The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Evaluation of subcutaneous immunotherapy with birch pollen extract for pollen-food allergy syndrome
Abstract
Some patients with pollen-food allergy syndrome (PFAS) develop systemic symptoms along with oral allergy syndrome upon ingesting processed foods as well as raw fruits and vegetables. This study aimed to investigate the efficacy of subcutaneous immunotherapy with birch pollen extract for patients with PFAS associated with soybean allergy. Subcutaneous immunotherapy with birch pollen extract was introduced in 6 patients with PFAS caused by alder/birch pollen and soybean allergy. An oral food challenge for ingestible amount of soy milk was performed before and 1 year after initiating subcutaneous immunotherapy with birch pollen extract. Before the treatment, the median intake of soy milk was 1.5 mL (interquartile range [IQR], 1-2 mL). One year after the treatment initiation, the median intake of soy milk increased significantly to 150 mL (IQR, 20-200 mL). Systemic reactions occurred in 4 of 6 patients in the rapid escalation phase of the treatment. The results thus suggest that subcutaneous immunotherapy with birch pollen extract could be beneficial for patients with PFAS associated with soybean allergy despite concerns regarding systemic reactions.
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“For instance, birch pollen AIT can alleviate symptoms triggered by PR-10 proteins found in foods like apples (Mal d 1), hazelnuts (Cor a 1), and carrots (Dau c 1) [265]”
From Pollen–Food Allergy Syndrome: Allergens, Clinical Insights, Diagnostic and Therapeutic Challenges (2024) · cites this paper as [265]
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Cites
Allergen immunotherapy: A practice parameter third update
Cox, L., Nelson, H., Lockey, R., Calabria, C., Chacko, T., Finegold, I., Nelson, M., Weber, R., Bernstein, D. I., Blessing-Moore, J., et al. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.09.034 · Cited by 1,256
Asero (1998) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.1998.00399.x · Cited by 195 · cited 2×
“The efficacy of AIT with Bet v1, the major birch pollen allergen has been evaluated with apple OFC in some studies [4-6].”
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Research works printed but not linked: 7
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Pollen–Food Allergy Syndrome: Allergens, Clinical Insights, Diagnostic and Therapeutic Challenges
Haidar, L., Bănărescu, C. F., Uța, C., Moldovan, S. I., Zimbru, E.-L., Zimbru, R.-I., Ciurariu, E., Georgescu, M., & Panaitescu, C. (2024) · Applied Sciences · doi:10.3390/app15010066 · Cited by 21
Metadata
- Authors
- Hamada, M., Kagawa, M., & Tanaka, I.
- Venue
- Asia Pacific Allergy
- Published
- 2021-10
- Volume
- 11
- Issue
- 4
- Pages
- e39
- ISSN
- 2233-8276
- PMC
- PMC8563098
- Cited by
- 12
- References
- 2
- Language
- en
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- Hamada, M., Kagawa, M., & Tanaka, I. (2021). Evaluation of subcutaneous immunotherapy with birch pollen extract for pollen-food allergy syndrome. Asia Pacific Allergy. https://doi.org/10.5415/apallergy.2021.11.e39
