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Cited by 395

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

Osteonecrosis of the Femoral Head

Lavernia, Carlos J., Sierra, Rafael J., Grieco, Francisco R.·1999·Journal of the American Academy of Orthopaedic Surgeons

Abstract

New cases of osteonecrosis of the femoral head in the United States number between 10,000 and 20,000 per year. This disease usually affects patients in their late 30s and early 40s. Although a number of authors have related specific risk factors to this disease, its etiology, pathogenesis, and treatment remain a source of considerable controversy. This disorder has been associated with corticosteroid use, substance abuse, and various systemic medical conditions. Either direct damage to osteocytes (e.g., by toxin production) or indirect damage (e.g., due to disorders in fat metabolism or hypoxia) may lead to osteonecrosis. Patients at increased risk for osteonecrosis should be monitored closely. Unfortunately, most cases are diagnosed in an advanced stage of disease, when minimally invasive surgical procedures are no longer helpful. Furthermore, patients in the advanced stage of the disease must undergo total hip replacement at a young age, which carries a poor long-term prognosis.

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Citations

Cites

Show all 15 references

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Cited by

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Metadata

Authors
Lavernia, C. J., Sierra, R. J., & Grieco, F. R.
Venue
Journal of the American Academy of Orthopaedic Surgeons
Published
1999-07
Volume
7
Issue
4
Pages
250-261
ISSN
1067-151X (ISSN-L)
OpenAlex
W1963317358
Cited by
395
References
15
FWCI
6.29
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Osteonecrosis of the Femoral Head. https://app.cochat.ai/papers/10.5435/00124635-199907000-00005
The paper
Lavernia, C. J., Sierra, R. J., & Grieco, F. R. (1999). Osteonecrosis of the Femoral Head. Journal of the American Academy of Orthopaedic Surgeons. https://doi.org/10.5435/00124635-199907000-00005

Data sources

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.