The DOI matches its Crossref record; 33 of the 34 references it cites were found in a registry or an index.
Effects of Nocturnal Continuous Positive Airway Pressure Therapy in Patients with Resistant Hypertension and Obstructive Sleep Apnea
Open accessAbstract
Study objective To examine the long-term effects of continuous positive airway pressure (CPAP) therapy on blood pressure (BP) in patients with obstructive sleep apnea and resistant hypertension.Methods Study subjects were 98 patients with obstructive sleep apnea syndrome and hypertension who had 3 or more documented daytime BP measurements taken within 3 months of enrollment and every 3 months after CPAP initiation for 1 year. Resistant hypertension was defined as daytime BP of at least 140 mm Hg systolic or 90 mm Hg diastolic, despite the use of 3 or more antihypertensive medications. Patients in the resistant hypertension group (n = 42) were compared with subjects with controlled hypertension (n = 56).Results Mean difference in mean arterial pressure was -5.6 (95% confidence interval [CI] -2.0 to -8.7 mm Hg; p = 0.03) in the resistant group and -0.8 mm Hg (95% CI -2.9 to 3.3 mm Hg; p = 0.53) in patients with controlled BP at the end of follow up period. CPAP permitted de-escalation of antihypertensive treatment in 71% of subjects with resistant hypertension but did not significantly alter the antihypertensive regimen in the controlled group. Multivariate regression analysis showed that baseline BP (odds ratio 5.4, 95% CI 2.3 to 8.9; p = 0.01) and diuretic therapy (odds ratio = 3.2, 95% CI 1.8 to 6.1; p = 0.02), but not apnea-hypopnea index or hours of CPAP use, were independently associated with a decrease in mean arterial pressure after 12 months of CPAP therapy.Conclusion In this observational study, CPAP was associated with different effects on blood pressure control in hypertensive patients with sleep apnea. A beneficial response to CPAP therapy was found mainly in subjects with the most severe hypertensive disease.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Poor BP control is strongly associated with OSA, especially in those patients with an apnea/hypopnea index of at least 30 events per hour.261”
From Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association (2018) · cites this paper as [261]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Prospective Study of the Association between Sleep-Disordered Breathing and Hypertension
Peppard, P. E., Young, T., Palta, M., & Skatrud, J. (2000) · New England Journal of Medicine · doi:10.1056/nejm200005113421901 · Cited by 4,973
Nieto, F. J. (2000) · JAMA · doi:10.1001/jama.283.14.1829 · Cited by 3,369
The Triad of Sleep Apnea, Hypertension, and Chronic Kidney Disease: A Spectrum of Common Pathology
Aziz, F., & Chaudhary, K. R. (2016) · Cardiorenal Medicine · doi:10.1159/000450796 · Cited by 3,285
Law, M. R., Wald, N. J., Morris, J. K., & Jordan, R. E. (2003) · BMJ · doi:10.1136/bmj.326.7404.1427 · Cited by 1,232
Pepperell, J., Ramdassingh-Dow, S., Crosthwaite, N., Mullins, R., Jenkinson, C., Stradling, J. R., & Davies, R. J. O. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07445-7 · Cited by 1,055
Population-Based Study of Sleep-Disordered Breathing as a Risk Factor for Hypertension
Young, T. B. (1997) · Archives of Internal Medicine · doi:10.1001/archinte.1997.00440360178019 · Cited by 967
Becker, H. F., Jerrentrup, A., Ploch, T., Grote, L., Penzel, T., Sullivan, C. E., & Peter, J. H. (2003) · Circulation · doi:10.1161/01.cir.0000042706.47107.7a · Cited by 931
Psaty, B. M. (1997) · JAMA · doi:10.1001/jama.1997.03540330061036 · Cited by 928
Effect of Intrathoracic Pressure on Left Ventricular Performance
Buda, A. J., Pinsky, M. R., Ingels, N. B., Daughters, G. T., Stinson, E. B., & Alderman, E. L. (1979) · New England Journal of Medicine · doi:10.1056/nejm197908303010901 · Cited by 813
Flagged first, then by citations
1 of the 34 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- Rechtschaffen A, Kales A. A Manual of Standardized Terminology, Techniques, and Scoring System for Sleep Stages of Human Subjects. US Department of Health, Education, and Welfare Public Health Service - NIH/NIND. 1968.
- Somers VK. Management of sleep apnea. In: Izzo JL Jr, Black HR, eds. Hypertension Primer: the Essentials of High Blood Pressure: Basic Science, Population Science, and Clinical Management. Philadelphia, PA: Lippincott Williams & Wilkins; 2003:512–6.
Cited by
Sorted by citations
Items 101–102 of 102
Calhoun, D. A. (2013) · Hypertension · doi:10.2217/ebo.12.349
Liu, J., Cui, Y., Liu, Y., Sima, M., Han, M., Ma, K., Yu, Z., Yue, D., & Bi, Y. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1785996
Metadata
- Authors
- Dernaika, T. A., Kinasewitz, G. T., & Tawk, M. M.
- Affiliations
- University of Oklahoma Medical Center (US)
- University of Oklahoma Health Sciences Center (US)
- Corresponding author
- Dernaika, Tarek A.
- Venue
- Journal of Clinical Sleep Medicine
- Published
- 2009-04-15
- Volume
- 5
- Issue
- 2
- Pages
- 103-107
- ISSN
- 1550-9389 (ISSN-L)
- 1550-9397
- PMC
- PMC2670326
- OpenAlex
- W219218098
- Cited by
- 102
- References
- 34
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 2 · 2022: 1 · 2020: 5 · 2019: 2 · 2018: 3 · 2017: 5 · 2016: 3 · 2015: 12 · 2014: 17 · 2013: 11 · 2012: 16
- FWCI
- 8.61
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Clinical Sleep Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Keywords
- continuous positive airway pressure, obstructive sleep apnea, resistant hypertension, blood pressure control, diuretic therapy, mean arterial pressure, apnea-hypopnea index
- MeSH terms
- Antihypertensive Agents, Drug Resistance, Female, Humans, Hypertension, Male, Middle Aged, Retrospective Studies, Comorbidity, Multivariate Analysis, Logistic Models, Sleep Apnea, Obstructive, Continuous Positive Airway Pressure
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
