003 12 67 75 12548113
- [25]Bouwstra JA Gooris GS Dubbelaar FER Role of ceramide 1 in the molecular organization of the stratum corneum lipids J Lipid Res 1998 39 186 196 9469597
- [26]Hou SYE Mitra AK White SH Membrane structures in normal and essential fatty acid-deficient stratum corneum: characterization by ruthenium tetroxide staining and X-ray diffraction J Invest Dermatol 1991 96 215 223 1991982
- [27]Imokawa G Yada Y Higuchi K Pseudo acylceramide with linoleic acid produces selective recovery of diminished cutaneous barrier function in essential fatty acid deficient rats and has an inhibitory effect on epidermal hyperplasia J Clin Invest 1994 94 89 96 8040295 PMC296285
- [28]Sertznig P Seifert M Tilgen W Reichrath J Peroxisome proliferator-activated receptors (PPARs) and the human skin: importance of PPARs in skin physiology and dermatologic diseases Am J Clin Dermatol 2008 9 15 31 18092840
- [29]Man MQ Choi EH Schmuth M Basis for improved permeability barrier homeostasis induced by PPAR and LXR activators: liposensors stimulate lipid synthesis, lamellar body secretion, and post-secretory lipid processing J Invest Dermatol 2006 126 386 392 16374473
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Sorted by citations
Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils
Lin, T.-K., Zhong, L., & Santiago, J. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms19010070 · Cited by 759 · see citing works
“Daily topical application of argan oil has also been shown to improve skin elasticity [81] and skin hydration by restoring the barrier function and maintaining the water-holding capacity [123].”
BackgroundFernandes, A., Rodrigues, P. M., Pintado, M., & Tavaria, F. K. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154824 · Cited by 264 · see citing works
- Authors
- Boucetta, K. Q., Charrouf, Z., Derouiche, A., Rahali, Y., & Bensouda, Y.
- Affiliations
- Mohammed V University (MA)
- University of Hassan II Casablanca (MA)
- Corresponding author
- Bensouda, Yahya
- Venue
- Menopausal Review
- Publisher
- Termedia Sp. z.o.o.
- Published
- 2014
- Volume
- 5
- Issue
- 5
- Pages
- 280-288
- ISSN
- 1643-8876 (ISSN-L)
- PMC
- PMC4520377
- OpenAlex
- W2170138432
- Cited by
- 31
- References
- 1
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 6 · 2022: 4 · 2021: 4 · 2019: 6 · 2018: 4 · 2017: 2
- FWCI
- 0.73
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc-sa
- Locations
- Menopause Review/Przegląd Menopauzalny (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Keywords
- argan oil, skin hydration, postmenopausal women, transepidermal water loss, skin barrier function, oral supplementation, topical application, olive oil, menopause
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