Cited by 33Burn Injury Management and OutcomesHemodynamic Monitoring and TherapySepsis Diagnosis and Treatment

An overview on fluid resuscitation and resuscitation endpoints in burns: Past, present and future. Part 1 — historical background, resuscitation fluid and adjunctive treatment

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Peeters, Yannick, Vandervelden, Stefanie, Wise, Robert, Malbrain, Manu L.N.G.·2015·Anestezjologia Intensywna Terapia

Abstract

An improved understanding of burn shock pathophysiology and subsequent development of fluid resuscitation strategies has led to dramatic outcome improvements in burn care during the 20th century. While organ hypoperfusion caused by inadequate resuscitation has become rare in clinical practice, there is growing concern that increased morbidity and mortality related to over-resuscitation is occurring more frequently in burn care. In order to reduce complications related to this concept of "fluid creep", such as respiratory failure and compartment syndromes, efforts should be made to resuscitate with the least amount of fluid in order to provide adequate organ perfusion. In this first part of a concise review, historic and current evidence regarding the available fluids is discussed, as well as some adjunctive treatments modulating the inflammatory response. In the second part, special reference will be made to the role of abdominal hypertension in burn care and the endpoints used to guide fluid resuscitation will be discussed. Finally, as urine output has been recognized as a poor resuscitation target, a resuscitation protocol is suggested in part two which includes new targets and endpoints that can be obtained with modern, less invasive hemodynamic monitoring devices.

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Registry

Crossref · 10.5603/ait.a2015.0063

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  • Other studies found that the use of high-dose vitamin C in patients with severe burns resulted in less positive fluid balance and less secondary abdominal hypertension.

    “Other studies found that the use of high-dose vitamin C in patients with severe burns resulted in less positive fluid balance and less secondary abdominal hypertension [84].”

    From Nutrition in Sepsis: A Bench-to-Bedside Review. (2020) · cites this paper as [84]

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Authors
Peeters, Y., Vandervelden, S., Wise, R., & Malbrain, M. L. N. G.
Affiliations
Ziekenhuisnetwerk Antwerpen Stuivenberg (BE)
Venue
Anestezjologia Intensywna Terapia
Published
2015-12-29
Volume
47
Issue
J
Pages
6-14
ISSN
  • 1642-5758 (ISSN-L)
  • 1731-2531
OpenAlex
W2161670539
Cited by
33
References
79
Citations by year
2026: 2 · 2025: 1 · 2024: 2 · 2023: 8 · 2022: 2 · 2021: 2 · 2020: 5 · 2019: 1 · 2018: 3 · 2017: 3 · 2016: 4
FWCI
2.62
Type
journal article
Language
en
Open access
Licence
cc-by-nc-sa
Locations
  • Anaesthesiology Intensive Therapy (publishedVersion, cc-by-nc-sa)
  • PubMed (publishedVersion)
  • Via Medica Journals (submittedVersion)
  • VUBIR (Vrije Universiteit Brussel) (submittedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Burn Injury Management and Outcomes
  • Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
  • Health Sciences › Medicine › Epidemiology › Sepsis Diagnosis and Treatment
Keywords
burn shock, fluid resuscitation, burn resuscitation, fluid creep, over-resuscitation, resuscitation endpoints, organ hypoperfusion, abdominal hypertension, urine output, hemodynamic monitoring, adjunctive therapy, inflammation modulation, compartment syndrome, respiratory failure
MeSH terms
Crystalloid Solutions, Albumins, Ascorbic Acid, Burns, Colloids, Fluid Therapy, Humans, Isotonic Solutions, Plasmapheresis, Resuscitation, Endpoint Determination

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