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Effects of Vitamin D on Skeletal Muscle and Athletic Performance
Abstract
Vitamin D is known to be important for calcium homeostasis and bone metabolism. It also has important direct effects on skeletal muscle. Unlike authentic vitamins, which cannot be synthesized in the body, vitamin D is produced in the skin using sunlight. Through its nuclear receptor (ie, vitamin D receptor) located throughout the body, including skeletal muscle, vitamin D initiates genomic and nongenomic pathways regulating multiple actions, including myocyte proliferation and growth. In some studies, vitamin D supplementation has been shown to increase muscle strength, particularly in people who are vitamin D deficient. Higher serum levels of vitamin D are associated with reduced injury rates and improved sports performance. In a subset of the population, vitamin D appears to play a role in muscle strength, injury prevention, and sports performance.
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“Vitamin D is an essential secosteroid hormone that plays a pivotal role in maintaining overall health, particularly regarding bone health, immune function, and muscle performance (Abrams et al. 2018; Harju et al. 2022).”
From Vitamin D status and its determinants in German elite athletes (2025) · cites this paper as Abrams et al. 2018
In the citing paper
“The identification of vitamin D receptors in skeletal muscle tissue (Bischoff et al. 2001; Bischoff-Ferrari et al. 2004) has led to growing evidence suggesting that vitamin D plays a role in muscle function, potentially impacting athletic performance (Abrams et al. 2018; de la Puente Yagüe et al. 2020).”
From Vitamin D status and its determinants in German elite athletes (2025) · cites this paper as Abrams et al. 2018
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“It has been reported that adequate vitamin D status maybe play a vital role in muscle remodeling [4,5].”
From The Associations of Vitamin D Status with Athletic Performance and Blood-borne Markers in Adolescent Athletes: A Cross-Sectional Study (2019) · cites this paper as [4]
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The roles of vitamin D in skeletal muscle: form, function, and metabolism
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Wentz, L. M., Liu, P.-Y., Ilich, J. Z., & Haymes, E. M. (2016) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2014-0177 · Cited by 21
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Cited by
Seo, M.-W., Song, J. K., Jung, H. C., Kim, S.-W., Kim, J.-H., & Lee, J.-M. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16183422 · Cited by 34
Vitamin D status and its determinants in German elite athletes
Hacker, S., Lenz, C., Reichert, L., Ringseis, R., Zentgraf, K., & Krüger, K. (2025) · European Journal of Applied Physiology · doi:10.1007/s00421-024-05699-6 · Cited by 9
Metadata
- Authors
- Abrams, G. D., Feldman, D., & Safran, M. R.
- Venue
- Journal of the American Academy of Orthopaedic Surgeons
- Published
- 2018-04-15
- Volume
- 26
- Issue
- 8
- Pages
- 278-285
- ISSN
- 1067-151X
- 1940-5480
- Cited by
- 58
- References
- 6
- Language
- en
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