A survey of cannabis (marijuana) use and self-reported benefit in men with chronic prostatitis/chronic pelvic pain syndrome
Open accessAbstract
Introduction: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a chronic pelvic pain condition largely refractory to treatment. Cannabis (marijuana) use has been reported for a wide variety of chronic pain conditions, but no study has examined prevalence of cannabis use, symptom benefit or side effects, or frequency in CP/CPPS.Methods: Participants were recruited from an outpatient CP/CPPS urology clinic (n = 98) and online through the Prostatitis Foundation website (n = 244). Participants completed questionnaires (demographics, CP/CPPS, depression, cannabis).Results: The clinic sample included Canadian patients and the online sample included primarily American patients. Due to differences, groups were examined separately. Almost 50% of respondents reported using cannabis (clinic n = 49; online n = 89). Of the cannabis users, 36.8% of clinic and 75% of online respondents reported that it improved their symptoms. Most of the respondents (from the clinic and online groups) reported that cannabis improved their mood, pain, muscle spasms, and sleep. However, they did not note any improvements for weakness, fatigue, numbness, ambulation, and urination. Overall, the effectiveness of cannabis for CP/CPPS was “somewhat/very effective” (57% clinic; 63% online). There were no differences between side effects or choice of consumptionand most reported using cannabis rarely.Conclusions: These are the first estimates in men suffering from CP/CPPS and suggest that while cannabis use is prevalent, its medical use and benefit are unknown. This is an understudied area and the benefit or hazard for cannabis use awaits further study.
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In the five studies on nausea in chronic pain, each involved whole plant cannabis in inhaled or oral formats, and patients reported moderate relief.
“Each study involved whole plant cannabis in inhaled or oral formats, with patients reporting moderate relief.”
From Clinical Practice Guidelines for Cannabis and Cannabinoid-Based Medicines in the Management of Chronic Pain and Co-Occurring Conditions (2024) · cites this paper as [85]
The Results report that some men with chronic prostatitis/chronic pelvic pain syndrome said cannabis made nausea 'slightly/much better'; Table 3 gives 41.7% in the clinic group and 52.6% in the online group. The Results and Table 4 show that herbal cannabis was commonly used and smoking was a leading preferred method, but they do not establish that patients used only inhaled or oral formats, or that their nausea relief was specifically moderate. (LLM, conf=0.86)
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Cites
Tabachnick, B. G., & Fidell, L. S. (1983) · Cited by 79,888 · see citing works
(2007) · Cited by 10,092 · see citing works
Spitzer, R. L. (1999) · JAMA · doi:10.1001/jama.282.18.1737 · Cited by 9,802 · see citing works
NIH Consensus Definition and Classification of Prostatitis
Krieger, J. N., Leroy Nyberg, Jr., & Nickel, J. C. (1999) · JAMA · doi:10.1001/jama.282.3.236 · Cited by 1,464 · see citing works
Self-citationLitwin, M. S., McNaughton‐Collins, M., Fowler, F. J., Nickel, J. C., Calhoun, E. A., Pontari, M. A., Alexander, R. B., Farrar, J. T., & O’Leary, M. P. (1999) · The Journal of Urology · doi:10.1016/s0022-5347(05)68562-x · Cited by 943 · see citing works
Self-citationNickel, J. C., Downey, J., Hunter, D., & Clark, J. (2001) · The Journal of Urology · doi:10.1016/s0022-5347(05)66541-x · Cited by 457 · see citing works
Self-citationCannabinoid–Opioid Interaction in Chronic Pain
Abrams, D. I., Couey, P., Shade, S. B., Kelly, M. E., & Benowitz, N. L. (2011) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.2011.188 · Cited by 319 · see citing works
Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
Xiong, W., Cui, T., Cheng, K., Yang, F., Chen, S.-R., Willenbring, D., Guan, Y., Pan, H., Ren, K., Xu, Y., et al. (2012) · The Journal of Experimental Medicine · doi:10.1084/jem.20120242 · Cited by 290 · see citing works
Management of Chronic Prostatitis/ Chronic Pelvic Pain Syndrome
Anothaisintawee, T. (2011) · JAMA · doi:10.1001/jama.2010.1913 · Cited by 277 · see citing works
Hazekamp, A., Ware, M. A., Müller‐Vahl, K., Abrams, D. I., & Grotenhermen, F. (2013) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2013.805976 · Cited by 242 · see citing works
Self-citationChronic Prostatitis and the Chronic Pelvic Pain Syndrome
Schaeffer, A. J. (2006) · New England Journal of Medicine · doi:10.1056/nejmcp060423 · Cited by 222 · see citing works
Chronic pelvic pains represent the most prominent urogenital symptoms of “chronic prostatitis”
Krieger, J. N., Egan, K. J., Ross, S. O., Jacobs, R., & Berger, R. E. (1996) · Urology · doi:10.1016/s0090-4295(96)00421-9 · Cited by 220 · see citing works
Therapeutic potential of monoacylglycerol lipase inhibitors
Mulvihill, M. M., & Nomura, D. K. (2012) · Life Sciences · doi:10.1016/j.lfs.2012.10.025 · Cited by 199 · see citing works
Cannabis use for chronic non-cancer pain: results of a prospective survey
Ware, M. A., Doyle, C. R., Woods, R., Lynch, M. E., & Clark, A. J. (2003) · Pain · doi:10.1016/s0304-3959(02)00400-1 · Cited by 185 · see citing works
Self-citationMundal, I. P., Gråwe, R. W., Bjørngaard, J. H., Linaker, O. M., & Fors, E. A. (2014) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-15-213 · Cited by 136 · see citing works
Cannabis as an Adjunct to or Substitute for Opiates in the Treatment of Chronic Pain
Lucas, P. (2012) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2012.684624 · Cited by 131 · see citing works
Hu, J. C., Link, C. L., McNaughton-Collins, M., Barry, M. J., & McKinlay, J. B. (2007) · Journal of General Internal Medicine · doi:10.1007/s11606-007-0341-y · Cited by 75 · see citing works
Nickel, J. C., Shoskes, D. A., & Wagenlehner, F. R. A. (2013) · World Journal of Urology · doi:10.1007/s00345-013-1062-y · Cited by 74 · see citing works
Self-citationAggarwal, S. K. (2013) · The Clinical Journal of Pain · doi:10.1097/ajp.0b013e31824c5e4c · Cited by 62 · see citing works
Tripp, D. A., Nickel, J. C., Shoskes, D. A., & Koljuskov, A. (2013) · World Journal of Urology · doi:10.1007/s00345-013-1067-6 · Cited by 58 · see citing works
Self-citationTripp, D. A., Nickel, J. C., Ross, S., et al. (2009) · British Journal of Urology · doi:10.1111/j.1464-410x.2008.08157.x · Cited by 42 · see citing works
Self-citationProstatitis‐like symptoms: one year later
Nickel, J. C., Downey, J., Nickel, K., & Clark, J. (2002) · British Journal of Urology · doi:10.1046/j.1464-410x.2002.03007.x · Cited by 38 · see citing works
Self-citationNickel, J. C. (2006) · Urology · doi:10.1016/j.urology.2006.04.013 · Cited by 35 · see citing works
Self-citationChronic Pain and Marijuana Use among a Nationally Representative Sample of Adults
Zvolensky, M. J., Cougle, J. R., Bonn‐Miller, M. O., Norberg, M. M., Johnson, K., Kosiba, J. D., & Asmundson, G. J. G. (2011) · American Journal on Addictions · doi:10.1111/j.1521-0391.2011.00176.x · Cited by 31 · see citing works
Chronic prostatitis-like symptoms in African males aged 16-19 years.
Tripp, D. A., Nickel, J. C., Pikard, J. L., et al. (2012) · PubMed · Cited by 11 · see citing works
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Bell, A. D., MacCallum, C., Margolese, S., Walsh, Z., Wright, P., Daeninck, P. J., Mandarino, E., Lacasse, G., Kaur Deol, J., de Freitas, L., et al. (2024) · Cannabis & Cannabinoid Research · doi:10.1089/can.2021.0156 · Cited by 78 · see citing works
- Authors
- Tripp, D. A., Nickel, J. C., Katz, L., Krsmanovic, A., Ware, M. A., & Santor, D.
- Affiliations
- Queen's University (CA)
- McGill University Health Centre (CA)
- University of Ottawa (CA)
- Venue
- Canadian Urological Association Journal
- Published
- 2014-12-15
- Volume
- 8
- Issue
- 11-12
- Pages
- 901
- ISSN
- 1911-6470 (ISSN-L)
- 1920-1214
- PMC
- PMC4277530
- OpenAlex
- W2076717220
- Cited by
- 22
- References
- 25
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 3 · 2021: 2 · 2020: 6 · 2019: 2 · 2018: 1 · 2017: 5 · 2016: 1
- FWCI
- 1.46
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Canadian Urological Association Journal (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Cannabis and Cannabinoid Research
- Health Sciences › Medicine › Urology › Urinary Bladder and Prostate Research
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Keywords
- cannabis use, cannabis, chronic prostatitis, cannabis side effects, prevalence, men, pain management, mood, sleep, muscle spasm
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