The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.
Significance of immunohistochemistry in breast cancer
Open accessAbstract
The biological characteristics of the tumour are used to estimate prognosis and select appropriate systemic therapy for patients with (breast) cancer. The advent of molecular technology has incorporated new biomarkers along with immunohistochemical and serum biomarkers. Immunohistochemical markers are often used to guide treatment decisions, to classify breast cancer into subtypes that are biologically distinct and behave differently, and both as prognostic and predictive factors. Steroid hormone receptors, markers of tumour proliferation, and factors involved in angiogenesis and apoptosis are of scientific interest. In this review we will provide information on the immunohistochemical markers used in the management of breast cancer patients using available data from the literature. We consider the utility of established immunohistochemical markers, and discuss the challenges involved in integrating novel molecular markers into clinical practice.
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Cited by
Digital pathology and artificial intelligence
Niazi, M. K. K., Parwani, A. V., & Gurcan, M. N. (2019) · The Lancet Oncology · doi:10.1016/s1470-2045(19)30154-8 · Cited by 1,232
Tumor biomarkers for diagnosis, prognosis and targeted therapy
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Metadata
- Authors
- Zaha, D. C.
- Venue
- World Journal of Clinical Oncology
- Publisher
- Baishideng Publishing Group Inc.
- Published
- 2014
- Volume
- 5
- Issue
- 3
- Pages
- 382
- ISSN
- 2218-4333 (ISSN-L)
- OpenAlex
- W2049420719
- Cited by
- 277
- References
- 58
- FWCI
- 2.24
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
